Výsledky vyhledávání - "D F, McDermott"

Akademický článek

Overall survival by clinical risk category for high dose interleukin-2 (HD IL-2) treated patients with metastatic renal cell cancer (mRCC): data from the PROCLAIMSM registry

Autor: M. Fishman, J. P. Dutcher, J. I. Clark, A. Alva, G. P. Miletello, B. Curti, Neeraj Agarwal, R. Hauke, K. M. Mahoney, H. Moon, J. Treisman, S. S. Tykodi, G. Daniels, M. A. Morse, M. K. K. Wong, H. Kaufman, N. Gregory, D. F. McDermott

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)

Abstract Background Prognostic scoring systems are used to estimate the risk of mortality from metastatic renal cell carcinoma (mRCC). Outcomes from different therapies may vary within each risk group. These survival algorithms have been applied to a

Externí odkaz: https://doaj.org/article/7d478c6399ec4cf190bfe0d15deaaa9b

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Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis

Autor: Fred D. Finkelman, D F McDermott, G D Miralles, Henry W. Murray, Mark Y. Stoeckle

Publikováno v: Infection and Immunity. 62:1058-1063

In experimental Leishmania donovani infection in BALB/c mice, initial susceptibility gives way to T-cell-dependent acquired resistance and eventual control over visceral infection. Since various cytokines appear to underlie the host response to Leish

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5862406821c91f1a04d18ece709795d
https://doi.org/10.1128/iai.62.3.1058-1063.1994

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Role and effect of IL-2 in experimental visceral leishmaniasis

Autor: H W Murray, G D Miralles, M Y Stoeckle, D F McDermott

Publikováno v: The Journal of Immunology. 151:929-938

In experimental visceral leishmaniasis, acquired resistance is T cell-dependent, involves IFN-gamma-activated macrophages, and is expressed in the tissues by granuloma formation. Resistance also correlates with Ag-stimulated IL-2 secretion; therefore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9befd5744a986e7c514ae8b8b09c3fee
https://doi.org/10.4049/jimmunol.151.2.929

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A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin 2, and interferon alpha-2B in patients with metastatic melanoma

Autor: D F, McDermott, J W, Mier, D P, Lawrence, M R, van den Brink, M A, Clancy, K M, Rubin, M B, Atkins

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)

In an effort to develop a biochemotherapy regimen for metastatic melanoma suitable for testing in a cooperative group setting, we modified the concurrent biochemotherapy regimen of S. S. Legha et al. (J. Clin. Oncol., 16: 1752-1759, 1998) by providin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::626cfcbd845f07c1a0cc0e9a8f8fcdc3
https://pubmed.ncbi.nlm.nih.gov/10873069

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A two-part phase I trial of high-dose interleukin 2 in combination with soluble (Chinese hamster ovary) interleukin 1 receptor

Autor: D F, McDermott, E G, Trehu, J W, Mier, D, Sorce, W, Rand, L, Ronayne, K, Kappler, M, Clancy, M, Klempner, M B, Atkins

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(5)

Our purpose was to determine the maximum tolerated dose and toxicity associated with soluble Chinese hamster ovary [s(CHO)] recombinant human interleukin (IL) 1 receptor (IL-1R; Immunex, Seattle, WA) administration in humans and to determine the effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b7510e38c0bf10676a14c185f5fb549
https://pubmed.ncbi.nlm.nih.gov/9607578

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Multiple host defense defects in failure of C57BL/6 ep/ep (pale ear) mice to resolve visceral Leishmania donovani infection

Autor: June Hariprashad, Mark Y. Stoeckle, D F McDermott, Henry W. Murray

Publikováno v: Infection and immunity. 64(1)

Euthymic C57BL/L ep/ep (pale ear [PE]) mice halt the visceral replication of intracellular Leishmania donovani but fail to properly resolve infection. A previous study identified an isolated defect in tissue granuloma formation in these mice; CD4+ an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea69434bb1e55d176065f6127121c65
https://pubmed.ncbi.nlm.nih.gov/8557335

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Updated results of a randomized phase II study comparing two schedules of temozolomide in combination with sorafenib in patients with advanced melanoma

Autor: R. Amaravadi, L. M. Schuchter, D. F. McDermott, A. Kramer, L. Giles, A. B. Troxel, C. A. Medina, K. L. Nathanson, P. J. O'Dwyer, K. T. Flaherty

Publikováno v: Journal of Clinical Oncology. 25:8527-8527

8527 Background: The preliminary results for 90 patients (pt) on this 4-arm phase II trial testing sorafenib (SO), an oral Raf kinase/VEGFR2 inhibitor, and temozolomide (TEM) in pt with metastatic melanoma (MM) were presented in 2006. Since then 88%

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fe3cc370066d15511cee848147edfc1
https://doi.org/10.1200/jco.2007.25.18_suppl.8527

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