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Publikováno v:
Blood. 83:2057-2062
Members of the Notch gene family have been shown to mediate cell-fate decisions by multipotent precursors in a number of different systems. To determine whether members of this family might play a similar role in hematopoiesis, we asked if homologues
Autor:
D M, Bodine, T, Moritz, R E, Donahue, B D, Luskey, S W, Kessler, D I, Martin, S H, Orkin, A W, Nienhuis, D A, Williams
Publikováno v:
Blood. 82:1975-1980
Retroviral mediated gene transfer into stem cells has been proposed as therapy for many inherited hematopoietic diseases. Deficiency of the enzyme adenosine deaminase (ADA) results in depletion of T lymphocytes, causing severe combined immunodeficien
Publikováno v:
Genesdevelopment. 14(8)
We have investigated the mechanism, structural correlates, and cis-acting elements involved in chromatin opening and gene activation, using the human beta-globin locus as a model. Full transcriptional activity of the human beta-globin locus requires
Autor:
Fujiwara‐Igarashi, Aki1 (AUTHOR) afjig@nvlu.ac.jp, Ohshima, Takafumi1 (AUTHOR), Kojima, Ryusei1 (AUTHOR), Fujita, Michio1 (AUTHOR), Nakazawa, Yuta1 (AUTHOR)
Publikováno v:
Veterinary Medicine & Science. May2024, Vol. 10 Issue 3, p1-12. 12p.
Autor:
Marcelino de Oliveira, Katarina1 nutrikatarinamarcelino@gmail.com, Lourenço Costa, Vanessa Vieira1 vanessacosta@ufpa.br, Lopes Gomes, Daniela1 danielagomes@ufpa.br, de Souza Figueira, Marcela1 msfigueira@ufpa.br
Publikováno v:
Revista Brasileira de Obesidade, Nutrição e Emagrecimento. mar/abr2024, Vol. 18 Issue 113, p266-274. 9p.
Autor:
Hare, Kathleen1 (AUTHOR), Moore, Amber2 (AUTHOR) amberjanellemoore@gmail.com
Publikováno v:
Journal of Experiential Education. Mar2024, Vol. 47 Issue 1, p135-157. 23p.
Enhancer elements have been shown to affect the probability of a gene establishing an active transcriptional state and suppress the silencing of reporter genes in cell lines, but their effect in transgenic mice has been obscured by the use of assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f1336b6d85d20294ce3eed2ea61a06
https://europepmc.org/articles/PMC231886/
https://europepmc.org/articles/PMC231886/
Publikováno v:
Experimental hematology. 24(3)
AP-1/NF-E2 motifs found in erythroid transcription control elements are associated with powerful transcription activation and thought to be regulated by the erythroid transcription factor NF-E2. We have studied AP-1/NF-E2 motifs from three different
Publikováno v:
Blood. 85(11)
Murine embryonic stem cells are able to differentiate into embryoid bodies (EBs) in vitro in the absence of leukemia-inhibitory factor with the formation of different types of hematopoietic precursors within these EBs. With the aim of determining the