Zobrazeno 1 - 10
of 15
pro vyhledávání: '"D G, Khachidze"'
Autor:
M. Z. Gorgoshidze, D. G. Khachidze, J. Monaselidze, H. L. Margaryan, Eugene Kiziria, Vasil G. Bregadze, Nune Hakobyan, Maya Kiladze
Publikováno v:
American Journal of Analytical Chemistry. :744-748
It is known that at low concentrations of TMPyP4, this porphyrin predominantly intercalates between GC pairs at GC-rich sites of duplex DNA and G-quadruplexes of various constructions, and stabilizes these structures. However, there are still some ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44313e4f88b2ca9ce0cdbe1225603c75
https://doi.org/10.4236/ajac.2013.412090
https://doi.org/10.4236/ajac.2013.412090
Autor:
E. M. Lomidze, D. G. Khachidze, H. L. Margaryan, Nune Hakobyan, Maya Kiladze, Evgeni Kiziria, M. Z. Gorgoshidze, J. Monaselidze
Publikováno v:
American Journal of Analytical Chemistry. :698-703
CD spectra of (DNA-TOEPyP4) + ZnTOEPyP4, (DNA-ZnTOEPyP4) + TOEPyP4, and DNA + (TOEPyP4-ZnTO- EPyP4) complexes have been studied. It is shown that CD spectra of these triple complexes significantly differ from the DNA-TOEPyP4 and DNA-ZnTOEPyP4 double
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6efd2f3000d82e9d15707e85471f71ee
https://doi.org/10.4236/ajac.2012.310092
https://doi.org/10.4236/ajac.2012.310092
Autor:
Theimuraz A. Lezhava, E. M. Lomidze, M. Z. Gorgoshidze, J. Monaselidze, D. G. Khachidze, Maya Kiladze, Vasil G. Bregadze
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 108:127-131
The influence of new water soluble cationic metalloporphyrin Cu(II)TOEPyP(4) (meso-tetra-(4-N-oxyethylpyridyl)), analogue of Cu(II)TMPyP(4), on thermodynamic stability of DNA at various molar ratios of r = porphyrin/DNA b.p. (0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11ef58823ca0e17eb2e1aae0f9ea3243
https://doi.org/10.1007/s10973-011-1669-4
https://doi.org/10.1007/s10973-011-1669-4
Autor:
J. Monaselidze, G. Majagaladze, Yeva B. Dalyan, Vardanyan Vi, Sh Barbakadze, D. G. Khachidze, S. G. Haroutiunian, M. Z. Gorgoshidze, Y. Kalandadze
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 25:419-424
Thermodynamic parameters of melting process (DeltaHm, Tm, DeltaTm) of calf thymus DNA, poly(dA)poly(dT) and poly(d(A-C)).poly(d(G-T)) were determined in the presence of various concentrations of TOEPyP(4) and its Zn complex. The investigated porphyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac0bdaf44596fcddfae3e515f6e77a1
https://doi.org/10.1080/07391102.2008.10507190
https://doi.org/10.1080/07391102.2008.10507190
Autor:
Nune Hakobyan, D. G. Khachidze, H. L. Margaryan, M. Z. Gorgoshidze, Maya Kiladze, Eugene Kiziria, J. Monaselidze, Vasil G. Bregadze
Publikováno v:
Journal of biomolecular structuredynamics. 33(2)
Conformation changes of calf thymus DNA induced by nanomole concentrations of Co(+2) and TOEPyP4 and influence of this ion on porphyrin binding mode with DNA duplex were studied at two NaCl concentrations (10 and 100 mM) using circular dichroism spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bf778b352cfa802c0ee1f25ab15d5d
https://pubmed.ncbi.nlm.nih.gov/24428403
https://pubmed.ncbi.nlm.nih.gov/24428403
Publikováno v:
Journal of Biological Physics and Chemistry. 1:64-67
of calorimetric to effective (van™t Hoff) enthalpies gives the value 0.83 ±0.1 whichis fairly close to 1.0, indicating that the denaturation process of insulin proceedsas usually observed for compact globular proteins. The melting process of a me-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f30abc97e426112074d7cc12528d77
https://doi.org/10.4024/03kh01a.01.02
https://doi.org/10.4024/03kh01a.01.02
Publikováno v:
Journal of Thermal Analysis. 46:431-440
The influence of mitoxantron (M) and benz(a)pyrene (BP) on chromatin DNA in composition of spleen and liver tissues and cells of BALB/c mice were studied using a high-sensitive differential scanning microcalorimeter. It was established that BP can ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a033915e481f8ff70206c9314f0563ae
https://doi.org/10.1007/bf02135020
https://doi.org/10.1007/bf02135020
Autor:
D. G. Khachidze, E. M. Lomidze, T Lezhava, J. Monaselidze, Tinatin Jokhadze, M. Z. Gorgoshidze, V. Kh. Khavinson
Publikováno v:
Bulletin of experimental biology and medicine. 150(3)
Thermodynamic parameters of DNA melting in the presence of a peptide bronchogen in various concentrations were estimated on a differential scanning microcalorimeter. Bronchogen was shown to serve as a DNA-stabilizing agent. Bronchogen increased the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0480f9d462dc7937c5dd10953ddf5e04
https://pubmed.ncbi.nlm.nih.gov/21240358
https://pubmed.ncbi.nlm.nih.gov/21240358
Autor:
G. Majagaladze, D. G. Khachidze, Kvirikashvili Sh, Barbakadze Sh, Topchishvili L, J. Monaselidze
Publikováno v:
Biomacromolecules. 3(4)
The total value of heat (-Q) evolved by green-blue microalgae Spirulina platensis cells in a dark and stationary regime in the range of pH values 8.0-11.6 was determined. It was established that (-Q) reaches its maximum value at 360 +/- 40 J/g of dry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f1c1cd06b8257f17802208792a88e1
https://pubmed.ncbi.nlm.nih.gov/12099823
https://pubmed.ncbi.nlm.nih.gov/12099823
Autor:
D G, Khachidze, D R, Monaselidze
Publikováno v:
Biofizika. 45(2)
The independent melting of albumin, gamma-globulin, transferrin, and protease inhibitors in the composition of donor blood serum was studied by differential scanning microcalorimetry. It was found that the number of domains in gamma-globulin in donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d3cd4ee99ba57a0e9e7138158d97151
https://pubmed.ncbi.nlm.nih.gov/10776547
https://pubmed.ncbi.nlm.nih.gov/10776547