Zobrazeno 1 - 10
of 17
pro vyhledávání: '"D G de Freitas"'
Autor:
Philip F. Halloran, Chatchai Kreepala, J. Chang, Konrad S. Famulski, Jeff Reeve, D. G. de Freitas
Publikováno v:
American Journal of Transplantation. 13:634-644
We previously reported that kidney transplants with early acute injury express transcripts indicating injury repair—the acute kidney injury signal. This study investigated the significance of this signal in transplants with other conditions, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fb98739e6c034cee8f7650c27f7c3ae
https://doi.org/10.1111/ajt.12080
https://doi.org/10.1111/ajt.12080
Autor:
Jeff Reeve, A. Skene, D. G. de Freitas, Banu Sis, Joana Sellarés, Michael Mengel, Philip F. Halloran, Luis G. Hidalgo, Konrad S. Famulski
Publikováno v:
American Journal of Transplantation. 13:645-655
Histologic diagnosis of T cell-mediated rejection is flawed by subjective assessments, nonspecific lesions and arbitrary rules. This study developed a molecular test for T cell-mediated rejection. We used microarray results from 403 kidney transplant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5271e1a3c7413cdbb19711c569c1288b
https://doi.org/10.1111/ajt.12079
https://doi.org/10.1111/ajt.12079
Autor:
Jeff Reeve, D. G. de Freitas, Michael Mengel, Arthur J. Matas, Joana Sellarés, Philip F. Halloran, Luis G. Hidalgo, Gunilla Einecke, Konrad S. Famulski, Banu Sis
Publikováno v:
American Journal of Transplantation. 12:388-399
We prospectively studied kidney transplants that progressed to failure after a biopsy for clinical indications, aiming to assign a cause to every failure. We followed 315 allograft recipients who underwent indication biopsies at 6 days to 32 years po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3186ff48786d6cdac8e145abde73a421
https://doi.org/10.1111/j.1600-6143.2011.03840.x
https://doi.org/10.1111/j.1600-6143.2011.03840.x
Autor:
Gunilla Einecke, D. Kayser, D. G. de Freitas, Anke Schwarz, Michael Mengel, Wilfried Gwinner, J. Chang, Banu Sis, Konrad S. Famulski, L. Guembes-Hidalgo, H. Haller, Philip F. Halloran, V. Broecker
Publikováno v:
American Journal of Transplantation. 11:708-718
We assessed the molecular phenotype of 107 6-week protocol biopsies from human renal allografts, using Affymetrix microarrays. Transcript changes were summarized as nonoverlapping pathogenesis-based transcript sets (PBTs) reflecting inflammation (T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad3aaed23df57dda41b17dcbdac1e60
https://doi.org/10.1111/j.1600-6143.2010.03339.x
https://doi.org/10.1111/j.1600-6143.2010.03339.x
Autor:
Arthur J. Matas, Banu Sis, Joana Sellarés, Bruce Kaplan, Philip F. Halloran, Luis G. Hidalgo, D. G. de Freitas, Michael Mengel
Publikováno v:
American Journal of Transplantation. 11:489-499
Assessment of kidney transplant biopsies relies on nonspecific inflammatory lesions: Interstitial infiltrates (i), tubulitis (t) and intimal arteritis (v). We studied the relationship between inflammation and prognosis in biopsies for clinical indica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b608b52b01f4774731969c19aec35f4
https://doi.org/10.1111/j.1600-6143.2010.03415.x
https://doi.org/10.1111/j.1600-6143.2010.03415.x
Autor:
Philip F. Halloran, Jeff Reeve, M. Picton, Arthur J. Matas, D. G. de Freitas, Daniel Serón, Gunilla Einecke, Alexandre Pereira, Jonathan S. Bromberg, J. Chang, Joana Sellarés
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13(11)
In a reference set of 403 kidney transplant biopsies, we recently developed a microarray-based test that diagnoses antibody-mediated rejection (ABMR) by assigning an ABMR score. To validate the ABMR score and assess its potential impact on practice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53008c23779e7225f2784aff39698742
https://pubmed.ncbi.nlm.nih.gov/24119109
https://pubmed.ncbi.nlm.nih.gov/24119109
Autor:
Daniel Serón, Gunilla Einecke, Jonathan S. Bromberg, Arthur J. Matas, J. Chang, M. Picton, Alexandre Pereira, Joana Sellarés, Philip F. Halloran, Jeff Reeve, D. G. de Freitas
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13(9)
We previously developed a microarray-based test for T cell-mediated rejection (TCMR) in a reference set of 403 biopsies. To determine the potential impact of this test in clinical practice, we undertook INTERCOM, a prospective international study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dfbc74b07cd0de7d31a265cae45662
https://pubmed.ncbi.nlm.nih.gov/23915426
https://pubmed.ncbi.nlm.nih.gov/23915426
Autor:
D. G. de Freitas, Alison Skene, Konrad S. Famulski, Joana Sellarés, Michael Mengel, Chatchai Kreepala, Banu Sis, Alexandre Loupy, Philip F. Halloran, Luis G. Hidalgo, Jeff Reeve
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13(4)
Antibody-mediated rejection is the major cause of kidney transplant failure, but the histology-based diagnostic system misses most cases due to its requirement for C4d positivity. We hypothesized that gene expression data could be used to test biopsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a6f0d86222901baf390ddde3d95f1e
https://pubmed.ncbi.nlm.nih.gov/23414212
https://pubmed.ncbi.nlm.nih.gov/23414212
A new diagnostic algorithm for antibody-mediated microcirculation inflammation in kidney transplants
Autor:
Michael Mengel, Banu Sis, Gian S. Jhangri, Arthur J. Matas, D. G. de Freitas, J. Chang, Philip F. Halloran, Luis G. Hidalgo, J. Riopel
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12(5)
We studied the significance of microcirculation inflammation in kidney transplants, including 329 indication biopsies from 251 renal allograft recipients, who were mostly nonpresensitized (crossmatch negative). Glomerulitis (g) and peritubular capill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061ec461844234d3ee3b98d9b4a3d0c5
https://pubmed.ncbi.nlm.nih.gov/23141235
https://pubmed.ncbi.nlm.nih.gov/23141235
Autor:
Gunilla Einecke, Konrad S. Famulski, D. G. de Freitas, Michael Mengel, J. Chang, Joana Sellarés, Banu Sis, Philip F. Halloran, Luis G. Hidalgo
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12(1)
In kidney transplantation, many inflamed biopsies with changes insufficient to be called T-cell-mediated rejection (TCMR) are labeled "borderline", leaving management uncertain. This study examined the nature of borderline biopsies as a step toward e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36b58e5271721c3f4271eca846e665c
https://pubmed.ncbi.nlm.nih.gov/21992442
https://pubmed.ncbi.nlm.nih.gov/21992442