Zobrazeno 1 - 10 of 12 pro vyhledávání: '"D F Holmes"'
2
Growth of sea cucumber collagen fibrils occurs at the tips and centers in a coordinated manner
Autor: J A, Trotter, J A, Chapman, K E, Kadler, D F, Holmes
Publikováno v: Journal of molecular biology. 284(5)
Collagen fibrils are the principle source of mechanical strength in the mutable dermis of the sea cucumber Cucumaria frondosa. To obtain information about the mechanism by which collagen molecules self-assemble into fibrils, we have isolated single i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f684fe12a1c18267c181d92d25ff3078
https://pubmed.ncbi.nlm.nih.gov/9878360
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3
Assembly in vitro of thin and thick fibrils of collagen II from recombinant procollagen II. The monomers in the tips of thick fibrils have the opposite orientation from monomers in the growing tips of collagen I fibrils
Autor: A, Fertala, D F, Holmes, K E, Kadler, A L, Sieron, D J, Prockop
Publikováno v: The Journal of biological chemistry. 271(25)
Human type II procollagen was prepared in a recombinant system and cleaved to pC-collagen II by procollagen N-proteinase. The pC-collagen II was then used as a substrate to generate collagen II fibrils by cleavage with procollagen C-proteinase at 37
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c68821bb3f8fcb65830405efa4270b3
https://pubmed.ncbi.nlm.nih.gov/8662997
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4
Implications of the EC Manual Handling of Loads Directive for nurse managers
Autor: D F, Holmes
Publikováno v: British journal of nursing (Mark Allen Publishing). 3(22)
The European Community has introduced new regulations designed to stop people being injured when moving loads at work. These rules came into effect on 1 January 1993. So far, however, many managers have done nothing about them. If nurses are injured,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52238cf68f5f56e30d58648c5a0ff66e
https://pubmed.ncbi.nlm.nih.gov/7866014
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5
Ehlers-Danlos syndrome type VIIB. Morphology of type I collagen fibrils formed in vivo and in vitro is determined by the conformation of the retained N-propeptide
Autor: D F, Holmes, R B, Watson, B, Steinmann, K E, Kadler
Publikováno v: The Journal of biological chemistry. 268(21)
Previously we showed that fibrils generated from collagen and pNcollagen-ex6 from fibroblasts of an individual with Ehlers-Danlos syndrome (EDS) type VIIB were hieroglyphic in cross-section and all N-propeptides were located at the fibril surface. Hi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c878b11027633307f81f994735aab9d0
https://pubmed.ncbi.nlm.nih.gov/8340401
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6
Ehlers Danlos syndrome type VIIB. Incomplete cleavage of abnormal type I procollagen by N-proteinase in vitro results in the formation of copolymers of collagen and partially cleaved pNcollagen that are near circular in cross-section
Autor: R B, Watson, G A, Wallis, D F, Holmes, D, Viljoen, P H, Byers, K E, Kadler
Publikováno v: The Journal of biological chemistry. 267(13)
We have shown that a child with Ehlers Danlos syndrome (EDS) type VII has a G to A transition at the first nucleotide of intron 6 in one of her COL1A2 alleles. Half of the cDNA clones prepared from the proband's pro alpha 2(I) mRNA lacked exon 6. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b60bcbd0b312da1181af69528d33fbc7
https://pubmed.ncbi.nlm.nih.gov/1577745
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7
Response of dairy calves to vaccinia viruses that express foreign genes
Autor: C M Geissinger, E Paoletti, W P Higgins, M Perkus, F W Scott, S Mercer, J H Gillespie, D F Holmes
Publikováno v: Journal of Clinical Microbiology. 23:283-288
Repeated intradermal inoculations of calves with wild-type vaccinia virus and recombinant vaccinia viruses expressing human hepatitis B virus surface antigen and herpes simplex virus, type 1, glycoprotein D produced characteristic pox lesions at each
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bde8722a2e2fa9333e6bb29a8a9e4b5
https://doi.org/10.1128/jcm.23.2.283-288.1986
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9
Lyophilized hyperimmune equine serum as a source of antibodies for neonatal foals
Autor: S C, Burton, H F, Hintz, M J, Kemen, D F, Holmes
Publikováno v: American journal of veterinary research. 42(2)
In a study with 15 neonatal foals (5 per treatment group), foals were fed within 4 hours of birth as follows: 250 ml of colostrum, 250 ml of lyophilized serum reconstituted at 5 times the original concentration, or 250 ml of a mixture (1:1) of colost
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ad5f55ca3d0fba6d963945f26904df3
https://pubmed.ncbi.nlm.nih.gov/6266291
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10
Collagen fibrillogenesis in vitro: an investigation of the thermal memory effect and of the early events occurring during fibril assembly using dynamic light scattering
Autor: T.A. King, K. J. Payne, D. F. Holmes
Publikováno v: Biopolymers. 25(7)
Dynamic light scattering has been used to characterize a variety of lathyritic rat skin collagen solutions. The technique was used to monitor the onset of fibril assembly in vitro and to investigate the thermal memory effect. Although the incorporati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8cda2343092b1cf82e4c7af937ad46
https://pubmed.ncbi.nlm.nih.gov/3741991
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