Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D J, Venzon"'
Publikováno v:
Mayo Clinic Proceedings. 72:901-912
To determine the outcome of all patients with small-cell lung cancer (SCLC) treated at the US National Cancer Institute between April 1973 and April 1993.We retrospectively analyzed a series of 594 consecutive patients with SCLC treated at a single i
Autor:
V D, Corleto, B, Annibale, F, Gibril, S, Angeletti, J, Serrano, D J, Venzon, G, Delle Fave, R T, Jensen
Publikováno v:
Alimentary pharmacologytherapeutics. 15(10)
Proton pump inhibitors are potent acid suppressants which, at normal doses, can result in hypergastrinaemia in patients with idiopathic oesophageal reflux disease and in the control of symptoms in most patients with gastrinomas. Therefore, their use
Autor:
S, Sei, D P, O'Neill, S K, Stewart, Q, Yang, M, Kumagai, A M, Boler, M A, Adde, S L, Zwerski, L V, Wood, D J, Venzon, I T, Magrath
Publikováno v:
Cancer research. 61(13)
A common polymorphism in the 3' untranslated region of the stromal cell-derived factor 1 (also called pre-B-cell-stimulating factor) beta gene transcript, termed SDF1-3'A, has been associated with an increased risk of non-Hodgkin's lymphoma (NHL) in
Publikováno v:
Cancer. 85(7)
Serum chromogranin A levels (CgA) are reported by some authors to be of clinical utility for assessing the presence or absence of a pancreatic endocrine tumor and tumor extent or growth. The aim of the current study was to assess this finding and com
Autor:
Z, Zhuang, A O, Vortmeyer, S, Pack, S, Huang, T A, Pham, C, Wang, W S, Park, S K, Agarwal, L V, Debelenko, M, Kester, S C, Guru, P, Manickam, S E, Olufemi, F, Yu, C, Heppner, J S, Crabtree, M C, Skarulis, D J, Venzon, M R, Emmert-Buck, A M, Spiegel, S C, Chandrasekharappa, F S, Collins, A L, Burns, S J, Marx, I A, Lubensky
Publikováno v:
Cancer research. 57(21)
Gastrinomas and insulinomas are frequent in multiple endocrine neoplasia type 1 (MEN1). The MEN1 tumor suppressor gene was recently identified. To elucidate the etiological role of the MEN1 gene in sporadic enteropancreatic endocrine tumorigenesis, w
Autor:
A, Thibault, D, Samid, A C, Tompkins, W D, Figg, M R, Cooper, R J, Hohl, J, Trepel, B, Liang, N, Patronas, D J, Venzon, E, Reed, C E, Myers
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(3)
Lovastatin, an inhibitor of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (the major regulatory enzyme of the mevalonate pathway of cholesterol synthesis), displays antitumor activity in experimental models. We therefore conducted a Phas
Autor:
J A, O'Shaughnessy, D J, Venzon, M, Gossard, M H, Noone, A, Denicoff, A, Tolcher, D, Danforth, J, Jacobson, P, Keegan, L, Miller, C, Chow, B, Goldspiel, K H, Cowan
Publikováno v:
Blood. 86(8)
Cumulative thrombocytopenia is a dose-limiting toxicity of dose-intensive chemotherapy for advanced breast cancer. In this phase I study, we have studied the hematologic toxicity associated with sequential interleukin-3 (IL-3) and granulocyte-macroph
Autor:
A, Thibault, D, Samid, M R, Cooper, W D, Figg, A C, Tompkins, N, Patronas, D J, Headlee, D R, Kohler, D J, Venzon, C E, Myers
Publikováno v:
Cancer. 75(12)
The growth-inhibiting and differentiating effects of sodium phenylacetate against hematopoietic and solid tumor cell lines has aroused clinical interest in its use as an anticancer drug. In an earlier Phase I trial of phenylacetate aimed at maintaini
Autor:
A, Thibault, M R, Cooper, W D, Figg, D J, Venzon, A O, Sartor, A C, Tompkins, M S, Weinberger, D J, Headlee, N A, McCall, D, Samid
Publikováno v:
Cancer research. 54(7)
Phenylacetate has recently been shown to suppress tumor growth and promote differentiation in experimental models. A phase I trial of phenylacetate was conducted in 17 patients with advanced solid tumors. Each patient received a single i.v. bolus dos
Publikováno v:
Archives of internal medicine. 153(3)
Design of a cost-effective algorithm for staging disease in patients with small-cell lung cancer.An algorithm was constructed by analyzing all permutations of a sequence of procedures required to stage disease in patients with small-cell lung cancer.