Výsledky vyhledávání - "D H R, Blackwood"

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

Autor: Volker Arolt, Maurizio Fava, Willem A. Nolen, Markus M. Nöthen, Alexandra Schosser, R. van Dyck, D. H. R. Blackwood, Katharina Domschke, K. Pirlo, S.D. Gordon, Michael R. James, N. G. Martin, Wolfgang Maier, Marcella Rietschel, A. C. Heath, Yi Hu, Martin A. Kohli, Grant W. Montgomery, Susanne Lucae, Jordan W. Smoller, August B. Smit, Bernhard T. Baune, Donald J. MacIntyre, Qianchuan He, Anne Farmer, Kevin A. McGhee, Jouke-Jan Hottenga, Frans G. Zitman, Peter McGuffin, B.W.J.H. Penninx, Florian Holsboer, Dorret I. Boomsma, Patrick F. Sullivan, Jan Smit, Danielle Posthuma, Witte J.G. Hoogendijk, Danyu Lin, T. Zandbelt, Naomi R. Wray, Matthijs Verhage, Gonneke Willemsen, Jung-Ying Tzeng, Peter Heutink, E.J.C. de Geus, Walter J. Muir, Patrizia Rizzu, Roy H. Perlis, Sven Cichon, William L. Coventry

Publikováno v: Sullivan, P F, de Geus, E J C, Willemsen, G, James, M R, Smit, J H, Zandbelt, T, Arolt, V, Baune, B T, Blackwood, D, Cichon, S, Coventry, W L, Domschke, K, Farmer, A, Fava, M, Gordon, S D, He, Q, Heath, A C, Heutink, P, Holsboer, F, Hoogendijk, W J G, Hottenga, J J, Hu, Y, Kohli, M, Lin, D, Lucae, S, MacIntyre, D J, Maier, W, McGhee, K A, McGuffin, P, Montgomery, GW, Muir, W J, Nolen, W A, Nöthen, M M, Perlis, R H, Pirlo, K, Posthuma, D, Rietschel, M, Rizzu, P, Schosser, A, Smit, A B, Smoller, J W, Tzeng, J Y, van Dyck, R, Verhage, M, Zitman, F G, Martin, N G, Wray, N R, Boomsma, D I & Penninx, B W J H 2009, ' Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo ', Molecular Psychiatry, vol. 14, no. 4, pp. 359-375 . https://doi.org/10.1038/mp.2008.125
Molecular Psychiatry, 14(4), 359-375. Nature Publishing Group
Molecular psychiatry
Sullivan, P F, de Geus, E J C, Willemsen, G, James, M R, Smit, J H, Zandbelt, T, Arolt, V, Baune, B T, Blackwood, D, Cichon, S, Coventry, W L, Domschke, K, Farmer, A, Fava, M, Gordon, S D, He, Q, Heath, A C, Heutink, P, Holsboer, F, Hoogendijk, W J, Hottenga, J J, Hu, Y, Kohli, M, Lin, D, Lucae, S, MacIntyre, D J, Maier, W, McGhee, K A, McGuffin, P, Montgomery, G W, Muir, W J, Nolen, W A, Noethen, M M, Perlis, R H, Pirlo, K, Posthuma, D, Rietschel, M, Rizzu, P, Schosser, A, Smit, A B, Smoller, J W, Tzeng, J-Y, van Dyck, R, Verhage, M, Zitman, F G, Martin, N G, Wray, N R, Boomsma, D I & Penninx, B W J H 2009, ' Genome-wide association for major depressive disorder : a possible role for the presynaptic protein piccolo ', Molecular Psychiatry, vol. 14, no. 4, pp. 359-375 . https://doi.org/10.1038/mp.2008.125

Major depressive disorder (MDD) is a common complex trait with enormous public health significance. As part of the Genetic Association Information Network initiative of the US Foundation for the National Institutes of Health, we conducted a genome-wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbca8f9344ca3e15fd997af48d489fc5
https://doi.org/10.1038/mp.2008.125

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The association between lower educational attainment and depression owing to shared genetic effects?: Results in ~25,000 subjects

Autor: Patricia A. Peyser, Jessica D. Faul, Patrik K. E. Magnusson, Nicholas D. Hastie, Beate St Pourcain, Marcus Ising, Gérard Waeber, Behrooz Z. Alizadeh, Judith M. Vonk, Lawrence F. Bielak, Sang Hong Lee, Wouter J. Peyrot, Thomas Illig, M. M. Weissman, Nicholas J. Timpson, George Dedoussis, Nicholas G. Martin, Tomi E. Mäkinen, Jorma Viikari, Lili Milani, Harold Snieder, Laura J. Bierut, A. C. Heath, Reinhold E. Schmidt, Mariza de Andrade, Vilmundur Gudnason, K. Petrovic, Robert M. Kirkpatrick, Marcela González Gross, William G. Iacono, Michelle N. Meyer, Henry Völzke, Marisa Loitfelder, Maria Dimitriou, Lude Franke, Robert F. Krueger, E. J. C. G. van den Oord, Sven Cichon, Michael Conlon O'Donovan, Ian W. Craig, Shawn N. Murphy, Danielle Posthuma, Brenda W.J.H. Penninx, Aarno Palotie, Roy Thurik, Panos Deloukas, Matt McGue, M. Preisig, Patricia A. Boyle, Osorio Meirelles, Ben A. Oostra, Klaus Berger, G. M. Montgomery, Sharon L.R. Kardia, Peter K. Joshi, K. Stefansson, Paul Lichtenstein, Andrew Heath, Andrea Schulz, Dena G. Hernandez, Debbie A Lawlor, S. P. Hamilton, James B. Potash, Z. Kutalik, Elisabeth Widen, Emil L. Sigurdsson, Rudolf S N Fehrmann, Matthias Nauck, Mikael Landén, Kurt Lohman, S.D. Gordon, Lefkos T. Middleton, Caroline Hayward, Anjali K. Henders, Philipp Koellinger, Jeffrey A. Boatman, G van Grootheest, M. Daly, Jian Yang, Peter Vollenweider, Penelope A. Lind, Stacy Steinberg, Frank J. A. van Rooij, Florian Holsboer, Hkon K. Gjessing, Erkki Vartiainen, Magnus Johannesson, Jingmei Li, David Laibson, Henrik Grönberg, Tõnu Esko, Ivana Kolcic, Niina Eklund, Kelly S. Benke, Henning Tiemeier, Isaac S. Kohane, Nicolas W. Martin, Ronny Myhre, Frans G. Zitman, Arpana Agrawal, James F. Wilson, Michael R. Barnes, Lei Yu, Thorgeir E. Thorgeirsson, Franois Bastardot, Katri Räikkönen, William Lawson, Willem A. Nolen, M. Rietschel, René Breuer, Bertram Müller-Myhsok, James A. Knowles, Grant W. Montgomery, Eva Reinmaa, Rudolf Uher, Andreas Mielck, Luigi Ferrucci, S. E. Medland, Yuri Milaneschi, Philip L. De Jager, Manfred Uhr, A. E. Farmer, Cornelia M. van Duijn, Samuli Ripatti, Marja-Liisa Nuotio, Manuel Mattheisen, Sebastian E. Baumeister, David R. Van Wagoner, Martin Preisig, Fernando Rivadeneira, Peter Lichtner, Christopher Oldmeadow, Hreinn Stefansson, Ian B. Hickie, Darina Czamara, Elizabeth G. Holliday, Astanand Jugessur, Carla A. Ibrahim-Verbaas, Jaime Derringer, Vivian S. Gainer, P. Muglia, Daniel J. Benjamin, Patrick K.E. Magnusson, Patience J. Gallagher, Jennifer A. Smith, Lynn Cherkas, Pamela A. F. Madden, David A. Bennett, Zoltán Kutalik, George Davey-Smith, Gudny Eiriksdottir, Jens Treutlein, N. Craddock, Juliette Harris, Antti Latvala, Roy H. Perlis, Markus M. Noethen, Jan-Emmanuel De Neve, Stanley I. Shyn, J.H. Smit, Dalton Conley, Adriaan Hofman, Jari Lahti, Patrick J. F. Groenen, Jüri Allik, Albert V. Smith, Ozren Polasek, Susan M. Ring, Thomas Bettecken, Michele L. Pergadia, Patrick J. McGrath, Katherine E. Tansey, Stephan Ripke, Hogni Oskarsson, Peng Lin, Douglas F. Levinson, Matthijs J. H. M. van der Loos, Melissa E. Garcia, Jonathan P. Beauchamp, Rodney J. Scott, Zhihong Zhu, Michel Guipponi, Lyle J. Palmer, Alexander Teumer, William Coryell, Stefan Kloiber, Gonneke Willemsen, John Frank, Victor M. Castro, Andrew M. McIntosh, John M. Starr, Antonio Terracciano, Mika Kähönen, Marco Masala, Markus Perola, André G. Uitterlinden, Sutapa Mukherjee, Alexander Viktorin, Lenore J. Launer, Elisabeth B. Binder, William A. Scheftner, Christel M. Middeldorp, D. H. R. Blackwood, I. Jones, Thais S. Rizzi, A. Teumer, Cornelius A. Rietveld, Aldo Rustichini, Guy Lewis, Susan L. Slager, David M. Evans, Dorret I. Boomsma, Harry Campbell, Susanne Churchill, Johan G. Eriksson, Alan F. Wright, Dan V. Iosifescu, W. Maier, Francesco Cucca, Federica Tozzi, David R. Weir, Eva Albrecht, L. Milani, Jennifer R. Harris, Min A. Jhun, Marjo-Riitta Järvelin, Martin F. Elderson, Ute Bültmann, Olli T. Raitakari, Konstantin Shakhbazov, Krista Fischer, Thomas G. Schulze, T. Jung-Ying, P. Lichtenstein, Terho Lethimäki, Jeffrey B. Weilburg, Rolf Holle, Bo Jacobsson, Pedro Marques Vidal, Jordan W. Smoller, Stavroula Kanoni, Kati Kristiansson, Sergey Goryachev, Michael Steffens, Peter M. Visscher, Toshiko Tanaka, Donald J. MacIntyre, Witte J.G. Hoogendijk, David Schlessinger, Ian J. Deary, Harm-Jan Westra, Erik Ingelsson, E.J.C. de Geus, Franziska Degenhardt, Lydia Quaye, John Barnard, David C. Liewald, John P. Rice, Christopher F. Chabris, P. McGuffin, Tamara B. Harris, C. M. Lewis, Gail Davies, Enda M. Byrne, H.-Erich Wichmann, Sara Hägg, David Cesarini, Najaf Amin, Juha Karjalainen, Dale R. Nyholt, Christian Gieger, Per Hall, Ania Korszun, Neale Bm, Wei Zhao, Abdel Abdellaoui, Andres Metspalu, Christina Holzapfel, Jae Hoon Sul, Christiaan de Leeuw, Antti-Pekka Sarin, Ida Surakka, Veikko Salomaa, Mina K. Chung, N. L. Pedersen, Gerome Breen, P. A. F. Madden, Martin A. Kohli, J Kaprio, John Attia, Jing Shi, Gibran Hemani, Rauli Svento, Veronique Vitart, Susanne Lucae, L. A. Jones, Jouke-Jan Hottenga, Daniel S. Evans, Hans-Jörgen Grabe, Yongmei Liu, Danyu Lin, Albert Hofman, George McMahon, Naomi R. Wray, Stefan Herms, Stefania Bandinelli, W. Hoffmann, P.F. Sullivan, Susanne Hoefels, Michael B. Miller, Alan W. McLean, Igor Rudan, Jürgen Wellmann, Anu Realo, Maurizio Fava, Matthew Kowgier, Marika Kaakinen, Helena Schmidt

Publikováno v: Molecular Psychiatry, 20(6), 735-43. Nature Publishing Group
Molecular Psychiatry
Molecular Psychiatry, 20(6), 735-743. Nature Publishing Group
Peyrot, W, Lee, S H, Milaneschi, Y, Abdellaoui, A, Byrne, E M, Esko, T, de Geus, E J C, Hemani, G, Hottenga, J J, Kloiber, S, Levinson, D F, Lucae, S, Martin, N G, Medland, S E, Metspalu, A, Milani, L, Noethen, M M, Potash, J B, Rietschel, M, Rietveld, C A, Ripke, S, Shi, J, Willemsen, G, Zhu, Z, Boomsma, D I, Wray, N R, Posthuma, D, Middeldorp, C M & Penninx, B W J H 2015, ' The association between lower educational attainment and depression owing to shared genetic effects? Results in ~ 25 000 subjects ', Molecular Psychiatry, vol. 20, no. 6, pp. 735-743 . https://doi.org/10.1038/mp.2015.50
Molecular psychiatry, vol. 20, no. 6, pp. 735-743
Mol. Psychiatry 20, 735-743 (2015)

An association between lower educational attainment (EA) and an increased risk for depression has been confirmed in various western countries. This study examines whether pleiotropic genetic effects contribute to this association. Therefore, data wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c0a1620fc07d50183075e23248a8b3
https://research.rug.nl/en/publications/cb783c39-769d-4d2e-b486-29467e6a85e5

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Genetics of Schizophrenia and Bipolar Affective Disorder: Strategies to Identify Candidate Genes

Autor: J. K. Millar, Kathryn L. Evans, Walter J. Muir, Benjamin S. Pickard, Rachel James, P. A. Thomson, Peter M. Visscher, Stuart MacGregor, D. H. R. Blackwood, Naomi R. Wray, David J. Porteous

Publikováno v: Cold Spring Harbor Symposia on Quantitative Biology. 68:383-394

Schizophrenia (SCZ) and bipolar affective disorder(BPAD) (formerly termed manic-depressive illness) aresevere, disabling psychiatric illnesses that feature prominently in the top ten causes of disability worldwide (Lopezand Murray 1998). Each will af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93970d370cfdc892196bc3124d30ac8d
https://doi.org/10.1101/sqb.2003.68.383

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Case–control study of neurocognitive function in euthymic patients with bipolar disorder: An association with mania

Autor: Walter J. Muir, Jonathan Cavanagh, M. Van Beck, D. H. R. Blackwood

Publikováno v: British Journal of Psychiatry. 180:320-326

BackgroundNeurocognitive impairments in euthymic patients with bipolar disorder may represent trait rather than state variables.AimsTo test the hypothesis that euthymic patients with bipolar disorder would exhibit impairment in verbal learning and me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0e930181166d27aa7781e3e212aa07e
https://doi.org/10.1192/bjp.180.4.320

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A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing

Autor: Brian Dougherty, Thomas A. Lanz, D. H. R. Blackwood, D. St Clair, Baohong Zhang, A Power, Stephanie Hall, R Kleiman, Wen He, Stephen M. Lawrie, Sara A. Paciga, Andrew M. McIntosh, XiaoSu Hu, Siby John, W Liu, Nicholas J. Brandon

Publikováno v: Hu, X, Zhang, B, Liu, W, Paciga, S, He, W, Lanz, T A, Kleiman, R, Dougherty, B, Hall, S K, McIntosh, A M, Lawrie, S M, Power, A, John, S L, Blackwood, D, St Clair, D & Brandon, N J 2014, ' A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing ', Molecular Psychiatry, vol. 19, no. 8, pp. 857-8 . https://doi.org/10.1038/mp.2013.131
Molecular Psychiatry

The genetic architecture of schizophrenia is likely contributed by both common and rare variants.1 Recent genome-wide studies have revealed that common variants in the major histocompatibility complex (MHC) region, TCF4 and other genes are associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39fb0d47d7648db0f9db4aae3298fca
https://hdl.handle.net/20.500.11820/74c59c9a-23fe-443d-8543-ece53dbabf00

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Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia

Autor: Sheila Christie, David J. Porteous, D Hsiao-Wei Loh, Benoit Arveiler, J K Millar, D. H. R. Blackwood, D. Lawson, Susan Anderson, Walter J. Muir, Rebecca S. Devon

Publikováno v: Molecular Psychiatry. 6:173-178

Two overlapping and antiparallel genes on chromosome 1, Disrupted In Schizophrenia 1 and 2 (DISC1 and DISC2), are disrupted by a (1;11)(q42.1;q14.3) translocation which segregates with schizophrenia through at least four generations of a large Scotti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bc79edb3102117e544b18f904e5409
https://doi.org/10.1038/sj.mp.4000784

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Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

Publikováno v: Molecular Psychiatry, 16(1), 2-4. Nature Publishing Group
Liu, Y, Blackwood, D H, Caesar, S, de Geus, E J C, Farmer, A, Ferreira, M A R, Ferrier, I N, Fraser, C, Gordon-Smith, K, Green, E K, Grozeva, D, Gurling, H M, Hamshere, M L, Heutink, P, Holmans, P A, Hoogendijk, W J G, Hottenga, J J, Jones, L, Jones, I R, Kirov, G, Lin, D, McGuffin, P, Moskvina, V, Nolen, W A, Perlis, R H, Posthuma, D, Scolnick, E M, Smit, A B, Smit, J H, Smoller, J W, St Clair, D, van Dyck, R, Verhage, M, Willemsen, G, Young, A H, Zandbelt, T, Boomsma, D I, Craddock, N, O’Donovan, M C, Owen, M J, Penninx, B W J H, Purcell, S, Sklar, P & Sullivan, P F 2011, ' Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder ', Molecular Psychiatry, vol. 16, no. 1, pp. 2-4 . https://doi.org/10.1038/mp.2009.107

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b235a6677ceffda056c42cc65423e3cf
https://doi.org/10.1038/mp.2009.107

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