Zobrazeno 1 - 10
of 71
pro vyhledávání: '"D G, Semenov"'
Autor:
D. G. Semenov, A. V. Belyakov
Publikováno v:
Neuroscience and Behavioral Physiology. 52:287-296
Publikováno v:
Journal of evolutionary biochemistry and physiology. 58(6)
Currently, there is a new surge of interest in the problem of hypoxia, almost lost in recent decades. Due to the fact that the circle of competent specialists in this field has significantly narrowed, it is necessary to carry out an intensive exchang
Autor:
A. V. Belyakov, D. G. Semenov
Publikováno v:
Advances in Gerontology. 9:190-196
The importance of research on neurological and mental changes in aged nonhuman primates, in particular, rhesus macaques (Macaca mulatta), is due to their genetic and physiological similarity with humans, which makes them preferable to rodents in prec
Autor:
D G, Semenov, A V, Belyakov
Publikováno v:
Advances in gerontology = Uspekhi gerontologii. 33(1)
Human aging is followed by the weakening of cognitive functions of the brain. The relevance of the study of this process as well as the search for ways of its medical correction increases due to the rise of the middle life span in developed countries
Autor:
D. G. Semenov, A. V. Belyakov
Publikováno v:
Neurochemical Journal. 11:213-220
Protein kinase B (Akt) is a key enzyme in one of many neuroprotective signaling cascades in neurons that are activated during preconditioning by episodes of moderate hypoxia/ischemia. However, the data on the involvement of this anti-apoptotic pathwa
Autor:
A V, Belyakov, D G, Semenov
Publikováno v:
Advances in gerontology = Uspekhi gerontologii. 31(6)
The importance of studying neurological and mental changes in aged non-human primates, in particular rhesus macaques (Macaca mulatta), is due to their genetic and physiological similarity with humans, which in preclinical studies of age-dependent cog
Autor:
D. G. Semenov, M. O. Samoilov, Alexandr V. Belyakov, Tatjana S. Glushchenko, Elzbieta Salinska, Jerzy W. Lazarewicz
Publikováno v:
Neurochemical Research. 40:2200-2210
The study assessed involvement of Ca(2+) signaling mediated by the metabotropic glutamate receptors mGluR1/5 in brain tolerance induced by hypoxic preconditioning. Acute slices of rat piriform cortex were tested 1 day after exposure of adult rats to
Publikováno v:
Neuroscience and Behavioral Physiology. 40:1012-1016
Hypoxia modifies glutamatergic signaling in the brain, inducing prolonged increases in intracellular Ca2+ levels. Depending on the severity of the applied hypoxia, the level and temporospatial profile of Ca2+ accumulation during reoxygenation trigger
Publikováno v:
Bulletin of Experimental Biology and Medicine. 147:185-188
Examination of fluorescent Ca(2+)-responses to stimulation by ionotropic glutamate receptor agonists in rat cerebral cortex slices, preconditioned with hypobaric hypoxia, has demonstrated different time course for up-regulation of their Ca(2+)-conduc
Autor:
K. N. Dudkin, A. A. Mokrushin, D. G. Semenov, D. Yu. Romanovskii, E. A. Milyakova, E. V. Lazarevich, M. O. Samoilov, E. I. Tyul’kova
Publikováno v:
Neuroscience and Behavioral Physiology. 33:1-11
A preventive short-term hypoxia (preconditioning) increases neuronal resistance against subsequent strong hypoxic effects. Literature review and authors' own data on molecular-cellular mechanisms of the hypoxic preconditioning, are presented. Partici