Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine- trans -lactams

Autor: S J, Macdonald, M D, Dowle, L A, Harrison, J E, Spooner, P, Shah, M R, Johnson, G G, Inglis, G D, Clarke, D J, Belton, R A, Smith, C R, Molloy, M, Dixon, G, Murkitt, R E, Godward, T, Skarzynski, O M, Singh, K A, Kumar, S T, Hodgson, E, McDonald, G W, Hardy, H, Finch, D C, Humphreys, G, Fleetwood

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 11:243-246

Described are the acylation binding of trans-lactam 1 to porcine pancreatic elastase, the selection of the SO2Me activating group for the lactam N which also confers metabolic stability in hamster liver microsomes, the introduction of aqueous solubil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132a323ceabbf01bd4592fae3fbfa451
https://doi.org/10.1016/s0960-894x(00)00632-6

Infrared and liquid chromatographic characterization of epoxy cresol novolac-phenol formaldehyde novolac-tertiary amine resin systems

Autor: D. J. Belton, Eileen A. Sullivan

Publikováno v: Journal of Applied Polymer Science. 31:1309-1326

The subject of this paper is an infrared and liquid chromatographic characterization of epoxy molding compounds of importance in the microelectronic manufacturing industry. A complete infrared description of resin extracts from 4000 to 700 cm−1 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea050409d0370b154784b10d6202b71f
https://doi.org/10.1002/app.1986.070310516

Persistent lymphocytosis and virus-like particles in lymphocytes of sheep inoculated with cell-free extracts derived from ovine malignant lymphomas

Autor: D J Belton, AC Johnstone, R. D. Jolly, B. W. Manktelow

Publikováno v: The Journal of pathology. 128(4)

White cell counts of sheep inoculated in utero or at birth with cell-free extracts of ovine malignant lymphomas have been monitored for 5 yr. Of 28 inoculated sheep which have survived, 19 have shown persistent lymphocytosis. After 5 yr, no lymphomas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89198c7a29dc337ff739894094ba0ffe
https://pubmed.ncbi.nlm.nih.gov/521863

The Relationship Between Adhesion and Polyelectrolyte Solution Conformation as Studied by Fourier Transform IR Spectroscopy

Autor: D. J. Belton, S. I. Stupp

Publikováno v: Adhesion Aspects of Polymeric Coatings ISBN: 9781461336600

The adsorption behavior of polyelectrolyte macro-molecules at an ionic interface, in part, define the ability of that polymer to function as an adhesive. The effects of altering macromolecular solution conformation, via added electrolyte, upon the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3543ee2578a6d807cf6e7659f5915726
https://doi.org/10.1007/978-1-4613-3658-7_12

The Effect of γ-Aps Substrate Modification Upon the Chemical Adhesion of Poly(Amic Acid-Imide) Films

Autor: A. Joshi, D. J. Belton

Publikováno v: Molecular Characterization of Composite Interfaces ISBN: 9783662275979
Molecular Characterization of Composite Interfaces ISBN: 9781489922533

The chemical adhesion of poly(amic acid-imide), PAI, films upon silicon, silicon nitride, silicon dioxide and aluminum substrates was examined as a function of surface modification by γ-aminopropyltriethoxysilane, (γ-APS). In these systems it has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d4ff544c32521c98e938edf7c33b20
https://doi.org/10.1007/978-3-662-29084-2_12