Zobrazeno 1 - 10
of 88
pro vyhledávání: '"D H Conrad"'
Publikováno v:
The Journal of Immunology. 154:4240-4246
The low-affinity receptor for IgE (Fc epsilon RII/CD23) is a type II integral membrane protein with an extracellular C-terminal sequence homologous to C-type animal lectins. Between this region and the membrane is a repetitive sequence predicted to f
Publikováno v:
The Journal of Immunology. 152:4388-4396
Targeting Ag to the Fc epsilon RII by Ag-specific IgE has been shown to be an efficient means of enhancing Ag presentation by B cells to Ag-specific T cells. To take advantage of the Fc epsilon RII as a targeting molecule and to investigate whether I
Autor:
J A, Mathews, J, Ford, S, Norton, D, Kang, A, Dellinger, D R, Gibb, A Q, Ford, H, Massay, C L, Kepley, P, Scherle, A D, Keegan, D H, Conrad
Publikováno v:
Allergy. 66(9)
Elevated levels of CD23, a natural regulator of IgE production, have been shown to decrease the signs of lung inflammation in mice. The aim of this study was to study the involvement of ADAM10, the primary CD23 sheddase, in experimental asthma.ADAM10
Publikováno v:
The Journal of Immunology. 150:2372-2382
The low affinity receptor for IgE (Fc epsilon RII/CD23) is a type II integral membrane protein with an extracellular C-terminal region homologous to C-type animal lectins. Immediately adjacent to this lectin homology region is a sequence that is pred
Publikováno v:
The Journal of Immunology. 150:31-38
Ag-bearing follicular dendritic cells (FDC) are found throughout secondary lymphoid tissues in close association with rapidly proliferating germinal center B lymphocytes. We reasoned that FDC might provide costimulatory signals that would enhance the
Publikováno v:
The Journal of Immunology. 148:2340-2347
The present study was undertaken to determine whether mouse follicular dendritic cells (FDC) bear Fc epsilon RII (CD23) and whether IgE-immune complexes are retained by FDC. Mouse Fc epsilon RII was localized by both L and electron microscopy using t
Publikováno v:
The Journal of Immunology. 146:211-216
Mast cell-committed progenitors are detected in the unique microenvironment of the mesenteric lymph node (MLN) of Nippostrongylus brasiliensis-infected mice but not in naive bone marrow. We have determined that MLN cells, after infection, produce hig
Publikováno v:
The Journal of Immunology. 145:2644-2651
PG of the E series are generally known to suppress immune responses, however, we have found that PGE synergizes with IL-4 to induce IgE and IgG1 production in LPS-stimulated murine B lymphocytes. PGE2 and PGE1 (10(-6) to 10(-8) M) significantly incre
Publikováno v:
Annals of the New York Academy of Sciences. 917
Androstenetriol (AET) and Androstenediol (AED) upregulate host immunity, leading to increased resistance against infections. AET augments IL-2, IL-3, IFN gamma levels, and counteracts hydrocortisone immune suppression. AET and AED at a dose of 0.75 m