Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D H, Presky"'
Autor:
Marc Feldmann, D H Presky, Debra M. Butler, Anne-Marie Malfait, Fionula M. Brennan, Ravinder Nath Maini
SUMMARYThe effect of blocking IL-12, a potent inducer of interferon-gamma (IFN-γ) and promoter of Th1 cell responses, during the induction phase of CIA was investigated. Arthritis was elicited in male DBA/1 mice by immunizing with type II collagen (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2fb33a45d26f36346921fca0571bdf
https://doi.org/10.1046/j.1365-2249.1998.00485.x
https://doi.org/10.1046/j.1365-2249.1998.00485.x
Publikováno v:
The Journal of Immunology. 155:4286-4294
Using DNA cross-hybridization, we have isolated and characterized cDNA clones encoding a mouse (mo) IL-12R beta component. Two forms of cDNA were found. The first form encodes a receptor protein that has an overall structure very similar to that of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::579c830a74d4a9635240d8285209481e
https://doi.org/10.4049/jimmunol.155.9.4286
https://doi.org/10.4049/jimmunol.155.9.4286
Autor:
A O Chua, R Chizzonite, B B Desai, T P Truitt, P Nunes, L J Minetti, R R Warrier, D H Presky, J F Levine, M K Gately
Publikováno v:
The Journal of Immunology. 153:128-136
A cDNA encoding a human IL-12R subunit was isolated by expression cloning. This subunit is a 662 amino acid type I transmembrane protein with an extracellular domain of 516 amino acids and a cytoplasmic domain of 91 amino acids. It is a member of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d03e408e5351f804c7cc3427144dabd2
https://doi.org/10.4049/jimmunol.153.1.128
https://doi.org/10.4049/jimmunol.153.1.128
Publikováno v:
The Journal of Immunology. 148:2181-2185
It has recently been demonstrated that the gamma-subunits of the high affinity Fc epsilon RI are required for the cell surface expression of not only the Fc epsilon RI alpha-subunit, but also for the low affinity Fc gamma RIIIA alpha (CD16). In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81fcac20796e605cb1d5209e49b72fe6
https://doi.org/10.4049/jimmunol.148.7.2181
https://doi.org/10.4049/jimmunol.148.7.2181
Publikováno v:
The Journal of Immunology. 147:4263-4270
The TCR complex is composed of a clonotypic heterodimer (Ti alpha:beta or gamma:delta) noncovalently associated with the CD3 complex (gamma, delta, and epsilon), and with one or more disulfide-linked dimers whose components are designated zeta and et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb113abcf1c97256628f19103bd79378
https://doi.org/10.4049/jimmunol.147.12.4263
https://doi.org/10.4049/jimmunol.147.12.4263
Publikováno v:
The Journal of Immunology. 144:860-868
A novel class of cell surface proteins are attached to the plasma membrane via a phosphatidylinositol (PI)-glycan anchoring structure, and these proteins can be selectively removed from the cell surface by the enzyme PI-specific phospholipase C (PI-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f8d72fbc7856348ff08338a0162e10
https://doi.org/10.4049/jimmunol.144.3.860
https://doi.org/10.4049/jimmunol.144.3.860
Publikováno v:
European journal of immunology. 29(6)
Interleukin-12 (IL-12) is a heterodimeric cytokine composed of two disulfide-bonded subunits, p35 and p40, which has important regulatory effects on T cells and natural killer (NK) cells. In contrast to heterodimeric IL-12, a homodimer of the p40 sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce66c275decdd73fb28a02f5ab72dd16
https://pubmed.ncbi.nlm.nih.gov/10382764
https://pubmed.ncbi.nlm.nih.gov/10382764
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(4)
To determine whether the Th1 response in tuberculosis correlated with IL-12R expression, we measured expression of the IL-12R beta 1 and IL-12R beta 2 subunits, as well as IL-12R beta 2 mRNA expression in tuberculosis patients and healthy tuberculin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4b2da265d9e5d1d6c4946d25b2481a7
https://pubmed.ncbi.nlm.nih.gov/9973527
https://pubmed.ncbi.nlm.nih.gov/9973527
Publikováno v:
Chemical immunology. 68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80f75bb0ea65c093bd9037ad5d196335
https://pubmed.ncbi.nlm.nih.gov/9329214
https://pubmed.ncbi.nlm.nih.gov/9329214
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(9)
Using DNA cross-hybridization, we have isolated and characterized cDNA clones encoding a mouse (mo) IL-12R beta component. Two forms of cDNA were found. The first form encodes a receptor protein that has an overall structure very similar to that of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d61fd6d619e244784bf1a24a8efb738
https://pubmed.ncbi.nlm.nih.gov/7594587
https://pubmed.ncbi.nlm.nih.gov/7594587