Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D J, Hunting"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 80:650-653
Ultraviolet (UV) radiation is a strong apoptotic trigger in many cell types. We have previously reported that a plant amino acid, mimosine (-(N-(3-hydroxy-4-pyridone))--aminopropionic acid), with a well-known reversible G1 cell cycle arrest activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556834d5ac39bda0f5b8730b9a68f07d
https://doi.org/10.1139/y02-075
https://doi.org/10.1139/y02-075
Autor:
G. Larone, D. J. Hunting
Publikováno v:
Journal de Chimie Physique. 88:1095-1104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f75a7c1bc96489b64676d131a255e15
https://doi.org/10.1051/jcp/1991881095
https://doi.org/10.1051/jcp/1991881095
Autor:
N Bissonnette, D J Hunting
Publikováno v:
Oncogene. 16(26)
Cells expressing the R273H mutant of p53, which lacks sequence specific DNA binding capacity, do not undergo cell cycle arrest in G1 following exposure to ionizing or UV radiation because of their inability to induce p21Waf1/Cip1, a cyclin-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839f82531618c8f3f2cb2330cb13e8df
https://pubmed.ncbi.nlm.nih.gov/9692554
https://pubmed.ncbi.nlm.nih.gov/9692554
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 75(4)
Previous studies have shown that the apoptotic response of cells following DNA damage requires p53 expression. Wild-type p53 protein levels increase in response to DNA damage and its growth-suppressive action is thought to be mediated by transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb88fddc20c51719a680948226927072
https://pubmed.ncbi.nlm.nih.gov/9493957
https://pubmed.ncbi.nlm.nih.gov/9493957
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 75(4)
The oxidation of cytosine in DNA by free radicals and other oxidants leads to an assortment of products including pyrimidine ring 5,6-saturated, 5,6-unsaturated, contraction, and fragmentation products. The formation of these products in cellular DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45e1a458d2270b465f33f969b72ade42
https://pubmed.ncbi.nlm.nih.gov/9493960
https://pubmed.ncbi.nlm.nih.gov/9493960
Autor:
G. de Murcia, J M De Murcia, B. J. Gowans, Valérie Schreiber, D Grunwald, Carlotta Trucco, D. J. Hunting
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(11)
Poly(ADP-ribose) polymerase [PARP; NAD+ ADP-ribosyltransferase; NAD+:poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyltransferase, EC 2.4.2.30] is a zinc-dependent eukaryotic DNA-binding protein that specifically recognizes DNA strand brea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951a7f3a2a30cb01521fcc38792a9e7c
https://pubmed.ncbi.nlm.nih.gov/7761396
https://pubmed.ncbi.nlm.nih.gov/7761396
Publikováno v:
International journal of radiation biology. 66(6)
Photoirradiation of aqueous solutions of DNA in the presence of Al- or Zn-tetrasulphonated phthalocyanines (AIPcS4 and ZnPcS4) causes formation of strand breaks and liberation of nucleobases. The effect of added D2O, which enhances singlet oxygen (1O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f75a029f441492631fb6b62876c260e9
https://pubmed.ncbi.nlm.nih.gov/7814970
https://pubmed.ncbi.nlm.nih.gov/7814970
Publikováno v:
Journal of Physical Chemistry B; Jul2015, Vol. 119 Issue 30, p9496-9500, 5p
Publikováno v:
DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells ISBN: 9781468413298
The DNA excision repair process involves transient changes in chromatin structure at the nucleosomal level (Smerdon and Lieberman, 1978; Smerdon, et al., 1978; Tlsty and Lieberman, 1978; Smerdon, et al., 1979; Oleson, et al., 1979; Smerdon and Lieber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec4ad80b5a8d997150be056bd64d4939
https://doi.org/10.1007/978-1-4684-1327-4_30
https://doi.org/10.1007/978-1-4684-1327-4_30
Publikováno v:
Molecular pharmacology. 28(2)
The effects of inhibitors of poly(ADP-ribose) synthesis on cell growth and several parameters of nucleotide metabolism have been determined. At concentrations which produced similar inhibitions of poly(ADP-ribose) synthesis, 3-acetylaminobenzamide (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e82f074b47fc1961efa74fd59595857e
https://pubmed.ncbi.nlm.nih.gov/2991739
https://pubmed.ncbi.nlm.nih.gov/2991739