Zobrazeno 1 - 10
of 22
pro vyhledávání: '"D J, Franks"'
Autor:
Cynthia, Brewer, Fanny, Bonin, Paula, Bullock, Marie-Christine, Nault, Jennifer, Morin, Sophie, Imbeault, T Y, Shen, D J, Franks, Steffany A L, Bennett
Publikováno v:
Journal of neurochemistry. 82(6)
The pro-inflammatory lipid mediator platelet activating factor (PAF: 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) accumulates in ischemia, epilepsy, and human immunodeficiency virus-1-associated dementia and is implicated in neuronal loss. The pre
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 76(1)
We have previously shown that protein kinase C (PKC) is involved in the mitogenic response of T51B cells to epidermal growth factor. In fact, epidermal growth factor was an excellent mitogen, even after prolonged pretreatment of cells with TPA, sugge
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 72(4)
Hepatocytes from mice fed griseofulvin (GF) for 8 months form Mallory bodies (MBs), which represent a pathologic state of intermediate filaments (IFs). The cellular mechanisms that lead to MB formation are not known.This study was aimed to investigat
Publikováno v:
Receptorschannels. 2(1)
In this paper we demonstrate the existence of specific, high affinity 17-beta estradiol binding in MDBK cells (a normal non-transformed renal cell line). Scatchard analysis revealed binding characteristics typical of the estrogen receptor (ER). Only
Autor:
Y H, Kim, D J, Franks
Publikováno v:
Orthopaedic review. 21(3)
A revision technique of the failed cemented femoral stem was developed using a standard cementless porous-coated prosthesis. The advantages of this technique are that the prosthesis has apposition to autogenic bone rather than allograft; problems of
Publikováno v:
Canadian Journal of Biochemistry and Cell Biology. 61:1158-1165
Incubation of intact platelets with prostaglandins (PGE1 and PGI2) and phosphodiesterase inhibitors (1-methyl-3-isobutyl-xanthine, indomethacin, dipyridamol) lead to activation of cAMP phosphodiesterase. The activation was rapid (maximal within 30 s)
Publikováno v:
Biochemical and Biophysical Research Communications. 44:1177-1183
Summary Prostaglandin A 1 and E 1 , but not F 1 α or F 2 α , stimulate thymic lymphocyte adenylate cyclase with resultant increases in the intracellular level of cyclic AMP and the rate of cell proliferation. A possible mechanism of action of the p
Publikováno v:
Experimental Biology and Medicine. 137:453-457
Publikováno v:
Journal of cyclic nucleotide research. 8(2)
The stimulation of adenylate cyclase by various exogenous proteases has been described in several tissues. In this study, we describe a 2 to 7-fold increase of adenylate cyclase activity in a particulate preparation from rat platelets following prior
Publikováno v:
Clinical and investigative medicine. Medecine clinique et experimentale. 8(1)
Abnormalities in the regulation of proliferation of vascular smooth muscle are believed to be involved in the development of atherosclerosis. This study addresses the question of whether altered levels or activity of circulating factors in diabetes m