Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D F, Gudbjartsson"'
Autor:
B. A. Jonsson, G. Bjornsdottir, T. E. Thorgeirsson, L. M. Ellingsen, G. Bragi Walters, D. F. Gudbjartsson, H. Stefansson, K. Stefansson, M. O. Ulfarsson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Machine learning algorithms can be trained to estimate age from brain structural MRI. Here, the authors introduce a new deep-learning-based age prediction approach, and then carry out a GWAS of the difference between predicted and chronological age,
Externí odkaz:
https://doaj.org/article/213453bfd3e54ce99b57019d4343efca
Autor:
D B, Hancock, Y, Guo, G W, Reginsson, N C, Gaddis, S M, Lutz, R, Sherva, A, Loukola, C C, Minica, C A, Markunas, Y, Han, K A, Young, D F, Gudbjartsson, F, Gu, D W, McNeil, B, Qaiser, C, Glasheen, S, Olson, M T, Landi, P A F, Madden, L A, Farrer, J, Vink, N L, Saccone, M C, Neale, H R, Kranzler, J, McKay, R J, Hung, C I, Amos, M L, Marazita, D I, Boomsma, T B, Baker, J, Gelernter, J, Kaprio, N E, Caporaso, T E, Thorgeirsson, J E, Hokanson, L J, Bierut, K, Stefansson, E O, Johnson
Publikováno v:
Molecular psychiatry
Cigarette smoking is a leading cause of preventable mortality worldwide. Nicotine dependence, which reduces the likelihood of quitting smoking, is a heritable trait with firmly established associations with sequence variants in nicotine acetylcholine
Autor:
Nora Franceschini, Rico Rueedi, Gerardo Heiss, Behrooz Z. Alizadeh, Marike Gabrielson, Henry Völzke, Daniela Ruggiero, Judith S. Brand, Stig E. Bojesen, Iffat Rahman, Fergus J. Couch, Patrick Sulem, Harold Snieder, Jenny Chang-Claude, Caterina Barbieri, Ute Hamann, Hinds D, Pascal Guénel, Amanda B. Spurdle, Paul M. Ridker, Ulla Sovio, Roger L. Milne, Hamdi Mbarek, H Brenner, Hilary K. Finucane, Maristella Steri, Lude Franke, Emmi Tikkanen, Ivana Kolcic, Vitart, Ken K. Ong, Alison M. Dunning, Aarno Palotie, Caroline Hayward, Jouke J. Hottenga, Abhishek Sarkar, Stefania Lenarduzzi, Nicholas G. Martin, Katharina E. Schraut, Eva Albrecht, Hiltrud Brauch, Lisette Stolk, Joop S.E. Laven, Penelope A. Lind, Ilaria Gandin, Patrik K. E. Magnusson, Ellen A. Nohr, Tanguy Corre, Jing Hua Zhao, N J Timpson, Jenny A. Visser, Harald Grallert, P. A. Fasching, Susan M. Ring, Stöckl D, Grant W. Montgomery, Marzyeh Amini, Velez Edwards Dr, Thomas Meitinger, Qinghua Wang, David Karasik, Daniel I. Chasman, Nicholas J. Wareham, Alexander Teumer, Mellissa C. Southey, Kathryn L. Lunetta, S. E. Medland, Dieter Flesch-Janys, Maartje J. Hooning, Lili Milani, D Lambrechts, Ozren Polasek, Po-Ru Loh, James F. Wilson, Campbell A, Julian Peto, Ellen W. Demerath, Christian Gieger, de Geus Ej, Cox A, Javier Benítez, Mitul Shah, Eric Boerwinkle, Matthias W. Beckmann, Thorsteindottir U, Julie E. Buring, De Vivo I, Hannes Helgason, Paolo Radice, Tracy A. O'Mara, L. J. Launer, D. F. Gudbjartsson, Frits R. Rosendaal, C.A. Hartman, Stefania Bandinelli, Felix R. Day, Lynda M. Rose, van Dijk Kw, Natalia Perjakova, Anneli Pouta, Igor Rudan, Sven Bergmann, Kamila Czene, Georgia Chenevix-Trench, Pau Navarro, Sean Whalen, Heli Nevanlinna, Teresa Nutile, Diana L. Cousminer, Albert V. Smith, Massimo Mangino, Uwe Völker, Michela Traglia, Lindsay Fernández-Rhodes, Ayush Giri, Linda Broer, Albertine J. Oldehinkel, Isabel dos-Santos-Silva, Peter Vollenweider, Jian'an Luan, Nancy L. Pedersen, Irene L. Andrulis, Reedik Mägi, Robert Winqvist, Gonneke Willemsen, John L. Hopper, Gudnason, Marjanka K. Schmidt, David G. Hunter, Robert A. Scott, T.B. Harris, Joanne M. Murabito, David J. Porteous, Harry Campbell, Eleonora Porcu, D.I. Boomsma, Thibaud Boutin, M. A. Ikram, Doug Easton, Magdalena Zoledziewska, Meir J. Stampfer, Katherine S. Pollard, Eulalia Catamo, Tõnu Esko, M-R Jarvelin, Laura Crisponi, Claudia Langenberg, Marek Zygmunt, Antonietta Robino, Emily Hallberg, Manjeet K. Bolla, Ruth Ks, Bruce H W Wolffenbuttel, Lavinia Paternoster, Tyrer Jp, P. Kraft, George Davey-Smith, Robert Karlsson, Graham G. Giles, Jingmei Li, Pharoah Pd, Segrè Av, Marina Ciullo, Perry, Brumat Marco, Peter K. Joshi, Chunyan He, Sara Lindström, Joe Dennis, Thérèse Truong, Yongmei Liu, Anna Marie Mulligan, Mike A. Nalls, Cinzia Sala, K. Stefansson, Murray A, Debbie A Lawlor, Tung Jy, Deborah J. Thompson, Dennis O. Mook-Kanamori, Daniela Toniolo, Luigi Ferrucci, Peter Devilee, S. Chanock, Cristina Menni, George McMahon, Murielle Bochud, A. Metspalu, Tomohiro Tanaka, E. Widen, Hae Kyung Im, Dale R. Nyholt, Ilja M. Nolte, Thomas Brüning, Christina Meisinger, Annette Peters, Kyriaki Michailidou, Per Hall, Rossella Sorice, Genevieve Lachance, Johan G. Eriksson, Francesco Cucca, A.G. Uitterlinden, Z. Kutalik, Mark I. McCarthy, Frank B. Hu, Konstantin Strauch, Tim D. Spector, Elisabeth Altmaier, S. Ulivi, Alkes L. Price, Arto Mannermaa, Raymond Noordam, de Mutsert R
The timing of puberty is a highly polygenic childhood trait that is epidemiologically associated with various adult diseases. Here, we analyse 1000-Genome reference panel imputed genotype data on up to ~370,000 women and identify 389 independent sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b624998b4a1e4c46cc9cbd86bba0b543
Autor:
A. G. Uitterlinden, S. Y. Shin, Massimo Mangino, N. Dahmen, Lambertus A. Kiemeney, Dorret I. Boomsma, Arfan Ikram, B.A. Oostra, D. F. Gudbjartsson, Germaine C. Verwoert, Aravinda Chakravarti, Vilmundur Gudnason, Stefan Walter, J. C. Keers, Unnur Thorsteinsdottir, F. J.A. Van Rooij, Henning Tiemeier, Grant W. Montgomery, P. Sulem, Rajesh Rawal, Tim D. Spector, Erich Wichmann, Enda M. Byrne, Nicholas G. Martin, J. C. M. Witteman, Sebastian E. Baumeister, Najaf Amin, Christopher J Hammond, C.M. van Duijn, Astrid Petersmann, Julie Johnson, Aaron Isaacs, Georgia Chenevix-Trench, A. C. J. W. Janssens, Alexander Teumer, J. M. Vink, Ilja M. Nolte, Y S Aulchenko, Angela Doering, Linda Broer, A. C. Heath, B. H.R. Wolfenbuttel, Bruce M. Psaty, Harold Snieder, Fernando Rivadeneira, Kari Stefansson, Albert Hofman, Naomi R. Wray, J. J. Hottenga, Hans-Jörgen Grabe, Rainer Biffar, Daniel Levy
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, 17(11), 1116-1129. Nature Publishing Group
Amin, N, Byrne, E, Johnson, J, Chenevix-Trench, G, Walter, S, Nolte, I M, Vink, J M, Rawal, R, Mangino, M, Teumer, A, Keers, J C, Verwoert, G, Baumeister, S, Biffar, R, Petersmann, A, Dahmen, N, Doering, A, Isaacs, A, Broer, L, Wray, N R, Montgomery, G W, Levy, D, Psaty, B M, Gudnason, V, Chakravarti, A, Sulem, P, Gudbjartsson, D F, Kiemeney, L A, Thorsteinsdottir, U, Stefansson, K, van Rooij, F J A, Aulchenko, Y S, Rivadeneira, F, Hofman, A, Uitterlinden, A G, Hammond, C J, Shin, S Y, Arfan Ikram, M, Witteman, J C M, Janssens, A C J W, Snieder, H, Tiemeier, H, Wolfenbuttel, B H R, Oostra, B A, Heath, A C, Wichmann, E, Spector, T D, Grabe, H J, Boomsma, D I, Martin, N G & van Duijn, C M 2012, ' Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM ', Molecular Psychiatry, vol. 17, no. 11, pp. 1116-1129 . https://doi.org/10.1038/mp.2011.101
Molecular Psychiatry, 17, 11, pp. 1116-29
Molecular Psychiatry, 17(11), 1116-29. Nature Publishing Group
Molecular Psychiatry, 17, 1116-29
Molecular Psychiatry; Vol 17
Molecular Psychiatry, 17(11), 1116-1129. Nature Publishing Group
Amin, N, Byrne, E, Johnson, J, Chenevix-Trench, G, Walter, S, Nolte, I M, Vink, J M, Rawal, R, Mangino, M, Teumer, A, Keers, J C, Verwoert, G, Baumeister, S, Biffar, R, Petersmann, A, Dahmen, N, Doering, A, Isaacs, A, Broer, L, Wray, N R, Montgomery, G W, Levy, D, Psaty, B M, Gudnason, V, Chakravarti, A, Sulem, P, Gudbjartsson, D F, Kiemeney, L A, Thorsteinsdottir, U, Stefansson, K, van Rooij, F J A, Aulchenko, Y S, Rivadeneira, F, Hofman, A, Uitterlinden, A G, Hammond, C J, Shin, S Y, Arfan Ikram, M, Witteman, J C M, Janssens, A C J W, Snieder, H, Tiemeier, H, Wolfenbuttel, B H R, Oostra, B A, Heath, A C, Wichmann, E, Spector, T D, Grabe, H J, Boomsma, D I, Martin, N G & van Duijn, C M 2012, ' Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM ', Molecular Psychiatry, vol. 17, no. 11, pp. 1116-1129 . https://doi.org/10.1038/mp.2011.101
Molecular Psychiatry, 17, 11, pp. 1116-29
Molecular Psychiatry, 17(11), 1116-29. Nature Publishing Group
Molecular Psychiatry, 17, 1116-29
Molecular Psychiatry; Vol 17
Coffee consumption is a model for addictive behavior. We performed a meta-analysis of genome-wide association studies (GWASs) on coffee intake from 8 Caucasian cohorts (N = 18 176) and sought replication of our top findings in a further 7929 individu
Autor:
S F, Grant, G, Thorleifsson, M L, Frigge, J, Thorsteinsson, B, Gunnlaugsdóttir, A J, Geirsson, M, Gudmundsson, A, Vikingsson, K, Erlendsson, J, Valsson, H, Jónsson, D F, Gudbjartsson, K, Stefánsson, J R, Gulcher, K, Steinsson
Publikováno v:
Arthritis and rheumatism. 44(10)
Rheumatoid arthritis (RA) is the most common form of inflammatory arthritis. Although there is a large body of evidence suggesting that RA is immune mediated, the etiology remains unresolved. Twin studies have shown disease concordance rates of appro