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Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus

Autor: Richard S. Howk, D H Troxler, Douglas R. Lowy, Howard A. Young, Edward M. Scolnick

Publikováno v: Proceedings of the National Academy of Sciences. 74:4671-4675

The spleen focus-forming virus (SFFV), a replication-defective murine leukemia virus that causes the rapid transformation of certain hematopoietic target cells, has acquired specific xenotropic viral genetic information not contained in Friend helper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80618e4057df0e09fb2eb9e99e278d6b
https://doi.org/10.1073/pnas.74.10.4671

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Three laboratory strains of spleen focus-forming virus: comparison of their genomes and translational products

Autor: Edward M. Scolnick, Sandra K. Ruscetti, D H Troxler, David L. Linemeyer

Publikováno v: Journal of Virology. 33:140-151

The molecular properties of three laboratory strains of the spleen focus-forming virus were compared. All strains contain genetic sequences related to the env gene of mink cell focus-inducing murine type C leukemia viruses, and each strain codes for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f886bdcb4d7049df31dc83abf1f56c2b
https://doi.org/10.1128/jvi.33.1.140-151.1980

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Type-specific radioimmunoassays for the gp70s of mink cell focus-inducing murine leukemia viruses: expression of a cross-reacting antigen in cells infected with the friend strain of the spleen focus-forming virus

Autor: David L. Linemeyer, John Feild, Edward M. Scolnick, Sandra K. Ruscetti, D H Troxler

Publikováno v: The Journal of Experimental Medicine

We have isolated the gp70 of a helper-independent strain of a Friend mink cell focus-inducing (MCF) virus, Fr-MCF-1. This recombinant virus, like the previously described AKR-MCF viruses, has been shown by both biological and biochemical means to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b155ef9c59687aa614ec33e82be6f02
http://europepmc.org/articles/PMC2184990

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RNAs of Defective and Nondefective Components of Friend Anemia and Polycythemia Virus Strains Identified and Compared

Autor: Leonard Evans, Michael Nunn, Edward M. Scolnick, Peter H. Duesberg, D H Troxler

Publikováno v: Cold Spring Harbor Symposia on Quantitative Biology. 44:823-835

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e656d1eef8158e86232a01126dbcc0d
https://doi.org/10.1101/sqb.1980.044.01.087

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Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: potential relationship to the origin of replication- defective spleen focus-forming virus

Autor: Sandra K. Ruscetti, D H Troxler, David L. Linemeyer, E Yuan, Edward M. Scolnick

Publikováno v: The Journal of Experimental Medicine

Recent studies have indicated that both the replication-defective spleen focus-forming virus (SFFV) in the Friend virus complex and the helper-independent mink cell focus-inducing (MCF) viruses derived from AKR-murine leukemia virus (MuLV) are env ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9ce9f332a4805a0e22264fd36fca95
http://europepmc.org/articles/PMC2184996

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Helper-independent and replication-defective erythroblastosis-inducing viruses contained within anemia-inducing Friend virus complex (FV-A)

Autor: Edward M. Scolnick, David L. Linemeyer, Sandra K. Ruscetti, D H Troxler

Publikováno v: Virology. 102(1)

Helper-independent and replication-defective viruses contained within the anemia-inducing Friend virus complex have been analyzed. Helper-independent ecotropic viruses, F-MuLV, have been isolated which produce rapid hepatosplenomegaly and anemia when

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3778ee523e2f65705e07a9d30693d148
https://pubmed.ncbi.nlm.nih.gov/6929139

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Mapping host range-specific oligonucleotides within genomes of the ecotropic and mink cell focus-inducing strains of Moloney murine leukemia virus

Autor: Thomas Y. Shih, M O Weeks, John M. Coffin, Edward M. Scolnick, D H Troxler

The site of recombination of a mink cell focus-inducing strain (Mo-MuLV83) derived from an ecotropic Moloney murine leukemia virus (Mo-MuLV) was mapped by fingerprint analysis of the large RNase T1-resistant oligonucleotides, employing a two-dimensio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfabe8a1b51534f4823b05043ea4377
https://europepmc.org/articles/PMC354035/

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The spleen focus-forming virus (SFFV)-specific neoantigen shares cross-reactive determinants with mink cell focus-inducing (MCF) virus gp70

Autor: S, Gillis, S K, Ruscetti, A E, Gillis, D H, Troxler, E M, Scolnick, K A, Smith

Publikováno v: Virology. 96(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49a73033903c2eb9369d51cdf2fac591
https://pubmed.ncbi.nlm.nih.gov/88803

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Isolation of a fibroblast nonproducer cell line containing the Friend strain of the spleen focus-forming virus

Autor: D H Troxler, William C. Vass, Wade P. Parks, Edward M. Scolnick

Publikováno v: Virology. 76(2)

A BALB/c spleen homogenate containing a mixture of B-tropic type-C helper virus and the Friend strain of spleen focus-forming virus (SFFV) was found by end point titration to contain equivalent biologic titers of helper virus and SFFV. By infection o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869f7d2bb49dce1fb29acdb618398153
https://pubmed.ncbi.nlm.nih.gov/190768

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