Zobrazeno 1 - 10
of 64
pro vyhledávání: '"D H, Lynch"'
Publikováno v:
Environmental Entomology. 37:575-585
Publikováno v:
Canadian Journal of Plant Pathology. 28:52-62
The search for replacements for synthetic fungicides has prompted the examination of a range of plant-based composts and extracts as alternative crop-protection agents. A study was established to compare the relative efficacy of the commercially avai
Publikováno v:
The Journal of Immunology. 163:1289-1297
Daily treatment of mice with fms-like tyrosine kinase 3 ligand (Flt3L) leads to a significant increase in the number of dendritic cells and induces antitumor immunity. Here, we show that Flt3L and CD40 ligand (CD40L) synergize in the generation of im
Publikováno v:
The Journal of Immunology. 159:1135-1139
Activation-induced cell death (AICD) is initiated by the TCR-dependent up-regulation of Fas ligand (FasL) mRNA. The subsequently generated soluble or cell-associated FasL gene products bind Fas, leading to apoptosis of the T cells. Although TCR stimu
Autor:
Yuki Kimura, Kyoko Inagaki-Ohara, D. H. Lynch, Yasunobu Yoshikai, Tetsu Sakai, Kazuo Kusugami
Publikováno v:
Gastroenterology. 113:168-174
BACKGROUND & AIMS: Host-derived intestinal intraepithelial lymphocytes (IELs) increase in number during acute graft-versus-host disease (GVHD) in mice. In the present study, we examined Fas-mediated cytotoxicity by host-derived IELs against Fas-expre
Publikováno v:
The Journal of Immunology. 157:5315-5323
Mice genetically deficient in IL-7R(alpha) are highly lymphopenic in the peripheral lymphoid organs. The functional competence of T cells that have developed in the absence of an IL-7R signal was investigated. Three important observations were made u
Autor:
L C Foote, T J Schneider, G M Fischer, J K Wang, B Rasmussen, K A Campbell, D H Lynch, S T Ju, A Marshak-Rothstein, T L Rothstein
Publikováno v:
The Journal of Immunology. 157:1878-1885
CD40 ligand-activated B cells are sensitive targets for CD4+ Th1 effector cells that kill in a Fas-dependent fashion. Susceptibility to apoptosis is counteracted by Ag receptor binding that produces a state of resistance to Fas engagement in otherwis
Publikováno v:
Immunology. 87:581-585
CD4+ T-lymphocyte apoptosis has been associated with human immunodeficiency virus (HIV)-1 infection in vitro, paralleling the expression of Fas (APO-1, CD95) on peripheral blood mononuclear cells from patients with HIV disease. However, the link betw
Autor:
Debashis Mitra, Melissa G. Steiner, D H Lynch, Lisa Staiano-Coico, Frederick P. Siegal, Jeffrey Laurence
Publikováno v:
Journal of Clinical Investigation. 97:672-680
Progressive loss of CD4+ T lymphocytes, accompanied by opportunistic infections characteristic of the acquired immune deficiency syndrome, ahs been reported in the absence of any known etiology. The pathogenesis of this syndrome, a subset of idiopath