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The intracellular IL-1 receptor antagonist alters IL-1-inducible gene expression without blocking exogenous signaling by IL-1 beta

Autor: J M Watson, A K Lofquist, C A Rinehart, J C Olsen, S S Makarov, D G Kaufman, J S Haskill

Publikováno v: The Journal of Immunology. 155:4467-4475

The epithelium-associated tissue distribution of the intracellular IL-1R antagonist (icIL-1Ra) suggests that it functions as a novel regulatory molecule for IL-1 in somatic tissues. We examined the role of the icIL-1Ra in IL-1 beta-induced responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad598ded134a65ee95dfa5a0a35fd97e
https://doi.org/10.4049/jimmunol.155.9.4467

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Endometrial stromal cells regulate gap-junction function in normal human endometrial epithelial cells but not in endometrial carcinoma cells

Autor: S R, Schlemmer, D G, Kaufman

Publikováno v: Molecular carcinogenesis. 28(2)

Gap junctions are transmembrane proteins comprised of six connexin subunits that facilitate direct solute transport between adjacent cells through gap junctions. Previous studies from other laboratories have documented a correlation between reduced g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a5bf7199a00b9f58472625227dbae3e
https://pubmed.ncbi.nlm.nih.gov/10900463

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Construction of a cosmid library of DNA replicated early in the S phase of normal human fibroblasts

Autor: B P, Brylawski, S M, Cohen, J L, Longmire, N A, Doggett, M, Cordeiro-Stone, D G, Kaufman

Publikováno v: Journal of cellular biochemistry. 78(3)

We constructed a subgenomic cosmid library of DNA replicated early in the S phase of normal human diploid fibroblasts. Cells were synchronized by release from confluence arrest and incubation in the presence of aphidicolin. Bromodeoxyuridine (BrdUrd)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb3aac3e4a20fe93441931408232d089
https://pubmed.ncbi.nlm.nih.gov/10861848

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On the relationship of matrix association and DNA replication

Autor: B P, Brylawski, S M, Cohen, M, Cordeiro-Stone, M J, Schell, D G, Kaufman

Publikováno v: Critical reviews in eukaryotic gene expression. 10(1)

The nuclear matrix is believed to contain sites of assembly of protein complexes that catalyze the initiation of DNA replication as well as DNA elongation. To explore this relationship, DNA replicated by human fibroblasts at the beginning of the S ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d0477de592e5c95fe9b94397f686071
https://pubmed.ncbi.nlm.nih.gov/10813397

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The intracellular IL-1 receptor antagonist alters IL-1-inducible gene expression without blocking exogenous signaling by IL-1 beta

Autor: J M, Watson, A K, Lofquist, C A, Rinehart, J C, Olsen, S S, Makarov, D G, Kaufman, J S, Haskill

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 155(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3b1ebff67144df92ece9e11c637bc51
https://pubmed.ncbi.nlm.nih.gov/7594609

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Phenobarbital modulates the type of cell death by rat hepatocytes during deprivation of serum in vitro

Autor: C, Chiao, Y, Zhang, D G, Kaufman, W K, Kaufmann

Publikováno v: Hepatology (Baltimore, Md.). 22(1)

An immortal line of chemically altered rat hepatocytes was used to study the effects of the liver tumor promoter, phenobarbital (PB), on hepatocyte growth and viability in vitro. When the serum concentration in medium was changed from 10% to 0.5%, ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4082a032c752a45201b716d7effd16a8
https://pubmed.ncbi.nlm.nih.gov/7601424

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Association of putative origins of replication with the nuclear matrix in normal human fibroblasts

Autor: B P, Brylawski, G J, Tsongalis, M, Cordeiro-Stone, W T, May, L D, Comeau, D G, Kaufman

Publikováno v: Cancer research. 53(17)

Several metabolic processes, such as DNA organization and replication, transcription, and RNA processing are closely associated with the nuclear matrix. Nuclear matrix attachment regions are nucleotide sequences holding DNA tightly complexed with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::17ebd7a97716fe676165bcae922ac0af
https://pubmed.ncbi.nlm.nih.gov/8358710

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Identification of human DNA in complex biological samples using the Alu polymerase chain reaction

Autor: G J, Tsongalis, W B, Coleman, G L, Esch, G J, Smith, D G, Kaufman

Publikováno v: Journal of forensic sciences. 38(4)

Alu-Polymerase chain reaction (PCR) was used to amplify human DNA from complex mixed sources of DNA. Amplification of human DNA sequences by Alu-PCR could be accomplished in samples containing low concentrations of template in the presence of excess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae96b90bd1184f3f5a1fd9fdf1dc6b5d
https://pubmed.ncbi.nlm.nih.gov/8355011

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Partial characterization of nuclear matrix attachment regions from human fibroblast DNA using Alu-polymerase chain reaction

Autor: G J, Tsongalis, W B, Coleman, G J, Smith, D G, Kaufman

Publikováno v: Cancer research. 52(13)

The proteinaceous nuclear matrix of mammalian cell nuclei has been suggested to be involved in the regulation of chromatin structure, DNA replication, and gene expression. Interaction between cellular DNA and the nuclear matrix is mediated by putativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a58752d4d777475a90c4b031e280294
https://pubmed.ncbi.nlm.nih.gov/1617651

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