Zobrazeno 1 - 10
of 10
pro vyhledávání: '"D I Papac"'
Publikováno v:
The Journal of Immunology. 157:198-206
Matrix-assisted laser desorption mass spectrometry in combination with proteolytic protection assays has been used to identify the functional epitope on HIV-1 IIIB p26 recognized by a mAb. In this procedure, the intact protein is affinity bound to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3001aee6220faea554273a5de188bfbf
https://doi.org/10.4049/jimmunol.157.1.198
https://doi.org/10.4049/jimmunol.157.1.198
Autor:
D I, Papac, Z, Shahrokh
Publikováno v:
Pharmaceutical research. 18(2)
This review highlights the many roles mass spectrometry plays in the discovery and development of new therapeutics by both the pharmaceutical and the biotechnology industries. Innovations in mass spectrometer source design, improvements to mass accur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d43c116f8e66492c688fe7e7cf2f58e
https://pubmed.ncbi.nlm.nih.gov/11405282
https://pubmed.ncbi.nlm.nih.gov/11405282
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(1)
Matrix-assisted laser desorption mass spectrometry in combination with proteolytic protection assays has been used to identify the functional epitope on HIV-1 IIIB p26 recognized by a mAb. In this procedure, the intact protein is affinity bound to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b37494e715d6b3388d46ad18f8375d22
https://pubmed.ncbi.nlm.nih.gov/8683115
https://pubmed.ncbi.nlm.nih.gov/8683115
Autor:
Jeffrey Lockman, R. Gordillo, Robert O. Carlson, Vijay Baichwal, Chad Bradford, G. G. Mather, B. R. Murphy, J.A. Willardsen, T. C. Fleischer, D. I. Papac
Publikováno v:
Journal of Clinical Oncology. 29:10529-10529
10529 Background: MPC‐9528 is a potent, selective, orally bioavailable inhibitor of nicotinamide phosphoribosyltransferase (Nampt) that catalyzes the rate-limiting step in NAD biosynthesis from nic...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10951dec2cfd413f4ed73db6c5254f01
https://doi.org/10.1200/jco.2011.29.15_suppl.10529
https://doi.org/10.1200/jco.2011.29.15_suppl.10529
Publikováno v:
Journal of Clinical Oncology. 29:e13016-e13016
e13016 Background: MPC-3100, an orally bioavailable synthetic inhibitor of HSP90, has demonstrated efficacy in animal models and is currently in a phase I clinical study in cancer patients. Toxicol...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b56af439108c6ab08dd0b2bab9b19a49
https://doi.org/10.1200/jco.2011.29.15_suppl.e13016
https://doi.org/10.1200/jco.2011.29.15_suppl.e13016
Publikováno v:
Journal of Clinical Oncology. 29:e13019-e13019
e13019 Background: MPC-3100 is an oral synthetic inhibitor of HSP90, in a phase I safety study in cancer patients. Major cytochrome P450 (CYP450) and UDP-glucuronosyltransferase (UGT) isozymes were...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526d7dc62417c45b1b8769dffd1c1c81
https://doi.org/10.1200/jco.2011.29.15_suppl.e13019
https://doi.org/10.1200/jco.2011.29.15_suppl.e13019
Autor:
Robert O. Carlson, D. I. Papac, K. H. Zavitz, Vijay Baichwal, G. G. Mather, Leslie Reeves, Andrew P. Beelen, Chad Bradford, J. T. Jones
Publikováno v:
Journal of Clinical Oncology. 29:e13080-e13080
e13080 Background: MPC-6827 is a small molecule microtubule disrupting agent that is being evaluated in phase II studies for the treatment of glioblastoma multiforme. It crosses the blood-brain bar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e70ec4aa8982c352231347ecc778e8eb
https://doi.org/10.1200/jco.2011.29.15_suppl.e13080
https://doi.org/10.1200/jco.2011.29.15_suppl.e13080
Autor:
Jeffrey Lockman, J. Jay Boniface, Ryan T. Terry-Lorenzo, J.A. Willardsen, R.O. Carlson, V.R. Baichwal, J.P. Green, W.R. Judd, L. DeMie, D. I. Papac
Publikováno v:
European Journal of Cancer Supplements. 8:4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d236253b9a4c00837e75f914944939d3
https://doi.org/10.1016/s1359-6349(10)71702-x
https://doi.org/10.1016/s1359-6349(10)71702-x
Publikováno v:
The Journal of biological chemistry. 267(24)
Bovine rhodopsin has been reported to be S-palmitylated at cysteines 322 and 323 (Ovchinnikov, Y. A., Abdulaev, N. G., and Bogachuk, A.S. (1988) FEBS Lett. 230, 1-5). Using a combination of enzymatic and chemical cleavage techniques in conjunction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7c732f66181beaf5e5ef9519b329b8d
https://pubmed.ncbi.nlm.nih.gov/1512231
https://pubmed.ncbi.nlm.nih.gov/1512231
Autor:
D I, Papac, M R, Franklin
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(2)
The effects of N-benzylimidazole on hepatic microsomal and cytosolic drug-metabolizing enzymes were compared to the effects produced by phenobarbital, beta-naphthoflavone, a polycyclic aromatic hydrocarbon, and Aroclor 1254, a polychlorinated bipheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04ef2e2da5d6d23edab819538ab5f4ed
https://pubmed.ncbi.nlm.nih.gov/2898344
https://pubmed.ncbi.nlm.nih.gov/2898344