Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D H, Crouch"'
Autor:
F. Fisher, D. H. Crouch, Colin R. Goding, Padma-Sheela Jayaraman, David A. F. Gillespie, Wayne M. Clark
Publikováno v:
Scopus-Elsevier
The Myc oncoprotein has been implicated in control of cell growth, division and differentiation. Although Myc contains a bHLH-LZ motif, it fails to bind DNA alone but can do so by forming heterodimers with an unrelated bHLH-LZ protein, Max. Max homod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6204100fb300d444789ca7fd5b13d26a
https://ora.ox.ac.uk/objects/uuid:715467c9-f585-4796-aa57-d220372bdb33
https://ora.ox.ac.uk/objects/uuid:715467c9-f585-4796-aa57-d220372bdb33
Publikováno v:
Nucleic Acids Research
Interaction with Max via the helix-loop-helix/leucine zipper (HLH-LZ) domain is essential for Myc to function as a transcription factor. Myc is commonly upregulated in tumours, however, its activity can also be potentiated by virally derived mutation
Publikováno v:
Frame, M C, Simpson, K, Fincham, V J & Crouch, D H 1994, ' Separation of v-Src-induced mitogenesis and morphological transformation by inhibition of AP-1 ', Molecular Biology of the Cell, vol. 5, no. 11, pp. 1177-84 . < http://www.ncbi.nlm.nih.gov/pmc/articles/PMC301144/ >
v-Src activity results in both morphological transformation and reentry of quiescent chick embryo fibroblasts (CEF) into cell cycle. We have previously used temperature-sensitive v-Src mutants to show that enhanced activity of cellular AP-1 in the fi
Publikováno v:
The Journal of Cell Biology
To study the effects of myc oncogene on muscle differentiation, we infected the murine skeletal muscle cell line C2C12 with retroviral vectors encoding various forms of avian c- or v-myc oncogene. myc expression induced cell transformation but, unlik
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(10)
Transforming growth factor beta 1 (TGF-beta 1) is a potent inhibitor of keratinocyte proliferation and a potential tumor suppressor of squamous cell carcinomas (SCCs). TGF-beta 1 exerts its antiproliferative effects by inhibiting key transitions requ
Publikováno v:
Oncogene. 12(12)
The product of the c-myc proto-oncogene has a central role in induction of apoptosis, a physiological form of cell death characterised in vitro by morphological rounding, detachment and nuclear disintegration. Induction of apoptosis by serum withdraw
Autor:
S C, Barnett, D H, Crouch
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(1)
Oncogenes represent altered versions of cellular genes instrumental for control of cell proliferation and differentiation. Several oncogenes have been implicated in glial cell transformation and immortalization in culture (myc, src, mos, ras, and SV4
Publikováno v:
Microbiology. 128:2739-2746
SUMMARY: The ribosomal RNAs were isolated from cyanobacteria (Anacystis nidulans, Anabaena cylindrica, Anabaena CA and Nostoc MAC) and labelled in vitro with [γ-32P]ATP and polynucleotide kinase. DNA from the corresponding species was isolated, dige
Publikováno v:
Journal of Bacteriology. 156:979-982
Polyadenylated RNA was detected in the cyanobacteria Nostoc sp. strain MAC and Anabaena variabilis by oligodeoxythymidylic acid-cellulose chromatography and by hybridization to [3H]polyuridylic acid. Polyadenylate tracts from A. variabilis were locat