Výsledky vyhledávání

Corticosterone supplementation reduced selective protein kinase C isoform expression in the epidermis of adrenalectomized mice

Autor: D F, Birt, E, Duysen, W, Wang, A, Yaktine

Publikováno v: Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(6)

Previous research in this laboratory demonstrated elevated plasma corticosterone and reduced protein kinase C (PKC) activity and selective isoform expression in the epidermis of dietary energy-restricted mice. Because PKC is implicated in skin carcin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cb458ac4e863fe200f9cf80b9d433fe
https://pubmed.ncbi.nlm.nih.gov/11401919

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Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines

Autor: W, Wang, L, Heideman, C S, Chung, J C, Pelling, K J, Koehler, D F, Birt

Publikováno v: Molecular carcinogenesis. 28(2)

Apigenin, a common dietary flavonoid, has been shown to induce cell cycle arrest in both epidermal and fibroblast cells and inhibit skin tumorigenesis in murine models. The present study assessed the influence of apigenin on cell growth and the cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2336aa5cf50498ae8b3321e7b2503bd
https://pubmed.ncbi.nlm.nih.gov/10900467

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Estrogen-induced pituitary tumor development in the ACI rat not inhibited by dietary energy restriction

Autor: T J, Spady, K L, Pennington, R D, McComb, D F, Birt, J D, Shull

Publikováno v: Molecular carcinogenesis. 26(4)

We have demonstrated that a 40% restriction of dietary energy consumption virtually abolishes the development of prolactin (PRL)-producing pituitary tumors in Fischer 344 (F344) rats treated chronically with estrogen, apparently by inhibiting the abi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49abe73e5e6e345b86fee097702c5ba0
https://pubmed.ncbi.nlm.nih.gov/10569801

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Estrogen induction of prolactin-producing pituitary tumors in the Fischer 344 rat: modulation by dietary-energy but not protein consumption

Autor: J D, Shull, D F, Birt, R D, McComb, T J, Spady, K L, Pennington, C M, Shaw-Bruha

Publikováno v: Molecular carcinogenesis. 23(2)

Our laboratory is examining the hypothesis that diet may modulate the ability of estrogens to regulate cell proliferation and survival, either of which could affect development of neoplasms in estrogen-responsive tissues. In this study, we examined w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::758dc8a3a8bc1d0213da6a62452f3820
https://pubmed.ncbi.nlm.nih.gov/9808163

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Dietary energy restriction abolishes development of prolactin-producing pituitary tumors in Fischer 344 rats treated with 17beta-estradiol

Autor: T J, Spady, A M, Lemus-Wilson, K L, Pennington, D J, Blackwood, T M, Paschall, D F, Birt, R D, McComb, J D, Shull

Publikováno v: Molecular carcinogenesis. 23(2)

Reduction in energy consumption is known to inhibit development of a variety of spontaneous, carcinogen-induced, and hormone-dependent cancers, but the mechanism or mechanisms by which this occurs remain unknown. We hypothesize that energy consumptio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45c2cdb179faddd04baddac17f212ede
https://pubmed.ncbi.nlm.nih.gov/9808162

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Dietary energy restriction in the SENCAR mouse: elevation of glucocorticoid hormone levels but no change in distribution of glucocorticoid receptor in epidermal cells

Autor: A L, Yaktine, R, Vaughn, D, Blackwood, E, Duysen, D F, Birt

Publikováno v: Molecular carcinogenesis. 21(1)

The purpose of this study was to demonstrate that dietary energy restriction elevates plasma glucocorticoid hormone (GCH) levels while maintaining a circadian profile. Furthermore, we indirectly measured the effect of energy restriction on receptor a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::027c7e51352cbb1311bfc536fba1af6a
https://pubmed.ncbi.nlm.nih.gov/9473772

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Dietary fat and energy modulation of biochemical events in tumor promotion

Autor: D F, Birt, J, Copenhaver, T, Barnett, J C, Pelling, R, Luthra

Publikováno v: Advances in experimental medicine and biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b5120be5f31362366d1212a1e6fe0a2
https://pubmed.ncbi.nlm.nih.gov/9547648

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Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid

Autor: D F, Birt, D, Mitchell, B, Gold, P, Pour, H C, Pinch

Publikováno v: Anticancer research. 17(1A)

Apigenin, a widely distributed plant flavonoid, was previously found to inhibit chemically induced ornithine decarboxylase (ODC) activity and skin tumor promotion. The purpose of the present research was to determine if apigenin is effective in the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f25aefbbf2c6c7927662748d4b0c9ae
https://pubmed.ncbi.nlm.nih.gov/9066634

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