Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D J, Woollard"'
Autor:
Jean-Pierre Y. Scheerlinck, Jan M. Tennent, Gerard Casey, Paul J. Chaplin, D. J. Woollard, Marshall W. Lightowlers, Peter McWaters, Julie Kelly
Publikováno v:
Vaccine. 19:4053-4060
A large-scale DNA vaccination trial was performed in sheep to investigate whether co-delivery of the cytokine genes IL-4, IL-5, IL-15, GM-CSF or IFN-γ could modulate the immune response generated to an antigen, in a DNA prime-recombinant protein boo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb217fd78574b23d498fed5844c2ec26
https://doi.org/10.1016/s0264-410x(01)00133-5
https://doi.org/10.1016/s0264-410x(01)00133-5
Publikováno v:
Parasitology. 121:145-153
Four synthetic peptides which comprise the immunodominant linear epitopes of the EG95 recombinant protein, were investigated for their ability to induce host-protective immunity against Echinococcus granulosus in sheep. Sheep were immunized with eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea5e679da2cc081d5b405e7165be95b
https://doi.org/10.1017/s0031182099006186
https://doi.org/10.1017/s0031182099006186
Autor:
Louise M Burrell, D. J. Woollard, John Risvanis, Colin I. Johnston, Nicole K. Farina, David Casely
Publikováno v:
Clinical Science. 93:43-50
1. Inhibition of neutral endopeptidase (NEP), the degradative enzyme for atrial natriuretic peptide, was studied in vitro and in vivo using a previously characterized NEP inhibitor radioligand, 125I-labelled RB104. 2. SCH 42354, the active di-acid of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae37d0e5f914ff089f57e832f06f3795
https://doi.org/10.1042/cs0930043
https://doi.org/10.1042/cs0930043
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 349:455-462
A range of agonists and antagonists were used to characterize the receptors through which 5-hydroxytryptamine (5-HT) contracts and relaxes the longitudinal muscle of segments of guinea-pig distal colon, in vitro. 5-HT contracted the longitudinal musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb3c94263421ba17a2f0c1880bad34c
https://doi.org/10.1007/bf00169133
https://doi.org/10.1007/bf00169133
Autor:
M D, Berzsenyi, S K, Roberts, S, Preiss, D J, Woollard, M R, Beard, N A, Skinner, D S, Bowden, K, Visvanathan
Publikováno v:
Journal of viral hepatitis. 18(12)
Signalling activated by Toll-like receptors (TLRs) can result in the production of tumour necrosis factor alpha (TNF-α) which is implicated in hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection. No study has examined or compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d310732c2b37b70b829b9a8692c7349
https://pubmed.ncbi.nlm.nih.gov/21050341
https://pubmed.ncbi.nlm.nih.gov/21050341
Publikováno v:
Vaccine. 19(4-5)
This paper describes attempts to map the location of host-protective epitopes of a recombinant vaccine antigen by assessing the ability of truncated regions of the antigen to elicit protective immune responses in sheep. Sheep were immunised with thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f717a2398268d5610c00a512544dcb
https://pubmed.ncbi.nlm.nih.gov/11027814
https://pubmed.ncbi.nlm.nih.gov/11027814
Publikováno v:
Vaccine. 18(9-10)
The immunogenicity of four synthetic peptides was investigated in sheep. The sequences of the peptides (6, 12/13, 21/22 and 24) were derived from linear, antibody-binding epitopes of the EG95 recombinant protein, a host-protective antigen of the para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13dd2b44035b67f892182ed9f6747565
https://pubmed.ncbi.nlm.nih.gov/10580190
https://pubmed.ncbi.nlm.nih.gov/10580190
Autor:
David Jenkins, Oscar Jensen, Marshall W. Lightowlers, David D. Heath, E Fernandez, D. J. Woollard, J.A Iriarte, Charles G. Gauci
Publikováno v:
International journal for parasitology. 29(4)
Experimental vaccine trials against hydatid disease have been undertaken in sheep using the EG95 recombinant vaccine. Challenge infection was with viable Echinococcus granulosus eggs obtained from a New Zealand isolate (dog/sheep cycle), an Australia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157daa175afaf3f66e790666881018c9
https://pubmed.ncbi.nlm.nih.gov/10428628
https://pubmed.ncbi.nlm.nih.gov/10428628
Publikováno v:
Parasite immunology. 20(11)
Antibody isotype and epitope specificities were examined in sheep immunized with EG95, a protective recombinant vaccine against hydatid disease. All sheep immunized with EG95 as a fusion protein with glutathione S-transferase (GST) produced prominent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0350e3e5507fe55fda25f977f59ccd53
https://pubmed.ncbi.nlm.nih.gov/9988310
https://pubmed.ncbi.nlm.nih.gov/9988310
1. The receptor subtypes through which 5-hydroxytryptamine (5-HT) increases electrolyte secretion across the mucosa of guinea-pig ileum were studied. 2. Flat sheep preparations of guinea-pig mucosa plus submucosa were placed in Ussing chambers and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261e0251c4c744e73977fd8babcd9a6b
https://europepmc.org/articles/PMC1910163/
https://europepmc.org/articles/PMC1910163/
