Zobrazeno 1 - 10
of 58
pro vyhledávání: '"D G, Shand"'
Autor:
R. E. Rangno, D. G. Shand
The relative contributions of tissue uptake and metabolism to the dose-dependent clearance of propranolol by the perfused rat liver have been investigated. When a small dose (1 mg) was added to a recycling system of 100 ml volume at a flow rate of 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69df749438a400cb0b7a20ad1d6974f5
https://doi.org/10.1159/000428677
https://doi.org/10.1159/000428677
Publikováno v:
Hypertension. 1:118-124
We investigated the effect of stimuli activate the sympathetic nervous system on plasma catecholamines, renin activity, urinary metanephrine and normetanephrine, and various hemodynamic parameters in normal subjects (NIs) and borderline hypertensive
Autor:
D G, Shand
Publikováno v:
Disease-a-Month. 20:1-31
Publikováno v:
Anesthesiology. 51:512-516
The effect of cardiopulmonary bypass on the plasma binding of propranolol was examined in seven patients. The fraction of propranolol free in plasma doubled, increasing from 6.6 to 13.5 per cent (P less than 0.001) following the administration of hep
Autor:
P A, Routledge, D G, Shand
Publikováno v:
Annual Review of Pharmacology and Toxicology. 19:447-468
The presystemic elimination of a large number of compounds is clearly established and represents a common and unavoidable cause of reduced bioavailability. The liver, intestine, and lungs have been identified as potential organs contributing to this
Publikováno v:
British Journal of Urology. 40:196-201
Publikováno v:
British Journal of Pharmacology. 47:595-605
1. Tendon jerk responses and H reflexes were recorded from conscious human volunteers before and after intravenous injection of methylamphetamine, thymoxamine and propranolol, and during intravenous infusion of noradrenaline.2. Methylamphetamine prod
Autor:
D. G. Shand, B. W. Payton
Publikováno v:
British Journal of Pharmacology and Chemotherapy. 28:23-34
Publikováno v:
Archives of Internal Medicine. 130:47-52
Autor:
D. J. Coltart, D. G. Shand
Publikováno v:
BMJ. 3:731-734
Plasma propranolol levels associated with reductions in endogenous and exogenous cardiac beta-stimulation were determined in normal people. The levels associated with a given degree of blockade of exercise-induced tachycardia were about three times g