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Autor:
T E Hamel, Stephanie L. Coffing, Robert L. Geahlen, D J Riese nd, Fanrong Mu, J Johnson, Mark Cushman, P Verdier-Pinard
Publikováno v:
Journal of Medicinal Chemistry. 44:441-452
A series of N-alkylamide analogues of the lavendustin A pharmacophore were synthesized and tested for inhibition of the epidermal growth factor receptor (EGFR) protein tyrosine kinase and the nonreceptor protein tyrosine kinase Syk. Although several