Zobrazeno 1 - 10
of 787
pro vyhledávání: '"D Hickman"'
Autor:
Caleb Ferguson, Fahad Shaikh, Annie Downie, Tonia Wilson, Kaitlyn Griffin, Sabine M. Allida, Louise D. Hickman, Beata V. Bajorek, Rochelle Wynne
Publikováno v:
BMC Digital Health, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Background There are many unmet educational needs for people living with atrial fibrillation (AF). Digital health offers promise; however, evidence is largely lacking. Hence, the objective of this study was to determine the system usability,
Externí odkaz:
https://doaj.org/article/4b4838ca6c264865ab6b1cf53c6c4583
Autor:
Christine E Nelson, Taylor W Foreman, Eduardo R Fukutani, Keith D Kauffman, Shunsuke Sakai, Joel D Fleegle, Felipe Gomez, NIAID/DIR Tuberculosis Imaging Program, Sydnee T Gould, Cyril Le Nouën, Xueqiao Liu, Tracey L Burdette, Nicole L Garza, Bernard A P Lafont, Kelsie Brooks, Cecilia S Lindestam Arlehamn, Daniela Weiskopf, Alessandro Sette, Heather D Hickman, Ursula J Buchholz, Reed F Johnson, Jason M Brenchley, James P Oberman, Artur T L Quieroz, Bruno B Andrade, Laura E Via, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012339 (2024)
The regulation of inflammatory responses and pulmonary disease during SARS-CoV-2 infection is incompletely understood. Here we examine the roles of the prototypic pro- and anti-inflammatory cytokines IFNγ and IL-10 using the rhesus macaque model of
Externí odkaz:
https://doaj.org/article/4f2fca22c4d14a298492237eba187e8e
Publikováno v:
Learning Health Systems, Vol 8, Iss 2, Pp n/a-n/a (2024)
Abstract Introduction Rapid translation of research findings into clinical practice through innovation is critical to improve health systems and patient outcomes. Access to efficient systems of learning underpinned with real‐time data are the futur
Externí odkaz:
https://doaj.org/article/1db11dcb485f4261abf480c03d74bc29
Autor:
Autumn C. Holmes, Cormac J. Lucas, Morgan E. Brisse, Brian C. Ware, Heather D. Hickman, Thomas E. Morrison, Michael S. Diamond
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113876- (2024)
Summary: Alphaviruses are mosquito-transmitted pathogens that induce high levels of viremia, which facilitates dissemination and vector transmission. One prevailing paradigm is that, after skin inoculation, alphavirus-infected resident dendritic cell
Externí odkaz:
https://doaj.org/article/dd85bfbcd96b40e78b5375c2d78a42f8
Autor:
Chad H. Hogan, Shana M. Owens, Glennys V. Reynoso, Yifei Liao, Thomas J. Meyer, Monika A. Zelazowska, Bin Liu, Xiaofan Li, Anna K. Grosskopf, Camille Khairallah, Varvara Kirillov, Nancy C. Reich, Brian S. Sheridan, Kevin M. McBride, Benjamin E. Gewurz, Heather D. Hickman, J. Craig Forrest, Laurie T. Krug
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription factor signal transducer and activator of transcription 3 (STAT3)
Externí odkaz:
https://doaj.org/article/6bccdfd5801d4610bd4ecd1dd2dfb2cc
Autor:
Luxin Pei, Heather D. Hickman
Publikováno v:
Viruses, Vol 16, Iss 5, p 679 (2024)
The skin is a complex tissue that provides a strong physical barrier against invading pathogens. Despite this, many viruses can access the skin and successfully replicate in either the epidermal keratinocytes or dermal immune cells. In this review, w
Externí odkaz:
https://doaj.org/article/23dae0dc0d6343d9bd898fd2256fedfa
Autor:
Ramon A. Lujan, Luxin Pei, John P. Shannon, Nathânia Dábilla, Patrick T. Dolan, Heather D. Hickman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
After recognition of cognate antigen (Ag), effector CD8+ T cells secrete serine proteases called granzymes in conjunction with perforin, allowing granzymes to enter and kill target cells. While the roles for some granzymes during antiviral immune res
Externí odkaz:
https://doaj.org/article/7c0fe53a5ce04007a06470d8bca5d607
Autor:
Alexandra M. Ortiz, Jennifer Simpson, Charlotte A. Langner, Phillip J. Baker, Cynthia Aguilar, Kelsie Brooks, Jacob K. Flynn, Carol L. Vinton, Andrew R. Rahmberg, Heather D. Hickman, Jason M. Brenchley
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Defective gastrointestinal barrier function and, in turn, microbial translocation have been identified as significant contributors to persistent inflammation in antiretroviral (ARV)-treated people living with HIV. Metabolic supplementation o
Externí odkaz:
https://doaj.org/article/cf5b60b70f2f47a591ba68af57beaeed
Autor:
Glennys V. Reynoso, David N. Gordon, Anurag Kalia, Cynthia C. Aguilar, Courtney S. Malo, Maya Aleshnick, Kimberly A. Dowd, Christian R. Cherry, John P. Shannon, Sophia M. Vrba, Autumn C. Holmes, Yael Alippe, Sonia Maciejewski, Kenichi Asano, Michael S. Diamond, Theodore C. Pierson, Heather D. Hickman
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112126- (2023)
Summary: To disseminate through the body, Zika virus (ZIKV) is thought to exploit the mobility of myeloid cells, in particular monocytes and dendritic cells. However, the timing and mechanisms underlying shuttling of the virus by immune cells remains
Externí odkaz:
https://doaj.org/article/1e565ee0ec8c4a429c99464dca821ac4
Autor:
Elise M. Peauroi, Stephen D. Carro, Luxin Pei, Glennys V. Reynoso, Heather D. Hickman, Laurence C. Eisenlohr
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105510- (2022)
Summary: The success of poxviruses as pathogens depends on their antagonism of host responses by multiple immunomodulatory proteins. The largest of these expressed by ectromelia virus (the agent of mousepox) is C15, one member of a well-conserved pox
Externí odkaz:
https://doaj.org/article/41539fa9dc7747d48d5dfae0593e5e35