Výsledky vyhledávání - "D J, Wasilko"

Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core

Autor: V L, Rath, M, Ammirati, P K, LeMotte, K F, Fennell, M N, Mansour, D E, Danley, T R, Hynes, G K, Schulte, D J, Wasilko, J, Pandit

Publikováno v: Molecular cell. 6(1)

Glycogen phosphorylases catalyze the breakdown of glycogen to glucose-1-phosphate, which enters glycolysis to fulfill the energetic requirements of the organism. Maintaining control of blood glucose levels is critical in minimizing the debilitating e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6f4b80e933fc1bf6c1f0130e571db21
https://pubmed.ncbi.nlm.nih.gov/10949035

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Bisulfite or sulfite inhibits growth of Helicobacter pylori

Autor: S. J. Hawrylik, S. E. Lee, D. J. Wasilko, T. D. Gootz, S. L. Haskell

Bisulfite or sulfite was found to be inhibitory to Helicobacter pylori growth. A modified version of Brucella broth (BB), bisulfite-less BB (BLBB), supported rapid, robust, and consistent growth of H. pylori. We suggest that BLBB simply be called "Py

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec3c13eebc9a1ff1d0674e952adf16a
https://europepmc.org/articles/PMC263125/

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Vortex flow filtration of mammalian and insect cells

Autor: S. E. Lee, S. J. Hawrylik, J. B. Cheng, D. J. Wasilko, J. S. Pillar

Publikováno v: Cytotechnology. 15(1-3)

The use of vortex flow filtration for harvesting cells or conditioned medium from large scale bioreactors has proven to be an efficient, low shear method of cell concentration and conditioned medium clarification. Several 8-10 L batches of the human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7712b213c933af1dc40c88030db8b4c2
https://pubmed.ncbi.nlm.nih.gov/7765938

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Akademický článek

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.

Autor: Kim, Robbert Q.¹ (AUTHOR), Misra, Mohit^2,3,4 (AUTHOR), Gonzalez, Alexis^2,3 (AUTHOR), Tomašković, Ines^2,3 (AUTHOR), Shin, Donghyuk^2,3,5 (AUTHOR), Schindelin, Hermann⁴ (AUTHOR), Filippov, Dmitri V.⁶ (AUTHOR), Ovaa, Huib¹ (AUTHOR), Đikić, Ivan^2,3 (AUTHOR), Heden van Noort, Gerbrand J.¹ (AUTHOR) gvanderheden@lumc.nl

Publikováno v: Chemistry - A European Journal. 2/1/2021, Vol. 27 Issue 7, p2506-2512. 7p.

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Akademický článek

Chemical Tools for Probing the Ub/Ubl Conjugation Cascades.

Autor: Kochańczyk T; Structural Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, New York, 10065, USA., Fishman M; Structural Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, New York, 10065, USA., Lima CD; Structural Biology Program, Sloan Kettering Institute, 1275 York Avenue, New York, New York, 10065, USA.; Howard Hughes Medical Institute, 1275 York Avenue, New York, New York, 10065, USA.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Sep 23, pp. e202400659. Date of Electronic Publication: 2024 Sep 23.

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Akademický článek

Challenges for the Discovery of Non-Covalent WRN Helicase Inhibitors.

Autor: Heuser A; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Abdul Rahman W; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Bechter E; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Blank J; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Buhr S; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Erdmann D; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Fontana P; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Mermet-Meillon F; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Meyerhofer M; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Strang R; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Schrapp M; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Zimmermann C; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Cortes-Cros M; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Möbitz H; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland., Hamon J; Novartis Biomedical Research, Novartis Campus, CH-4056, Basel, Switzerland.

Publikováno v: ChemMedChem [ChemMedChem] 2024 Apr 16; Vol. 19 (8), pp. e202300613. Date of Electronic Publication: 2024 Mar 07.

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