Zobrazeno 1 - 10
of 24
pro vyhledávání: '"D G, Fernig"'
Publikováno v:
interface
Phosphate and sulfate groups are integral to energy metabolism and introduce negative charges into biological macromolecules. One purpose of such modifications is to elicit precise binding/activation of protein partners. The physico-chemical properti
Publikováno v:
Open Biology, Vol 6, Iss 9 (2016)
Cellular adaptation to hypoxia occurs via a complex programme of gene expression mediated by the hypoxia-inducible factor (HIF). The oxygen labile alpha subunits, HIF-1α/-2α, form a heterodimeric transcription factor with HIF-1β and modulate gene
Externí odkaz:
https://doaj.org/article/4110075fee104a4196c9804c9cedbaf0
Publikováno v:
Royal Society Open Science, Vol 2, Iss 6 (2015)
Raster image correlation spectroscopy (RICS) measures the diffusion of fluorescently labelled molecules from stacks of confocal microscopy images by analysing correlations within the image. RICS enables the observation of a greater and, thus, more re
Externí odkaz:
https://doaj.org/article/3431f73e1dd047b280ac8f0e6b760125
Autor:
Y, Lemmer, S T, Thanyani, P J, Vrey, C H S, Driver, L, Venter, S, van Wyngaardt, A M C, ten Bokum, K I, Ozoemena, L A, Pilcher, D G, Fernig, A C, Stoltz, H S, Swai, J A, Verschoor
Publikováno v:
Methods in enzymology. 464
Antibodies to mycolic acid (MA) antigens can be detected as surrogate markers of active tuberculosis (TB) with evanescent field biosensors where the lipid antigens are encapsulated in liposomes. Standard immunoassay such as ELISA, where the lipid ant
Publikováno v:
Glycoconjugate journal. 18(7)
The dietary lectins, edible mushroom (ABL) and Jacalin (JAC) inhibit the proliferation of colonic cancer cells, whereas Amaranth (ACL) and peanut (PNA) stimulate their proliferation. All these lectins share as their preferred ligand the Thomsen-Fried
Publikováno v:
Journal of mammary gland biology and neoplasia. 6(3)
Proteoglycans consist of a core protein and an associated glycosaminoglycan (GAG) chain of heparan sulfate, chondroitin sulfate, dermatan sulfate or keratan sulfate, which are attached to a serine residue. The core proteins of cell surface proteoglyc
Publikováno v:
European journal of biochemistry. 268(16)
Hepatocyte growth factor/scatter factor (HGF/SF) is considered to be a mesenchymal-derived factor that acts via a dual system receptor, consisting of the MET receptor and proteoglycans present on adjacent epithelial cells. Surprisingly, HGS/SF stimul
Autor:
D G, Fernig
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 171
Publikováno v:
Journal of cellular physiology. 186(2)
Increased cell surface expression of the Thomsen-Friedenreich antigen (TF antigen, Galbeta1-3GalNAcalpha-) is a common feature in malignant and pre-malignant epithelia. Our previous studies have shown that dietary TF-binding lectins from peanut (Arac