Zobrazeno 1 - 10
of 36
pro vyhledávání: '"D I, Watkins"'
Autor:
J, Sidney, J L, Dzuris, M J, Newman, R P, Johnson, A, Kaur, K, Amitinder, C M, Walker, E, Appella, B, Mothe, D I, Watkins, A, Sette
Publikováno v:
The Journal of Immunology. 165:6387-6399
Single amino acid substitution analogs of the known Mamu A*01 binding peptide gag 181-190 and libraries of naturally occurring sequences of viral or bacterial origin were used to rigorously define the peptide binding motif associated with Mamu A*01 m
Publikováno v:
The Journal of Immunology. 159:3311-3321
Maternal tolerance of the fetal allograft remains poorly understood. In humans, expression of the highly polymorphic classical HLA-A and HLA-B loci is suppressed, while expression of the nonclassical HLA-G locus is up-regulated at the maternal-fetal
Publikováno v:
The Journal of Immunology. 157:5428-5437
HLA-G is a nonclassical MHC class I molecule that is primarily expressed in the placenta. To investigate whether rhesus monkeys possess an HLA-G ortholog, we cloned and sequenced MHC class I cDNAs from the rhesus placenta. We identified two rhesus MH
Publikováno v:
The Journal of Immunology. 154:2516-2522
In light of the importance of virus-specific CTL in the control of the spread of the AIDS virus, it will be important to assess the generation of these effector cell responses in trials of novel vaccine strategies for the prevention of AIDS virus inf
Publikováno v:
The Journal of Immunology. 148:2547-2554
To investigate whether the classical HLA MHC class I loci have been preserved during evolution of the primates, we have cloned, sequenced, and expressed eight MHC class I cDNA from orangutan and gibbon lymphocytes. Both the HLA-A and -B loci are pres
Publikováno v:
The Journal of Immunology. 147:320-329
Infection of macaque monkeys with the simian immunodeficiency virus of macaques (SIVmac) results in disease similar to human AIDS. Therefore, the macaque monkey is proving to be an important model for testing the effectiveness of various AIDS vaccine
Autor:
H Yamamoto, M D Miller, D I Watkins, G B Snyder, N E Chase, G P Mazzara, L Gritz, D L Panicali, N L Letvin
Publikováno v:
The Journal of Immunology. 145:3740-3746
The relative contributions of the effector lymphocyte responses to the AIDS virus envelope glycoprotein (env) were explored in simian immunodeficiency virus of macaques (SIVmac)-infected rhesus monkeys. CD8+, MHC class I-restricted, env-specific CTL
Publikováno v:
The Journal of Immunology. 145:3483-3490
MHC class I glycoproteins are highly diverse in most species. The Syrian hamster has long been thought to express monomorphic MHC class I molecules and thus be an exception to this rule. Here we show that Syrian hamsters express diverse MHC class I g
Publikováno v:
The Journal of Immunology. 144:3726-3735
The cotton-top tamarin (Saguinus oedipus) is a naturally occurring "A" + "B"----"A" bone marrow-chimeric species. These primates usually are born as dizygotic twins and, due to placental vascular anastomoses, develop sharing each others' bone marrow
Publikováno v:
The Journal of Immunology. 144:1136-1143
To investigate the evolutionary pressures that drive the generation of polymorphism in primate MHC class I molecules, three cDNA that encode MHC class I alleles from a New World monkey, the cotton-top tamarin (Saguinus oedipus), were cloned and seque