Zobrazeno 1 - 10
of 2 263
pro vyhledávání: '"D Horton"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract The mitochondrial permeability transition pore (mPTP) is a supramolecular channel that regulates exchange of solutes across cristae membranes, with executive roles in mitochondrial function and cell death. The contribution of the mPTP to nor
Externí odkaz:
https://doaj.org/article/78f219f0a4bf441992584c62eb6530b0
Autor:
Oscar F. Borja-Montes, Alejandro Toro-Pedroza, Darrell D. Horton, Leslie A. Andritsos, Ala Ebaid
Publikováno v:
European Journal of Case Reports in Internal Medicine (2024)
Background: Warm autoimmune haemolytic anaemia (wAIHA) is an acquired haemolytic disorder most commonly treated with a combination of corticosteroids, rituximab and/or splenectomy. Third-line therapies for refractory cases include immunosuppressive a
Externí odkaz:
https://doaj.org/article/5bbc70df3797454db8c6268b3ba5c24b
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109517- (2024)
Summary: Both humans and mice with congenital generalized lipodystrophy due to AGPAT2 deficiency develop diabetes mellitus, insulin resistance, and hepatic steatosis, which have been attributed to the near total loss of adipose tissue (AT). Here, we
Externí odkaz:
https://doaj.org/article/3b46cd7f3a354f9a9e35118f7af216af
Autor:
Anil K. Agarwal, Katie Tunison, Goncalo Vale, Jeffrey G. McDonald, Xilong Li, Jay D. Horton, Abhimanyu Garg
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108653- (2024)
Summary: AGPAT2, a critical enzyme involved in the biosynthesis of phospholipids and triacylglycerol (TAG), is highly expressed in adipose tissue (AT). Whether overexpression of AGPAT2 in AT will result in increased TAG synthesis (obesity) and its me
Externí odkaz:
https://doaj.org/article/380c5aacd5c3490d8b8b1f8961965494
Autor:
Anil K. Agarwal, Katie Tunison, Goncalo Vale, Jeffrey G. McDonald, Xilong Li, Philipp E. Scherer, Jay D. Horton, Abhimanyu Garg
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107806- (2023)
Summary: Genetic loss of Agpat2 in humans and mice results in congenital generalized lipodystrophy with near-total loss of adipose tissue and predisposition to develop insulin resistance, diabetes mellitus, hepatic steatosis, and hypertriglyceridemia
Externí odkaz:
https://doaj.org/article/cbfdbaa2bfeb492e96fa08ae536cb1d7
Autor:
Chaochao Dun, Sichi Li, Linfeng Chen, Robert D. Horton, Mark D. Allendorf, Brandon C. Wood, Vitalie Stavila, Jeffrey J. Urban
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Metal amides are attractive candidates for hydrogen storage due to their high volumetric and gravimetric hydrogen densities. However, the sluggish kinetics and competing side reactions during hydrogen uptake and release limit their practical
Externí odkaz:
https://doaj.org/article/49a25fa8c56246988c9f4aa5be05f4e4
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 11 (2023)
We present a case report of a 56-year-old woman who was diagnosed with biopsy-proven left thalamic glioblastoma multiforme (GBM). She was treated with standard concurrent chemotherapy and radiation, as well as a 2-year period of adjuvant temozolomide
Externí odkaz:
https://doaj.org/article/d0f05dd8da904cfd827db3799e9f0a6d
Autor:
Aaron D. Horton
Part sport, part performance art, professional wrestling's appeal crosses national, racial and gender boundaries--in large part by playing to national, racial and gender stereotypes that resonate with audiences. Scholars who study competitive sports
Autor:
Amina Mohammadalipour, Miguel F. Diaz, Megan Livingston, Adesuwa Ewere, Allen Zhou, Paulina D. Horton, Loretta T. Olamigoke, John M. Lamar, John P. Hagan, Hyun J. Lee, Pamela L. Wenzel
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 5, Pp 342-361 (2022)
Abstract Lymphatic drainage generates force that induces prostate cancer cell motility via activation of Yes‐associated protein (YAP), but whether this response to fluid force is conserved across cancer types is unclear. Here, we show that shear st
Externí odkaz:
https://doaj.org/article/2299162a00be43be9430cd3a82655823
Autor:
Xiaorong Fu, Stanisław Deja, Justin A. Fletcher, Norma N. Anderson, Monika Mizerska, Gonçalo Vale, Jeffrey D. Browning, Jay D. Horton, Jeffrey G. McDonald, Matthew A. Mitsche, Shawn C. Burgess
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Fat synthesis is necessary for normal physiology, but its dysregulation contributes to the pathology of many diseases. Here, the authors report a high-resolution mass spectrometry approach that quantifies fat synthesis flux in humans and mice followi
Externí odkaz:
https://doaj.org/article/b1cab25a3bac4392a10db218cc30d323