Zobrazeno 1 - 10
of 142
pro vyhledávání: '"D F, van Helden"'
Autor:
Derek R. Laver, Kafa Walweel, Angela F. Dulhunty, Peter C. M. Molenaar, D F van Helden, A. Denniss, C.G. dos Remedios, Mohammad S. Imtiaz, Nicole A. Beard
Publikováno v:
Journal of Molecular and Cellular Cardiology. 104:53-62
Highlights • Human failing heart ryanodine receptor 2 (RyR2) Ca2+ release channels display an altered regulation to cytoplasmic Ca2+. • Alterations in failing heart RyR2 function are correlated with higher RyR2 phosphorylation and thiol modificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a9d9ea593d1482d8e1df99ff5183561
https://doi.org/10.1016/j.yjmcc.2017.01.016
https://doi.org/10.1016/j.yjmcc.2017.01.016
Autor:
K, Walweel, P, Molenaar, M S, Imtiaz, A, Denniss, C, Dos Remedios, D F, van Helden, A F, Dulhunty, D R, Laver, N A, Beard
Publikováno v:
Journal of molecular and cellular cardiology. 104
Heart failure is a multimodal disorder, of which disrupted CaTo assess CaThe function of RyR2 from left ventricular samples was assessed using lipid bilayer single-channel measurements, whilst RyR2 modification and protein:protein interactions were d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f41d0a1dbab82f9da7275259757cb065
https://pubmed.ncbi.nlm.nih.gov/28131631
https://pubmed.ncbi.nlm.nih.gov/28131631
Autor:
R. B. de Oliveira, Fernanda S. Gravina, Karen P Kerr, Phillip Jobling, D F van Helden, Helena C. Parkington
Publikováno v:
Experimental Physiology. 96:949-956
Oxytocin is known to play important roles in uterine contractions, mediated at least in part by increasing intracellular Ca2+ concentration ([Ca2+]i), through enhancing extracellular Ca2+ entry and Ca2+ release from the sarcoplasmic reticulum, proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607a492a7915c19eac7cced637509a84
https://doi.org/10.1113/expphysiol.2011.058388
https://doi.org/10.1113/expphysiol.2011.058388
Publikováno v:
Heart, Lung and Circulation. 27:S182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc512afb2c08c202d3e7de05b979b48b
https://doi.org/10.1016/j.hlc.2018.06.313
https://doi.org/10.1016/j.hlc.2018.06.313
Autor:
D F, Van Helden, J, Zhao
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 27:1014-1018
1. Experimental findings in the past decade have greatly advanced present understanding of electrical/mechanical rhythmicities in smooth muscle, including vasomotion. Lymphatic vessels show strong vasomotor activity and have provided a key experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0a5f0d643c5562baeea76be2ad4ddb
https://doi.org/10.1046/j.1440-1681.2000.03368.x
https://doi.org/10.1046/j.1440-1681.2000.03368.x
Publikováno v:
The Journal of Physiology. 524:245-265
1 Intracellular recordings made in single bundle strips of a visceral smooth muscle revealed rhythmic spontaneous membrane depolarizations termed slow waves (SWs). These exhibited ‘pacemaker’ and ‘regenerative’ components composed of summatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee08b05edf9fa0c65eb9b76ceec2ab4c
https://doi.org/10.1111/j.1469-7793.2000.00245.x
https://doi.org/10.1111/j.1469-7793.2000.00245.x
Publikováno v:
The Journal of Physiology. 493:563-575
1. Endothelial control of the rate of constrictions and the underlying pacemaker potentials has been studied in vitro in guinea-pig mesenteric lymphatic vessels. 2. ACh stimulated 60% of intraluminally perfused vessels to slow or abolish lymphatic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1927a93bc426921c31a2744adfead28
https://doi.org/10.1113/jphysiol.1996.sp021404
https://doi.org/10.1113/jphysiol.1996.sp021404
Publikováno v:
Biochemical and Biophysical Research Communications. 219:219-226
The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines. Apoptosis was confirmed after drug treatment of the cells by the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da91c9880dcbd9f4206a5c3168f1bd50
https://doi.org/10.1006/bbrc.1996.0208
https://doi.org/10.1006/bbrc.1996.0208
Autor:
C.G. dos Remedios, Derek R. Laver, Ye Wint Oo, Peter C. M. Molenaar, Bjorn C. Knollmann, Kafa Walweel, D F van Helden
Publikováno v:
Heart, Lung and Circulation. 26:S163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b05a74df5b6cd139c2be785c85f988f
https://doi.org/10.1016/j.hlc.2017.06.273
https://doi.org/10.1016/j.hlc.2017.06.273
Autor:
James A. Brock, D F van Helden
Publikováno v:
Pflügers Archiv. 430:901-908
Excitatory junction potentials (EJPs) were examined using intracellular recording techniques in mesenteric arteries isolated from 12- to 15-week-old spontaneously hypertensive (SHR), Wistar Kyoto (WKY) and Sprague Dawley (SD) rats. The amplitudes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e061c808c8cea48fd43cba8a31c7c8
https://doi.org/10.1007/bf01837403
https://doi.org/10.1007/bf01837403