Zobrazeno 1 - 10
of 34
pro vyhledávání: '"D Henriksen-Destefano"'
Publikováno v:
The Journal of Immunology. 135:1851-1856
Interferon (IFN)-gamma production, stimulated by the addition of exogenous interleukin (IL) 2, T cell mitogens, or tuberculin purified protein derivative (PPD) was studied in cultures of separated human mononuclear cells or unseparated peripheral blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74949f636c717ae7d6b98c43b507401
https://doi.org/10.4049/jimmunol.135.3.1851
https://doi.org/10.4049/jimmunol.135.3.1851
Autor:
Berish Y. Rubin, Bharat B. Aggarwal, E Rinderknecht, Junming Le, Donna S. Stone-Wolff, D. Henriksen-Destefano, Y K Yip, Jan Vilcek, H C Kelker
Publikováno v:
The Journal of Experimental Medicine
Crude preparations of interferon (IFN)-gamma derived from human peripheral blood leukocyte (PBL) cultures induced with 12-O-tetra-decanoylphorbol-13-acetate (TPA) and phytohemagglutinin (PHA) were more cytotoxic to HeLa cells than partially purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ade935039031d8558fac7c47671d807
https://doi.org/10.1084/jem.159.3.828
https://doi.org/10.1084/jem.159.3.828
Publikováno v:
The Journal of Immunology. 136:4525-4530
Bacterial lipopolysaccharide (LPS) induced human peripheral blood mononuclear cells (PBMC) to produce interferon-gamma (IFN-gamma). Monocytes play a mandatory accessory role in this process, because purified T lymphocytes failed to produce IFN-gamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19f9a02901c582474a9e41632e2a63e8
https://doi.org/10.4049/jimmunol.136.12.4525
https://doi.org/10.4049/jimmunol.136.12.4525
Autor:
D. Henriksen-Destefano, M Hirai, Rena Feinman, Jan Vilcek, C Swenson, Vito J. Palombella, Masafumi Tsujimoto
Publikováno v:
The Journal of Experimental Medicine
Tumor necrosis factor (TNF) is a monocyte-derived protein cytotoxic or cytostatic for some tumor cell lines. Here we show that highly purified E. coli-derived recombinant human TNF stimulated the growth of human FS-4 diploid fibroblasts. Stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb60e3a186956040a7c3df962302e6fd
http://europepmc.org/articles/PMC2188056
http://europepmc.org/articles/PMC2188056
Autor:
Bharat B. Aggarwal, H C Kelker, D. Henriksen-Destefano, Joel D. Oppenheim, Donna S. Stone-Wolff, Henry C. Stevenson, Jan Vilcek
Publikováno v:
International Journal of Cancer. 36:69-73
Cultures of human peripheral blood leukocytes (PBL) induced with phytohemagglutinin (PHA) and the phorbol ester 12-0-tetradecanoylphorbol 13-acetate (TPA) produced two types of cytotoxic proteins, indistinguishable in the in vitro assay employing mur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26633a332c7417ebe3ed12cbcf07fdd7
https://doi.org/10.1002/ijc.2910360112
https://doi.org/10.1002/ijc.2910360112
Publikováno v:
The Journal of Immunology. 138:635-640
The mechanism of human peripheral blood monocyte-mediated cytotoxicity for tumor cells was investigated, using the A673 human rhabdomyosarcoma and HT-29 human colon adenocarcinoma lines as target cells. A673 cells were shown to be susceptible to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab3356f682170b857328d422793df186
https://doi.org/10.4049/jimmunol.138.2.635
https://doi.org/10.4049/jimmunol.138.2.635
Publikováno v:
Journal of cellular physiology. 132(2)
Tumor necrosis factor (TNF), interleukin-1 (IL-1), and epidermal growth factor (EGF) were mitogenic for human diploid FS-4 fibroblasts. Dexamethasone amplified the growth-stimulating action of all three agents. Amplification of the growth-stimulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3437ccbd58983bac237ee3a990747a
https://pubmed.ncbi.nlm.nih.gov/3040777
https://pubmed.ncbi.nlm.nih.gov/3040777
Publikováno v:
Journal of cellular physiology. 130(1)
The synthetic double-stranded RNA polyinosinate-polycytidylate (poly(l).poly(C)) was mitogenic in cultures of human foreskin fibroblasts, as demonstrated by a stimulation of /sup 3/H-thymidine incorporation and an increase in cell density. Poly(l).po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad2967d2b055666bc882a6fd84487a2
https://pubmed.ncbi.nlm.nih.gov/3805129
https://pubmed.ncbi.nlm.nih.gov/3805129
Autor:
Amy D. Klion, D. Henriksen-Destefano, Morton Davidson, Alex Zemtsov, David M. Davidson, Jan Vilcek, Junming Le, Alvin E. Friedman-Kien
Publikováno v:
Journal of clinical immunology. 6(2)
Production of interferon (IFN)-gamma by peripheral blood leukocytes (PBL) was examined in cultures of unseparated fresh whole blood exposed to phytohemagglutinin (PHA), concanavalin A (Con A), or pokeweed mitogen (PWM). The yield of IFN-gamma was mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e0646ba504199f11356b04354a8aea
https://pubmed.ncbi.nlm.nih.gov/3086365
https://pubmed.ncbi.nlm.nih.gov/3086365
Publikováno v:
Cell. 45(5)
Earlier studies showed that tumor necrosis factor (TNF) exerts a mitogenic effect in human diploid fibroblasts. Here we demonstrate that purified E. coli-derived recombinant human TNF inhibits encephalomyocarditis virus replication in "aged" human fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3c637be0c538479bccd2947a7e56e9
https://pubmed.ncbi.nlm.nih.gov/2871942
https://pubmed.ncbi.nlm.nih.gov/2871942