Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D J Gaertner"'
Publikováno v:
Virus Research
Rat coronaviruses (RCVs) infect laboratory rats and confound biomedical research results. In vitro systems developed so far have limited the growth in knowledge about RCVs by not permitting generation of plaque-cloned virus stocks, reliable isolation
Autor:
Frank X. Paturzo, Robert O. Jacoby, Abigail L. Smith, Elizabeth A. Johnson, D J Gaertner, Janet L. Brandsma
Publikováno v:
Virus Research. 28:1-18
In situ hybridization and virus titration were used to characterize early stages of rat virus (RV) infection of rat pups after oronasal inoculation. Results suggest that virus enters through the lung and that early viremia leads rapidly to pantropic
Publikováno v:
Archives of Virology
Summary Cell lines of rodent origin were tested for susceptibility to infection with rat coronavirus (RCV), including sialodacryoadenitis virus (SDAV) and Parker's rat coronavirus (PRCV). LBC rat mammary adenocarcinoma cells were susceptible only if
Autor:
D J, Gaertner
Publikováno v:
Contemporary topics in laboratory animal science. 40(5)
Autor:
D J, Gaertner
Publikováno v:
Contemporary topics in laboratory animal science. 39(6)
Publikováno v:
Virus research. 44(1)
Parvoviruses are prevalent and disruptive infectious agents of laboratory rats. Risks to rat-based research from infection are increased by the persistence of virus in immune rats and by prenatal transmission of infection. The mechanisms leading to v
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(8)
Inoculation of the UMass strain of rat virus (RV-UMass) into adult immunocompetent rats results in a prolonged subclinical infection that is resolved in 4 to 8 wk. Co-labeling studies, using in situ hybridization (ISH) and immunohistochemistry (IHC),
Publikováno v:
Laboratory animal science. 45(3)
In contrast to euthymic juvenile rats, which develop acute, self-limiting infection with rat virus (RV), RV infection of juvenile athymic rats was persistent for up to 12 weeks as demonstrated by recovery of infective virus, transmission to cagemates
Publikováno v:
Journal of Virological Methods
Enterotropic mouse hepatitis virus (MHV) strains have been difficult to grow in cell culture. In an attempt to develop an efficient in vitro cultivation system for enterotropic MHV strains (MHV-RI and MHV-Y), 8 murine cell lines were inoculated with
Publikováno v:
Laboratory animal science. 43(5)