Zobrazeno 1 - 8
of 8
pro vyhledávání: '"D J, Rieman"'
Autor:
David E. Fisher, D. J. Rieman, Gabriela Motyckova, D. Z. Fisher, Martin A. Horstmann, Katherine N. Weilbaecher
Publikováno v:
Proceedings of the National Academy of Sciences. 98:5798-5803
Various genetic conditions produce dysfunctional osteoclasts resulting in osteopetrosis or osteosclerosis. These include human pycnodysostosis, an autosomal recessive syndrome caused by cathepsin K mutation, cathepsin K-deficient mice, and mitf mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4d6c6f981b5eb2b620f4ff81ffd53ac
https://doi.org/10.1073/pnas.091479298
https://doi.org/10.1073/pnas.091479298
Autor:
W P, Prichett, A J, Patton, J A, Field, K A, Brun, J G, Emery, K B, Tan, D J, Rieman, H A, McClung, D P, Nadeau, J L, Mooney, L J, Suva, M, Gowen, M E, Nuttall
Publikováno v:
Journal of cellular biochemistry. 76(4)
Bipotential cells in human trabecular bone explant cultures that express osteoblast characteristics are able to undergo adipogenesis in the presence of 3-isobutyl-1-methylxanthine plus dexamethasone (Nuttall et al. [1998] J Bone Miner Res 13:371-382)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b0ace77cae13532dbf48eb225a3bab7
https://pubmed.ncbi.nlm.nih.gov/10653983
https://pubmed.ncbi.nlm.nih.gov/10653983
Autor:
A M, Badger, D E, Griswold, R, Kapadia, S, Blake, B A, Swift, S J, Hoffman, G B, Stroup, E, Webb, D J, Rieman, M, Gowen, J C, Boehm, J L, Adams, J C, Lee
Publikováno v:
Arthritis and rheumatism. 43(1)
To evaluate the effects of SB 242235, a potent and selective inhibitor of p38 mitogen-activated protein (MAP) kinase, on joint integrity in rats with adjuvant-induced arthritis (AIA).Male Lewis rats with AIA were orally treated either prophylacticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28d8da33d21c5a49a61fd11c1c58292d
https://pubmed.ncbi.nlm.nih.gov/10643714
https://pubmed.ncbi.nlm.nih.gov/10643714
Autor:
A M, Badger, S M, Blake, R A, Dodds, D E, Griswold, B A, Swift, D J, Rieman, G B, Stroup, S J, Hoffman, M, Gowen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(3)
Idoxifene, a selective estrogen receptor modulator, was evaluated in male and female rats with adjuvant-induced arthritis (AA). AA was induced in Lewis rats with Mycobacterium butyricum in paraffin oil injected into the base of the tail, and the anim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::753d9dc7b8fc32959a6bd141a50da63e
https://pubmed.ncbi.nlm.nih.gov/10565864
https://pubmed.ncbi.nlm.nih.gov/10565864
Autor:
M W, Lark, G B, Stroup, S M, Hwang, I E, James, D J, Rieman, F H, Drake, J N, Bradbeer, A, Mathur, K F, Erhard, K A, Newlander, S T, Ross, K L, Salyers, B R, Smith, W H, Miller, W F, Huffman, M, Gowen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
The Arg-Gly-Asp (RGD)-binding integrin alpha(V)beta(3) is highly expressed on osteoclasts and has been proposed to mediate cell-matrix adhesion required for osteoclast-mediated bone resorption. Antagonism of this receptor should prevent stable osteoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c265c9c299af6bb5e141179d3d2de53
https://pubmed.ncbi.nlm.nih.gov/10525079
https://pubmed.ncbi.nlm.nih.gov/10525079
Publikováno v:
Oncology research. 4(4-5)
Over 4,500 natural product extracts were screened for their abilities to inhibit binding of radiolabeled TGF-alpha to A431 cells; several plant extracts were identified as potential leads with IC50 values of less than 30 micrograms/mL. The active com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9299b980e02b3e1d875a3fb3e2f65a3c
https://pubmed.ncbi.nlm.nih.gov/1324032
https://pubmed.ncbi.nlm.nih.gov/1324032
Autor:
R D, Woessner, W K, Eng, G A, Hofmann, D J, Rieman, F L, McCabe, R P, Hertzberg, M R, Mattern, K B, Tan, R K, Johnson
Publikováno v:
Oncology research. 4(11-12)
A subline of P388 leukemia made 10-fold resistant to camptothecin (CPT) by serial passage in drug-treated mice was adapted to growth in tissue culture and made hyper-resistant to CPT by passage in the presence of increasing concentrations of the drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4844eab3b0692c07e775249a361df698
https://pubmed.ncbi.nlm.nih.gov/1338578
https://pubmed.ncbi.nlm.nih.gov/1338578
Publikováno v:
Journal of Medicinal Chemistry. 31:1762-1767
The synthesis and testing of potential multisubstrate inhibitors of tyrosine-specific protein kinases are described. One of the substrates, ATP, was mimicked by the known kinase inhibitor 5'-[4-(fluorosulfonyl)benzoyl]adenosine, which was covalently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b2ec215f6e11da7ace3b48c53472f4
https://doi.org/10.1021/jm00117a015
https://doi.org/10.1021/jm00117a015