Zobrazeno 1 - 10
of 15
pro vyhledávání: '"D Frank P, Larkin"'
Autor:
D. Frank P. Larkin, Alexander J. Smith, Mark Basche, Satoshi Kawasaki, Matthew J. Branch, Daniel Kampik, Robin R. Ali, Martha Robinson
Publikováno v:
Human gene therapy. 29(10)
Corneal epithelial dystrophies are typically characterized by symptoms such as pain, light sensitivity, and corneal opacification leading to impaired vision. The development of gene therapy for such conditions has been hindered by an inability to ach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b1894df234fb3ab4073ad9bd5e7e06
https://pubmed.ncbi.nlm.nih.gov/30070149
https://pubmed.ncbi.nlm.nih.gov/30070149
Autor:
Robin R. Ali, D. Frank P. Larkin, Mark Basche, Ulrich F O Luhmann, Alexander J. Smith, Anastasios Georgiadis, Daniel Kampik
Publikováno v:
Investigative Opthalmology & Visual Science. 60:3170
Purpose Endothelial cell density (ECD) is the principal factor determining the success of corneal transplants. Here we explored a strategy to increase corneal ECD in human explants via modulation of the ZO-1/ZONAB pathway. In multiple cell types, ZO-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f6b8d3ccba4df2331451fc30305295
https://doi.org/10.1167/iovs.18-26260
https://doi.org/10.1167/iovs.18-26260
Publikováno v:
Ocular Immunology and Inflammation. 18:162-171
Corneal transplantation has been performed successfully for over 100 years. Normally, HLA typing and systemic immunosuppressive drugs are not utilized, yet 90% of corneal allografts survive. In rodents, corneal allografts representing maximal histoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093a7cc50fa44d29b7d1f4ccce387976
https://doi.org/10.3109/09273948.2010.486100
https://doi.org/10.3109/09273948.2010.486100
Autor:
Navid Ardjomand, Gillian S. Patton, Myra O. McClure, Peng H. Tan, Sven C. Beutelspacher, Andrew J.T. George, D. Frank P. Larkin
Publikováno v:
Experimental Eye Research. 80:787-794
In this study we compare the ability of self-inactivating Human Immunodeficiency Virus 1 (HIV-1) and Equine Infectious Anaemia Virus (EIAV)-based vectors to mediate gene transfer to rabbit and human corneas and to a murine corneal endothelial cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa0b40a912a25350d55971e9c26cdbf
https://doi.org/10.1016/j.exer.2004.12.005
https://doi.org/10.1016/j.exer.2004.12.005
Autor:
Myra O. McClure, Giovanna Lombardi, Hans J. Stauss, Peter Mitchell, Mary A. Ritter, D. Frank P. Larkin, Yaohe Wang, Sven C. Beutelspacher, Shao-An Xue, Peng H. Tan, Andrew J.T. George, James C. McAlister
Publikováno v:
Blood. 105:3824-3832
Genetic modification of dendritic-cell (DC) function is an attractive approach to treat disease, either using mature DCs (mDCs) to immunize patients, or immature DCs (iDCs) to induce tolerance. Viral vectors are efficient at transducing DCs, and we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfddf077bb401c149955ae5aa8ffc3da
https://doi.org/10.1182/blood-2004-10-3880
https://doi.org/10.1182/blood-2004-10-3880
Publikováno v:
Journal of Cataract and Refractive Surgery. 31:297-301
Purpose To assess the effect of standardized, paired arcuate keratotomy (AK) on the change in astigmatism in postkeratoplasty eyes. Setting Moorfields Eye Hospital, London, United Kingdom. Methods A retrospective review was conducted of 20 eyes of 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec0a86586c822bb67a3f45ae4c77be2
https://doi.org/10.1016/j.jcrs.2004.07.025
https://doi.org/10.1016/j.jcrs.2004.07.025
Autor:
Linda A. Ficker, D. Frank P. Larkin, John K G Dart, Graham A Lee, Trevor Gray, Melville M. Matheson, Carlos Pavesio
Publikováno v:
Ophthalmology. 109:1178-1182
Objective: This study describes the clinical features, management, and outcome of 19 patients who had severe Acanthamoeba sclerokeratitis (ASK) unresponsive to conventional management, requiring systemic immunosuppression to control disease. Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60eb7f674898444a141cb0debcf5e04c
https://doi.org/10.1016/s0161-6420(02)01039-4
https://doi.org/10.1016/s0161-6420(02)01039-4
Publikováno v:
Eyecontact lens. 39(6)
Purpose Conjunctival papillomata are squamous epithelial tumors with a strong association with human papilloma virus (HPV) types 6 and 11. They are benign conjunctival tumors that can be treated by surgical excision. We report a case where topical im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193f4f1c35408d95def920497333e804
https://pubmed.ncbi.nlm.nih.gov/24136442
https://pubmed.ncbi.nlm.nih.gov/24136442
Autor:
Contributing Ophthalmologists, D. Frank P. Larkin, W. John Armitage, Stephen B. Kaye, Mark N. A. Jones, William Ayliffe
Publikováno v:
Investigative ophthalmologyvisual science. 50(12)
PURPOSE. To compare outcomes after penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) for keratoconus in the United Kingdom.METHODS. Patient outcome data were collected at the time of transplantation and at 1, 2, and 5 years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c648394535c4fffb8d38d4a082105d9
https://pubmed.ncbi.nlm.nih.gov/19661238
https://pubmed.ncbi.nlm.nih.gov/19661238