Zobrazeno 1 - 10
of 73
pro vyhledávání: '"D K Blanchard"'
Publikováno v:
International Journal of Gynecological Cancer. 6:27-37
We report in this study that human peritoneal mesothelial cells can lyse human malignant ovarian cells. Recombinant human interferon (IFN)-γ and rhTNF-α significantly activated cytotoxicity of mesothelial cells against the tumor necrosis factor (TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::418f32920ec74eb27950bc0f7339e54f
https://doi.org/10.1046/j.1525-1438.1996.06010027.x
https://doi.org/10.1046/j.1525-1438.1996.06010027.x
Autor:
D.P.J. Barton, D K Blanchard, Steven L. DeCesare, Chunni Duan, Julie Y. Djeu, Denis Cavanagh, William S. Roberts
Publikováno v:
Journal of the Society for Gynecologic Investigation. 2:762-771
The ascites-associated lymphocytes in ovarian cancer have altered immunologic function, and cell-free ascitic fluid has immunomodulating properties. We determined (1) whether interleukin (IL)-2 could induce lymphokine-activated killer (LAK) activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123fea5273c821b7ab5f6297a9b86c20
https://doi.org/10.1016/1071-5576(95)94692-n
https://doi.org/10.1016/1071-5576(95)94692-n
Publikováno v:
Blood. 85:3173-3182
The lysis of antigen presenting cells (APCs) by cytotoxic T lymphocytes (CTLs) may be one mechanism whereby an immune response is downregulated by Staphylococcus superantigens. Disappearance of monocytes/macrophages from staphylococcal enterotoxin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c29f76cbe47d4c2e78cb53792fa97c4
https://doi.org/10.1182/blood.v85.11.3173.bloodjournal85113173
https://doi.org/10.1182/blood.v85.11.3173.bloodjournal85113173
Publikováno v:
Journal of Cellular Biochemistry. 57:452-464
Lysis of human culture-derived macrophages by extracellular ATP has recently been described, and treatment of macrophages with interferon-gamma rendered those cells significantly more sensitive to lysis. In addition, cell death occurred more rapidly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d33754e3e6317b7bdec6d0f5aa85e3
https://doi.org/10.1002/jcb.240570311
https://doi.org/10.1002/jcb.240570311
Publikováno v:
Cellular Immunology. 156:24-35
NK cells can recognize and lyse target cells without restriction by the MHC. The molecular interaction responsible for NK cell recognition is poorly understood. It has been frequently suggested that the loss of beta 2 integrin in immune competent cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3351792f515161412ceec0a833ec2cd
https://doi.org/10.1006/cimm.1994.1150
https://doi.org/10.1006/cimm.1994.1150
Publikováno v:
The Journal of Immunology. 152:3630-3636
Induction of IL-8 gene expression was investigated in IL-2-stimulated circulating peripheral blood polymorphonuclear neutrophils (PMN). Brief exposure of normal PMN to human rIL-2 enhanced both transcriptional and translational expression of IL-8. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2715f68101b98255bef6e7952a6aff20
https://doi.org/10.4049/jimmunol.152.7.3630
https://doi.org/10.4049/jimmunol.152.7.3630
Autor:
J. V. Fiorica, B. Michelini-Norris, W. S. Roberts, S. V. Nicosia, D. P. J. Barton, D. Cavanagh, J. Y. Djeu, D. K. Blanchard, M. S. Hoffman
Publikováno v:
American Journal of Reproductive Immunology. 30:202-206
PROBLEM: To determine the early effect of abdominal cytoreductive surgery on serum soluble interleukin-2 receptor alpha (sIL-2R alpha) levels in patients with ovarian and cervical cancer, and to determine if the extent of cytoreduction correlated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0a37a88f885841bab96d007d5f00dd
https://doi.org/10.1111/j.1600-0897.1993.tb00621.x
https://doi.org/10.1111/j.1600-0897.1993.tb00621.x
Publikováno v:
Blood. 82:1578-1585
The present study shows that extracellular adenosine triphosphate (ATP) has the capacity to mediate dose-dependent lysis of the monocytic leukemia cell line THP-1. The lysis, assessed by 51Cr release, was found to be selective for ATP, because adenos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e943ac3a32a409fdace86ba5b304abe3
https://doi.org/10.1182/blood.v82.5.1578.1578
https://doi.org/10.1182/blood.v82.5.1578.1578
Publikováno v:
The Journal of Immunology. 150:1979-1987
In addition to T cells, NK cells, B cells, and monocytes, we provide new evidence that human polymorphonuclear neutrophils (PMN) can be functionally activated by IL-2 via binding to IL-2R beta expressed on the cell surface. Brief exposure of normal P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456eb21658cea7f0a66cc990018683dc
https://doi.org/10.4049/jimmunol.150.5.1979
https://doi.org/10.4049/jimmunol.150.5.1979
Publikováno v:
The Journal of Immunology. 150:960-970
Polymorphonuclear neutrophils (PMN) are essential components of the host defense system against a wide variety of pathogens. We report here the novel finding that freshly isolated human PMN constitutively express detectable surface levels of IL-2R be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa46181470163052f1e2275b321d2bac
https://doi.org/10.4049/jimmunol.150.3.960
https://doi.org/10.4049/jimmunol.150.3.960