Výsledky vyhledávání - "D J, Snyders"

Effects of a quaternary bupivacaine derivative on delayed rectifier K(+) currents

Autor: M, Longobardo, T, González, R, Navarro-Polanco, R, Caballero, E, Delpón, J, Tamargo, D J, Snyders, M M, Tamkun, C, Valenzuela

Publikováno v: British journal of pharmacology. 130(2)

Block of hKv1.5 channels by R-bupivacaine has been attributed to the interaction of the charged form of the drug with an intracellular receptor. However, bupivacaine is present as a mixture of neutral and charged forms both extra- and intracellularly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e03319f5bcc4348986c33bf2fbfe266c
https://pubmed.ncbi.nlm.nih.gov/10807678

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Ibutilide, a methanesulfonanilide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. Concentration-, time-, voltage-, and use-dependent effects

Autor: T, Yang, D J, Snyders, D M, Roden

Publikováno v: Circulation. 91(6)

Ibutilide is an action potential-prolonging antiarrhythmic currently in clinical trials. The drug shares structural similarities with E-4031 and dofetilide, specific blockers of the rapidly activating delayed rectifier K+ current (IKr). However, prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c23c6f4d8b1483703fd47aa7236e94fd
https://pubmed.ncbi.nlm.nih.gov/7586381

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Modification of cardiac pace-maker current by 4-aminopyridine [proceedings]

Autor: D J, Snyders, P P, van Bogaert

Publikováno v: Archives internationales de physiologie et de biochimie. 86(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07aa55efa914bd335cfcfae098ed58fc
https://pubmed.ncbi.nlm.nih.gov/80181

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Drug associated sodium channels inactivate and reactivate at more negative potentials than drug-free channels

Autor: D J, Snyders, L M, Hondeghem

Publikováno v: Proceedings of the Western Pharmacology Society. 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9374b823a2d934ef84d609054868c95
https://pubmed.ncbi.nlm.nih.gov/2442767

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Computer model of cardiac pace-maker currents

Autor: P P, Van Bogaert, D J, Snyders, E P, Hontelé

Publikováno v: Archives internationales de physiologie et de biochimie. 84(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::691e2d8359bfa30400e4e3598162095c
https://pubmed.ncbi.nlm.nih.gov/64145

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