Zobrazeno 1 - 10
of 29
pro vyhledávání: '"D H Kono"'
Using the BXD2 mice as a model of arthritis: silicosis and silica-induced arthritis in the BXD2 mice
Publikováno v:
06.02 - Occupational and environmental health.
Publikováno v:
Seminars in Arthritis and Rheumatism. 29:385-399
In the past few years there has been an explosion of information in the area of NZ mouse research. This has reflected a general increase in knowledge and technology in cellular immunology and lymphocyte biology. Continuing research in many specific a
Publikováno v:
The Journal of Immunology. 155:3308-3312
Recent studies have documented incomplete TCR V alpha-chain allelic exclusion and dual V alpha-bearing T cells. Herein, we show that V beta allelic exclusion is also incomplete, since a significant proportion of peripheral T cells express dual V beta
Publikováno v:
The Journal of Immunology. 153:637-646
To further define the origin, selection, and diversity of hepatic T cells, we have determined V beta gene expression profiles in double negative (DN, CD4-8-) and single positive (SP, CD4+8- or CD8+4-) alpha beta + liver T cells of DBA/2 mice. These I
Publikováno v:
The Journal of Immunology. 152:2596-2600
Ten Lewis rat T cell lines responsive to Torpedo californica acetylcholine receptor (AChR) were assayed for TCR V beta usage. All lines were CD4+, OX-22-, and exhibited reactivity to one or more AChR chains. Several different V beta s were expressed
Publikováno v:
The Journal of Immunology. 147:4360-4365
To extend the characterization of the human V beta gene repertoire, we utilized anchored or V beta-specific polymerase chain reaction to generate a large (approximately 200 clones) beta-chain library from the thymus of a single individual. Nine new V
Publikováno v:
The Journal of Immunology. 146:879-883
Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system mediated by T cells bearing TCR of restricted heterogeneity. Thus, in the murine PL strain, V beta-8.2 is used by 80% of the encephalitogenic T cells
Autor:
D H, Kono, A N, Theofilopoulos
Publikováno v:
Current directions in autoimmunity. 1
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(1)
Imbalances of Th1- and Th2-type responses have been postulated to be a predisposing factor for both humoral and cellular mediated autoimmune diseases. To further define their roles in systemic autoimmunity, IL-4 and IFN-gamma gene knockout mice were
Background genes determine the incidence and severity of lymphoaccumulation and histopathologic manifestations of systemic autoimmunity in mice homozygous for the apoptosis-defective Faslpr mutation. By interval mapping of 274 F2 mice intercrossed be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1769b29a79c01e8dadddcf0fa7e505a
https://europepmc.org/articles/PMC508615/
https://europepmc.org/articles/PMC508615/