Assessing the Course of Organ Dysfunction Using Joint Longitudinal and Time-to-Event Modeling in the Vasopressin and Septic Shock Trial

Autor: Michael O. Harhay, PhD, Alessandro Gasparini, PhD, Allan J. Walkey, MD, MS, Gary E. Weissman, MD, MSHP, Michael J. Crowther, PhD, Sarah J. Ratcliffe, PhD, James A. Russell, MD, on behalf of the Vasopressin and Septic Shock Trial (VASST) Investigators, J. A. Russell, K. R. Walley, C. L. Holmes Boulton, J. T. Granton, P. C. Hebert, D. J. Cooper, S. Mehta, J. Singer, A. C. Gordon, M. M. Storms, S. Jones, G. R. Bernard, A. S. Slutsky, G. A. Wells, A. Gasparini, B. Savage, D. Ayers, R. Woods, K. Wu, M. Maralit, L. Smith, K. Foley, A. Suri, M. Steinberg, B. Howe, P. Galt, A. Higgins, M. E. LeBlanc, A. M. Sutherland, A. Sham, A. McLeod, D. R. Dorscheid, M. Hameed, L. Lazosky, S. Helderweirt, C. Honeyman, T. Terins, D. Chittock, J. Ronco, S. Logie, G. Wood, F. Auld, V. Stedham, M. Mantle, L. Fox, G. D. McCauley, J. D. Rolf, C. Erbacher, G. Martinka, S. Goulding, S. Silverwood, L. Leung, S. Keenan, J. Murray, M. Van Osch, B. Light, M. Dominique, P. Gray, R. Stimpson, S. Rosser, D. Bell, W. Janz, T. McArdle, I. Watpool, A. Matte-Martyn, D. J Cook, E. McDonald, F. Clarke, A. Tkaczyk, N. Zytaruk, T. Stewart, C. Martinez-Motta, R. MacDonald, V. Sivanantham, R. Hodder, J. Foxall, M. Lewis, M. Ward, C. Dos Santos, J. Friedrich, D. Scales, O. Smith, I. DeCampos, A. Richards, H. Michalopoulos, U. Bakshi, W. Sibbald, T. Smith, K. Code, B. Bojilov, C. Dale, M. Keogh, M. Meade, L. Hand, C. Martin, J. Kehoe, V. Binns, M. McGuire, G. Poirier, L. Provost, J. Muscedere, C. Diemer, V. Pellegrino, A. Hilton, S. Morrison, C. Weatherburn, K. Moulden, C. Harry, J. J. Presneill, M. S Robertson, J. F. Cade, B. D. Howe, D. K. Barge, C. A. Boyce, F. Healy, C. Wright, D. Weyandt, J. Barrett, C. Walker, S. Burton, G. Dobb, S. Perryman, J. Chamberlain, L. Thomas, A. Bersten, L. Daly, T. Hunt, D. Wood, B. Patel, J. Larson, M. Rady, G. LeBrun, E. Boyd, R. Rush

Publikováno v: Critical Care Explorations, Vol 2, Iss 4, p e0104 (2020)

Objectives:. Non-mortality septic shock outcomes (e.g., Sequential Organ Failure Assessment score) are important clinical endpoints in pivotal sepsis trials. However, comparisons of observed longitudinal non-mortality outcomes between study groups ca

Externí odkaz: https://doaj.org/article/2056019742ec46f58eab1b0a39ae1800

Awake Prone Positioning in Acute Hypoxemic Respiratory Failure from COVID-19: A Randomized Clinical Trial

Autor: W Alhazzani, K K S Parhar, J Weatherald, Z Al Duhailib, M Alshahrani, A Al-Fares, S Buabbas, S V Cherian, L Munshi, E Fan, F Al-Hameed, J Chalabi, A A Rahmatullah, E Duan, J L Tsang, K Lewis, F Lauzier, J Centofanti, B Rochwerg, S Culgin, K Nelson, S A Abdukahil, K M Fiest, H T Stelfox, H Tlayjeh, M O Meade, D Perri, K Solverson, D J Niven, R Lim, M H Møller, E Belley-Cote, L Thabane, H Tamim, D J Cook, Y M Arabi

Publikováno v: 02.01 - Acute critical care.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f9d52225c99ca2f5f6d8a1228858343
https://doi.org/10.1183/13993003.congress-2022.3107

Additional file 1: of Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study

Autor: F. Lauzier, N. K. Adhikari, A. Seely, K. K. Y. Koo, E. P. Belley-CôTé, K. E. A. Burns, D. J. Cook, F. D’Aragon, B. Rochwerg, M. E. Kho, S. J. W. Oczkowksi, E. H. Duan, M. O. Meade, A. G. Day, F. Lamontagne

Adjudication of potential protocol deviations. (DOCX 18 kb)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b15c82f35462a62613c492baf372cfa

Metamorphism and deformation of mafic and felsic rocks in a magma transfer zone, Stewart Island, New Zealand

Autor: N. D. J. Cook, William J. Collins, Ron H. Vernon

Publikováno v: Journal of Metamorphic Geology. 30:473-488

In the mingled mafic/felsic Halfmoon Pluton at The Neck, Stewart Island (part of the Median Batholith of New Zealand) some hornblende gabbros and diorites retain magmatic structures, whereas others show evidence of major changes in grain and inclusio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1df7dce2fccf9e010135b68e1f65d440
https://doi.org/10.1111/j.1525-1314.2012.00977.x

Gastrointestinal transit in children with chronic idiopathic constipation

Autor: Sebastian K. King, Bridget R. Southwell, John M. Hutson, Jonathan Sutcliffe, D J Cook

Publikováno v: Pediatric Surgery International. 25:465-472

Chronic constipation in children is common and produces significant morbidity. Identification of the site of dysmotility in constipation may determine the cause and permit directed management. Scintigraphy differentiates constipated patients with ano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c99fd82cb54a0bbba839087451918fd
https://doi.org/10.1007/s00383-009-2374-2