Zobrazeno 1 - 10
of 148
pro vyhledávání: '"D F Jelinek"'
Autor:
Stephanie A. Smoley, R Fonseca, Esteban Braggio, Scott VanWier, Neil E. Kay, Renee C. Tschumper, Traci Sassoon, John C. Byrd, Michael T. Barrett, D F Jelinek, Tait D. Shanafelt, D L Van Dyke, Jeanette E. Eckel-Passow
Publikováno v:
Leukemia. 26:1698-1701
Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse
Autor:
Colin L. Colby, Angela Dispenzieri, S. Vincent Rajkumar, Dirk R. Larson, Terry M. Therneau, Jerry A. Katzmann, L. Joseph Melton, D F Jelinek, Shaji Kumar, Rafael Fonseca, Arthur R. Bradwell, Raynell J. Clark, Robert A. Kyle
Publikováno v:
The Lancet. 375:1721-1728
Summary Background Monoclonal gammopathy of undetermined significance (MGUS) is defined by expression of heavy-chain immunoglobulin (IgH) and is the precursor lesion for 80% of cases of multiple myeloma. The remaining 20% are characterised by absence
Autor:
Zhen, Linqing1,2 (AUTHOR), Tang, Xinlu1 (AUTHOR), Xu, Zhengguo3 (AUTHOR), Huang, Yizhou1,2 (AUTHOR), Qian, Xiaohua1,2 (AUTHOR), Lin, Haiping4 (AUTHOR), Li, Chao3 (AUTHOR), Cui, Rong5 (AUTHOR), Fang, Hongsheng6 (AUTHOR), Yang, Hao1,2 (AUTHOR), Qiu, Jiani1,2 (AUTHOR), Fang, Zhaoqi7 (AUTHOR), Peng, Xiaohuan1,2 (AUTHOR), Jin, Yifeng5 (AUTHOR), Nie, Jianing7 (AUTHOR), Guo, Shiwei3 (AUTHOR), Wang, Yuguang3 (AUTHOR), Zhong, Ming4 (AUTHOR) drzhongming1966@163.com, Gu, Hongchen1,2 (AUTHOR) hcgu@sjtu.edu.cn, Xu, Hong1,2 (AUTHOR) xuhong@sjtu.edu.cn
Publikováno v:
Advanced Science. 9/4/2024, Vol. 11 Issue 33, p1-16. 16p.
Autor:
Stephen M. Ansell, Linda Wellik, D F Jelinek, C. F. Bennett, Bonnie K. Arendt, Ellen D. Remstein, Adele K. Fielding, Deanna M. Grote, Anne J. Novak
Publikováno v:
Leukemia. 18:616-623
Survivin is a member of the inhibitor of apoptosis protein (IAP) family and functions both as an apoptosis inhibitor and a regulator of cell division. Survivin overexpression is common in many human tumors and correlates with survival in large cell n
Autor:
S. M. Ansell, Renee C. Tschumper, A Velazquez-Dones, T. E. Witzig, Kyle G. Howell, D F Jelinek, Bonnie K. Arendt
Publikováno v:
Leukemia. 16:2142-2147
Interleukin 6 (IL-6) is known to play an important role in the biology of the malignant plasma cells in multiple myeloma. In an effort to better understand IL-6 stimulated myeloma cell growth, we have performed gene expression profiling to identify I
Autor:
Susan Geyer, D F Jelinek, Neil E. Kay, Nancy D. Bone, C A Hanson, Gordon W. Dewald, K. H. Howell, Renee C. Tschumper
Publikováno v:
Leukemia. 16:911-919
Initial work has shown that clonal B cells from B-chronic lymphocytic leukemia (B-CLL) are able to synthesize pro-angiogenic molecules. In this study, our goal was to study the spectrum of angiogenic factors and receptors expressed in the CLL B cell.
Publikováno v:
The Journal of Immunology. 159:487-496
Insulin-like growth factors (IGF-I, IGF-II) have long been recognized as important mitogens in many types of malignancies. Because the role of IGFs in growth control of myeloma cells has not been extensively examined, we have used a panel of IL-6-res
Autor:
K M Aagaard-Tillery, D F Jelinek
Publikováno v:
The Journal of Immunology. 157:2769-2778
Evidence supporting the importance of the 3-phosphoinositide signaling pathway in lymphocyte activation is rapidly accumulating. In our study, we assessed the effects of two PI 3-kinase inhibitors, wortmannin and LY294002, on T cells as a means to an
Autor:
K M Aagaard-Tillery, D F Jelinek
Publikováno v:
The Journal of Immunology. 156:4543-4554
A variety of signals, mediated via either the B cell Ag receptor (BCR), or non-BCR molecules such as CD40 or cytokine receptors, have been shown to be crucial for the regulation of B cell survival, growth, and differentiation. Although it is clear th
Autor:
K M Aagaard-Tillery, D F Jelinek
Publikováno v:
The Journal of Immunology. 155:3297-3307
The state of B cell maturation profoundly influences the outcome, i.e., activation, growth arrest, or programmed cell death, of a variety of stimuli, including the calcium ionophore, ionomycin. Initial studies confirmed the observation that cell line