Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D J Kelvin"'
Publikováno v:
The Journal of Immunology. 150:3022-3029
The human macrophage inflammatory proteins-1 alpha and -beta (MIP-1 alpha and -beta), which are also known as LD78 and ACT2, respectively, are distinct but highly related members of the chemoattractant cytokine (chemokine) family. rMIP-1 alpha and -b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a9a1117edb91b5b42c88de941d83a8
https://doi.org/10.4049/jimmunol.150.7.3022
https://doi.org/10.4049/jimmunol.150.7.3022
Publikováno v:
The Journal of biological chemistry. 276(38)
The metabotropic glutamate receptors (mGluR), mGluR1a and mGluR5a, are G protein-coupled receptors that couple via G(q) to the hydrolysis of phosphoinositides, the release of Ca(2+) from intracellular stores, and the activation of protein kinase C (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9852f206720d0819a9cf0f3122364bef
https://pubmed.ncbi.nlm.nih.gov/11461909
https://pubmed.ncbi.nlm.nih.gov/11461909
Autor:
J, Barlic, J D, Andrews, A A, Kelvin, S E, Bosinger, M E, DeVries, L, Xu, T, Dobransky, R D, Feldman, S S, Ferguson, D J, Kelvin
Publikováno v:
Nature immunology. 1(3)
Chemoattractant-stimulated granule release from neutrophils, basophils and eosinophils is critical for the innate immune response against infectious bacteria. Interleukin 8 (IL-8) activation of the chemokine receptor CXCRI was found to stimulate rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18fdd165aabdd46a0cddd5a77174a0ef
https://pubmed.ncbi.nlm.nih.gov/10973280
https://pubmed.ncbi.nlm.nih.gov/10973280
Autor:
L, Xu, M H, Khandaker, J, Barlic, L, Ran, M L, Borja, J, Madrenas, R, Rahimpour, K, Chen, G, Mitchell, C M, Tan, M, DeVries, R D, Feldman, D J, Kelvin
Publikováno v:
European journal of immunology. 30(1)
In the present study, we explored the molecular mechanisms by which bacterial endotoxin (LPS) mediates the down-regulation of CCR2 receptors on human monocytes. We found that LPS induced a marked reduction in CCR2 cell surface protein levels which wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bffc486f91ee0d643e90b4ef54a35d9c
https://pubmed.ncbi.nlm.nih.gov/10602045
https://pubmed.ncbi.nlm.nih.gov/10602045
Autor:
G B, Mitchell, M H, Khandaker, R, Rahimpour, L, Xu, A I, Lazarovits, J G, Pickering, H, Suria, J, Madrenas, D K, Pomerantz, R D, Feldman, D J, Kelvin
Publikováno v:
European journal of immunology. 29(5)
All leukocytes express the cell surface glycoprotein CD45, which has intrinsic intracellular protein tyrosine phosphatase activity. CD45 is known to play a regulatory role in activation-induced signaling in lymphocytes; however, little is known of it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b5b5a236f9417eea704ee26bca8712d
https://pubmed.ncbi.nlm.nih.gov/10359100
https://pubmed.ncbi.nlm.nih.gov/10359100
Autor:
M H, Khandaker, G, Mitchell, L, Xu, J D, Andrews, R, Singh, H, Leung, J, Madrenas, S S, Ferguson, R D, Feldman, D J, Kelvin
Publikováno v:
Blood. 93(7)
The neutrophil-specific G-protein-coupled chemokine receptors, CXCR1 and CXCR2, bind with high affinity to the potent chemoattractant interleukin-8 (IL-8). The mechanisms of IL-8 receptor regulation are not well defined, although previous studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::714218ee18e8b21d4d540d6a9611cc38
https://pubmed.ncbi.nlm.nih.gov/10090924
https://pubmed.ncbi.nlm.nih.gov/10090924
Autor:
R, Rahimpour, G, Mitchell, M H, Khandaker, C, Kong, B, Singh, L, Xu, A, Ochi, R D, Feldman, J G, Pickering, B M, Gill, D J, Kelvin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(4)
Staphylococcal superantigens (SAgs) are very potent T cell mitogens, but they can also activate monocytes by binding directly to MHC class II molecules in a manner independent of TCR coengagement. Induction of proinflammatory cytokines and chemokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbe9105293aa9e9312b19d458d96da46
https://pubmed.ncbi.nlm.nih.gov/9973507
https://pubmed.ncbi.nlm.nih.gov/9973507
Autor:
M H, Khandaker, L, Xu, R, Rahimpour, G, Mitchell, M E, DeVries, J G, Pickering, S K, Singhal, R D, Feldman, D J, Kelvin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(4)
The expression of the seven-transmembrane domain chemokine receptors CXCR1 and CXCR2 modulates neutrophil responsiveness to the chemoattractant IL-8 and a number of closely related CXC chemokines. In the present study, we investigated the mechanism b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2edea152edbb32fe7500ae90c1e30297
https://pubmed.ncbi.nlm.nih.gov/9712063
https://pubmed.ncbi.nlm.nih.gov/9712063
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(3)
Chemokines are a family of structurally related, low m.w. proteins that regulate leukocyte migration both in vitro and in vivo. By virtue of their target cell specificity, chemokines have the potential to selectively recruit leukocyte subpopulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fecad775b315d95787b56a469d495de
https://pubmed.ncbi.nlm.nih.gov/8558019
https://pubmed.ncbi.nlm.nih.gov/8558019
Autor:
A, Ben-Baruch, K M, Bengali, A, Biragyn, J J, Johnston, J M, Wang, J, Kim, A, Chuntharapai, D F, Michiel, J J, Oppenheim, D J, Kelvin
Publikováno v:
The Journal of biological chemistry. 270(16)
Two interleukin-8 (IL-8) receptors, alpha and beta, have been identified and cloned. Both receptors are thought to transduce signals by coupling to GTP-binding proteins. The aim of this study is to determine whether the carboxyl terminus (C') of IL-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38d4a83513d2be446ada0ee24ff7e6a6
https://pubmed.ncbi.nlm.nih.gov/7721826
https://pubmed.ncbi.nlm.nih.gov/7721826