Výsledky vyhledávání - "D J Squirrell"

Immunoassays in a porous silicon interferometric biosensor combined with sensitive signal processing

Autor: M. H. Anderson, E. A. Perkins, S. Hayward, S. Nicklin, R. G. Smith, A.-S. Wilkinson, A. Green, D. J. Squirrell, Timothy I. Cox, L. Koker, A. Tinsley-Bown, A. J. Simons, A. Hutchinson, R. Torrens

Publikováno v: physica status solidi (a). 202:1347-1356

Orthogonal subspace signal processing algorithms (OSPA) have been developed to extract the optical thickness of a porous silicon layer to within one part in 10 5 from its reflectivity spectrum. This is equivalent to a limit of detection (LOD) of -40

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::506fd1e3008aad052ba5448299fd8509
https://doi.org/10.1002/pssa.200461101

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Sensitivity of the optical properties of porous silicon layers to the refractive index of liquid in the pores

Autor: R. G. Smith, Philip Allcock, D. J. Squirrell, M. Hollings, S. Nicklin, C. Reeves, Timothy I. Cox, P. A. Snow, A. Tinsley-Bown, M. A. Anderson, E. A. Perkins

Publikováno v: physica status solidi (a). 197:528-533

The sensitivity of the optical reflectivity of porous silicon structures to the refractive index of liquid within the pores is studied for a single layer, a Bragg mirror and a microcavity. Sucrose solutions of concentration in the range 0.05 to 1.0%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e814e1bd8b0b26215bc5d6faace8643
https://doi.org/10.1002/pssa.200306558

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Development of a thermostable firefly luciferase

Autor: Christopher R. Lowe, M.J Murphy, James A. H. Murray, Peter John White, L. C. Tisi, D. J. Squirrell

Publikováno v: Analytica Chimica Acta. 457:115-123

Firefly luciferase forms the basis of a wide range of analytical techniques. However, the enzyme is unstable and rapidly loses activity even at room temperature. This leads to losses in sensitivity and precision in analytical applications and also se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1ef070f5e3adc8d527c18a83650350e
https://doi.org/10.1016/s0003-2670(01)01496-9

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Tuning the Pore Size and Surface Chemistry of Porous Silicon for Immunoassays

Autor: S. Nicklin, D. J. Squirrell, E. A. Perkins, M. Hollings, Timothy I. Cox, M.H. Anderson, Michael J. Sailor, Leigh T. Canham, A. Tinsley-Bown, A. Wun, C. L. Reeves, A. Hutchinson

Publikováno v: physica status solidi (a). 182:547-553

To use porous silicon as an optical interferometric biosensor, the pores must be sufficiently large to allow easy ingress of reagents and the layer must also display Fabry-Perot optical cavity modes. Here the detection antibody is rabbit IgG and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8963c1520187607ca3d6a283519e49be
https://doi.org/10.1002/1521-396x(200011)182:1<547::aid-pssa547>3.0.co

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