Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D J Shealy"'
Autor:
W C Bogard, S A Siegel, A O Leone, E Damiano, D J Shealy, T M Ely, B Frederick, M A Mascelli, R C Siegel, B Machielse
Publikováno v:
The Journal of Immunology. 150:4438-4449
HA-1A, a human IgM mAb, has been shown to significantly reduce mortality in septic patients with Gram-negative bacteremia, especially those with septic shock, in a controlled clinical trial. To confirm the reported specificity of this antibody for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bcfb53c69b530ff3a93d567ab9d76d1
https://doi.org/10.4049/jimmunol.150.10.4438
https://doi.org/10.4049/jimmunol.150.10.4438
Autor:
S. Visvanathan, D. J. Shealy
Publikováno v:
Therapeutic Antibodies ISBN: 9783540732587
Tumor necrosis factor alpha (TNF) is an important cell-signaling component of the immune system. Since its discovery over 20 years ago, much has been learned about its functions under normal and disease conditions. Nonclinical studies suggested a rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b656254f9ef4e1c59303f40bf00459e9
https://doi.org/10.1007/978-3-540-73259-4_5
https://doi.org/10.1007/978-3-540-73259-4_5
Autor:
D J, Shealy, S, Visvanathan
Publikováno v:
Handbook of experimental pharmacology. (181)
Tumor necrosis factor alpha (TNF) is an important cell-signaling component of the immune system. Since its discovery over 20 years ago, much has been learned about its functions under normal and disease conditions. Nonclinical studies suggested a rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::add7ef96cc471881a64beff64a05131b
https://pubmed.ncbi.nlm.nih.gov/18071943
https://pubmed.ncbi.nlm.nih.gov/18071943
Autor:
W C, Bogard, S A, Siegel, A O, Leone, E, Damiano, D J, Shealy, T M, Ely, B, Frederick, M A, Mascelli, R C, Siegel, B, Machielse
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 150(10)
HA-1A, a human IgM mAb, has been shown to significantly reduce mortality in septic patients with Gram-negative bacteremia, especially those with septic shock, in a controlled clinical trial. To confirm the reported specificity of this antibody for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfdc561d3524004c9a18d38b977966fd
https://pubmed.ncbi.nlm.nih.gov/7683319
https://pubmed.ncbi.nlm.nih.gov/7683319
Autor:
B. Frederick, D. J. Shealy, Koon Yan Pak, Mary Ann Mascelli, D. S. Neblock, Peter Daddona, T M Ely
Publikováno v:
Infection and immunity. 61(5)
Clinical data suggest that the human immunoglobulin M antiendotoxin antibody HA-1A reduced mortality in patients diagnosed with gram-negative bacteremia and bacteremia with shock. Previous studies have demonstrated that HA-1A binds to the lipid A dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47037dd43a26d38fbdd52997ba6ccedc
https://pubmed.ncbi.nlm.nih.gov/8478065
https://pubmed.ncbi.nlm.nih.gov/8478065
Autor:
M A, Nedelman, D J, Shealy, R, Boulin, E, Brunt, J I, Seasholtz, I E, Allen, J E, McCartney, F D, Warren, H, Oppermann, R H, Pang
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 34(2)
Studies of monoclonal antibody-based imaging agents show that blood clearance is inversely proportional to molecular size, i.e., Fab or Fab'F(ab')2IgG. Indium-111-antimyosin Fab-DTPA is a highly specific and sensitive marker for myocardial necrosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27f0f4d8f7e6426b5241f3ff73148d7d
https://pubmed.ncbi.nlm.nih.gov/8429342
https://pubmed.ncbi.nlm.nih.gov/8429342
Publikováno v:
Journal of Biological Chemistry. 256:11381-11384
Treatment of A-431 human epidermoid carcinoma cells with epidermal growth factor (EGF) was shown to enhance the phosphorylation of a Mr = 34,000 protein. Because the phosphorylation of an analogous protein is enhanced in various cell lines transforme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d00d5790650fbe8b43d9c319735be0
https://doi.org/10.1016/s0021-9258(19)68405-x
https://doi.org/10.1016/s0021-9258(19)68405-x
Autor:
D J Shealy, R R Rueckert
Publikováno v:
Journal of virology. 26(2)
Cells infected by Rous-associated virus 61 (RAV-61) contained a precursor-like protein, pr90, that was specifically precipitated by antiserum directed against envelope glycoproteins, gp85 and gp35. Tryptic peptide mapping showed that pr90 contained t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19734a798f4cd8021a74365fdfe7b1c5
https://pubmed.ncbi.nlm.nih.gov/77910
https://pubmed.ncbi.nlm.nih.gov/77910
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 29(4)
Monoclonal antibody 59D8 developed by Hui et al., binds to fibrin but not fibrinogen. An 111In-labeled Fab fragment of 59D8 was studied in vitro and in animal models to evaluate its potential for imaging thrombi and emboli in man. Rabbits and dogs we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddeaa6e1cfdd1d9f517f7e1e6eae4323
https://pubmed.ncbi.nlm.nih.gov/3351604
https://pubmed.ncbi.nlm.nih.gov/3351604
Publikováno v:
The Journal of biological chemistry. 256(22)
Treatment of A-431 human epidermoid carcinoma cells with epidermal growth factor (EGF) was shown to enhance the phosphorylation of a Mr = 34,000 protein. Because the phosphorylation of an analogous protein is enhanced in various cell lines transforme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b113186331b5cd697c663205ba5f1c61
https://pubmed.ncbi.nlm.nih.gov/6271744
https://pubmed.ncbi.nlm.nih.gov/6271744