Zobrazeno 1 - 10
of 54
pro vyhledávání: '"D G Remick"'
Autor:
J K Brieland, L A Heath, G B Huffnagle, D G Remick, M S McClain, M C Hurley, R K Kunkel, J C Fantone, C Engleberg
Publikováno v:
The Journal of Immunology. 157:5002-5008
The potential role of humoral immunity in regulating intrapulmonary growth of Legionella pneumophila in the immunocompetent host was investigated using a murine model of Legionnaires' disease. Intratracheal inoculation of A/J mice with a virulent str
Publikováno v:
The Journal of Immunology. 148:2724-2730
Cytokines have been studied intensively to delineate their role in the altered pathophysiology observed in septic shock. We studied the role of TNF in the lethality of two well characterized models of septic shock by inhibiting TNF's activity with a
Publikováno v:
The Journal of Immunology. 148:2133-2141
TNF, IL-1, and IL-6 are integral components of the cytokine cascade released in the response to inflammatory stimuli such as LPS. IL-8 is produced both in response to LPS as well as TNF and IL-1. The early, local production of TNF and IL-1 may theref
Publikováno v:
The Journal of Immunology. 146:1437-1445
A human umbilical vein endothelial cell (EC)/monocyte (MC) coculture system was used to dissect cell:cell interactions associated with production of procoagulant activity (PCA) in response to two common stimuli of intravascular coagulation in vivo (L
Publikováno v:
The Journal of Immunology. 145:1430-1434
Accumulating evidence supports the hypothesis that neuroendocrine hormones may participate in immunologic processes. In our study we have determined that UK-14304 (UK) and norepinephrine (NE), both alpha 2-adrenergic agonists, can augment LPS-stimula
Publikováno v:
The Journal of Immunology. 144:3822-3828
We investigated, in vitro and in vivo, the cyclosporin A (CsA) regulation of LPS-induced TNF gene expression and subsequent pathophysiologic changes. In vitro dose-response kinetics data showed that CsA inhibited TNF bioactivity in the supernatant wi
Publikováno v:
British journal of pharmacology. 129(2)
1. We examined the effect of lipopolysaccharide (LPS), a cell wall constituent of Gram negative bacteria, on nuclear factor kappaB (NF-kappaB) activation in the intestine and the roles of endogenous platelet-activating factor (PAF), tumour necrosis f
Publikováno v:
Inflammation. 23(4)
C-X-C chemokines play an important role in the migration and activation of neutrophils (PMNs) during an inflammatory event. We measured mRNA and protein expression of the murine C-X-C chemokines macrophage inflammatory protein-2 (MIP-2) and KC in the
Autor:
H A, Hennein, U, Kiziltepe, S, Barst, K A, Bocchieri, A, Hossain, D R, Call, D G, Remick, J P, Gold
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 117(3)
Cardiopulmonary bypass is associated with the production of both proinflammatory and anti-inflammatory cytokines, the balance of which leads to varying degrees of postoperative systemic inflammation. Arteriovenous modified ultrafiltration effectively
Publikováno v:
Inflammation. 21(5)
Using an in vitro system for stimulating human peripheral blood mononuclear cells (PBMC) with immobilized Ig, patterns of cytokine production as a function of different Ig classes and subclasses were elucidated. Wells were coated with IgA, IgG1, IgG2