Výsledky vyhledávání

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

Autor: L S Park, D. J. Friend, R. DuBose, Dirk M. Anderson, K. Shanebeck, J. G. Giri, M Ahdieh, A. Loomis, David Cosman, S Kumaki

Publikováno v: The EMBO Journal. 14:3654-3663

Interleukin-15 (IL-15) is a novel cytokine of the four-helix bundle family which shares many biological activities with IL-2, probably due to its interaction with the IL-2 receptor beta and gamma (IL-2R beta and gamma c) chains. We report here the ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e0a17cf3352f5d18ca759faed36e0b
https://doi.org/10.1002/j.1460-2075.1995.tb00035.x

Zobrazit plný text záznamu

Identification of a novel low-affinity receptor for human interleukin-7

Autor: R J, Armitage, S F, Ziegler, D J, Friend, L S, Park, W C, Fanslow

Publikováno v: Blood. 79:1738-1745

Human recombinant interleukin-7 (IL-7) was labeled with biotin and used to examine IL-7 receptor (IL-7R) expression and regulation on human primary hematopoietic cells, the monocytoid line THP1, and a range of B- and pre-B-celi lines by flow cytometr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdd8cc5c1fe433c152a6c0bcc70d334
https://doi.org/10.1182/blood.v79.7.1738.bloodjournal7971738

Zobrazit plný text záznamu

Oncostatin M and leukemia inhibitory factor trigger overlapping and different signals through partially shared receptor complexes

Autor: B, Thoma, T A, Bird, D J, Friend, D P, Gearing, S K, Dower

Publikováno v: The Journal of biological chemistry. 269(8)

Leukemia inhibitory factor (LIF) and oncostatin M (OSM) both bind to the same receptor with high affinity and thus mediate an overlapping spectrum of biological activities, the signal transduction mechanisms for which are unclear. We show that mitoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed259605c403cd6421b3509639bf7c98
https://pubmed.ncbi.nlm.nih.gov/8119965

Zobrazit plný text záznamu

Murine interleukin 7 (IL-7) receptor. Characterization on an IL-7-dependent cell line

Autor: A E Schmierer, A E Namen, D J Friend, Linda S. Park, Steven K. Dower

Publikováno v: The Journal of Experimental Medicine

A murine cell line (IxN/2b) absolutely dependent upon exogenous IL-7 for continued growth has been obtained that expresses lymphoid precursor and class I MHC antigens and also contains a rearranged mu heavy chain. This cell line has been used to defi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9153b4e4c06517f560421d2f0b6dfc1d
https://pubmed.ncbi.nlm.nih.gov/2324686

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání