Zobrazeno 1 - 10
of 217
pro vyhledávání: '"D F, Horrobin"'
Autor:
D. F. Horrobin
I am becoming increasingly disturbed by the lack of under standing of science revealed by politicians, industrialists and the general public. I am also concerned about the widespread mis use of the word'scientific'which is more and more being use
Publikováno v:
Journal of Nutritional Medicine. 4:327-349
We have reviewed the evidence for changes in lipids in blood and brain in ageing animals, in ageing humans and in humans with Alzheimer's disease. Studies of anti-oxidant enzymes in isolation are unsatisfactory and other markers of the oxidation/redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929af17243cb4106e63a1a38a05ed3ae
https://doi.org/10.3109/13590849409007232
https://doi.org/10.3109/13590849409007232
Autor:
D F Horrobin
Publikováno v:
The American Journal of Clinical Nutrition. 57:732S-737S
Linoleic acid is the main dietary essential fatty acid (EFA). To be fully utilized by the body, it must be metabolized to a range of other substances. The first step in this pathway is delta-6-desaturation to gamma-linolenic acid (GLA). This step is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f211dc446513c6b5067b3312f7dacc0
https://doi.org/10.1093/ajcn/57.5.732s
https://doi.org/10.1093/ajcn/57.5.732s
Publikováno v:
Nutrition Research. 11:439-448
Evidence has shown that dietary supplementation with virgin olive oil (OLO) lowers plasma cholesterol (CH) level. The present study demonstrated in animals that OLO supplementation also suppresses the conversion of 20:3n-6 to 20:4n-6 (Δ 5 desaturati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0704e6f3e672b5f02c1d9b721621a09
https://doi.org/10.1016/s0271-5317(05)80006-5
https://doi.org/10.1016/s0271-5317(05)80006-5
Autor:
W. S. Douglas, J.L. Burton, David Gould, J.C.M. Stewart, C. T. C. Kennedy, R. Lindskov, P.F. Morse, T. C. Hindson, M. Moss, C. E. H. Grattan, J. Anderson, A. M. M. Strong, D. F. Horrobin, Christer T. Jansén
Publikováno v:
Journal of Nutritional Medicine. 2:9-15
An open, uncontrolled trial of the value of a selected variety of evening primrose oil (Epogamr` Scotia Pharmaceuticals Ltd, Guildford, Surrey GU1 1BA) in severe and moderately severe atopic dermatitis was conducted in 13 centres. Evening primrose oi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4439246c19f53911621902fcc7d41352
https://doi.org/10.3109/13590849109084095
https://doi.org/10.3109/13590849109084095
Autor:
D. F. Horrobin
Publikováno v:
JAMA: The Journal of the American Medical Association. 263:1438-1441
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ebd873613179a4e5693d6195a2be91
https://doi.org/10.1001/jama.263.10.1438
https://doi.org/10.1001/jama.263.10.1438
Autor:
D. F. Horrobin
Publikováno v:
Journal of Nutritional Medicine. 1:145-151
There is evidence of a close interrelationship between essential fatty acid (EFA) metabolism and the ability to respond to viral infections. EFAs are required to enable interferon to exert its antiviral effects. Viral infections both in vivo and in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7da3aa11ab1061fdb2ba760eb2ee7b82
https://doi.org/10.3109/13590849009003150
https://doi.org/10.3109/13590849009003150
Publikováno v:
Pharmacopsychiatry. 39(3)
Background Increased interleukin-1beta (IL-1) in the brain and periphery has been associated with neurodegenerative and psychiatric disorders. However, results from different IL-1 sources, administrating routes, doses and treatment duration were inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b52f8ebd0bb61b009bd4c21f16c0cd
https://pubmed.ncbi.nlm.nih.gov/16721697
https://pubmed.ncbi.nlm.nih.gov/16721697
Publikováno v:
Molecular psychiatry. 9(6)
Central or peripheral administration of the proinflammatory cytokine interleukin (IL)-1beta can impair performance on spatial memory tasks and also elevate circulating concentration of corticosterone. The present experiment provides independent confi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c15510e15e848173cc1aa5ca45ffae
https://pubmed.ncbi.nlm.nih.gov/14699427
https://pubmed.ncbi.nlm.nih.gov/14699427
Publikováno v:
Bratislavske lekarske listy. 103(3)
Senescence is associated with a decreased activity of enzyme delta-6 desaturase, which converts linoleic acid to gamma-linolenic acid. This enzymatic defect may alter the composition of plasma and membrane lipids, and influences the biosynthesis of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::759146571e844d3799b869f307a9b800
https://pubmed.ncbi.nlm.nih.gov/12190041
https://pubmed.ncbi.nlm.nih.gov/12190041