Výsledky vyhledávání

Akademický článek

Liver AMP-Activated Protein Kinase Is Unnecessary for Gluconeogenesis but Protects Energy State during Nutrient Deprivation.

Autor: Clinton M Hasenour, D Emerson Ridley, Freyja D James, Curtis C Hughey, E Patrick Donahue, Benoit Viollet, Marc Foretz, Jamey D Young, David H Wasserman

Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0170382 (2017)

AMPK is an energy sensor that protects cellular energy state by attenuating anabolic and promoting catabolic processes. AMPK signaling is purported to regulate hepatic gluconeogenesis and substrate oxidation; coordination of these processes is vital

Externí odkaz: https://doaj.org/article/80c12fbc0933474e984e7517decadd1a

Zobrazit plný text záznamu

Akademický článek

Secondary use of routinely collected administrative health data for epidemiologic research: Answering research questions using data collected for a different purpose

Autor: Scott D. Emerson, Taylor McLinden, Paul Sereda, Amanda M. Yonkman, Jason Trigg, Sandra Peterson, Robert S. Hogg, Kate A. Salters, Viviane D. Lima, Rolando Barrios

Publikováno v: International Journal of Population Data Science, Vol 9, Iss 1 (2024)

The use of routinely collected administrative health data for research can provide unique insights to inform decision-making and, ultimately, support better public health outcomes. Yet, since these data are primarily collected to administer healthcar

Externí odkaz: https://doaj.org/article/fdfdb0321c6e4f36a67fcd5b429ab61d

Zobrazit plný text záznamu

Akademický článek

Pre-mRNA splicing-associated diseases and therapies

Autor: Sierra L. Love, Joseph D. Emerson, Kazunori Koide, Aaron A. Hoskins

Publikováno v: RNA Biology, Vol 20, Iss 1, Pp 525-538 (2023)

Precursor mRNA (pre-mRNA) splicing is an essential step in human gene expression and is carried out by a large macromolecular machine called the spliceosome. Given the spliceosome's role in shaping the cellular transcriptome, it is not surprising tha

Externí odkaz: https://doaj.org/article/ffa85d3a02b74e05a7d837128a80011d

Zobrazit plný text záznamu

Akademický článek

Characterizing opioid agonist therapy uptake and factors associated with treatment retention among people with HIV in British Columbia, Canada

Autor: Kiana Yazdani, Katerina Dolguikh, Monica Ye, Jason Trigg, Ronald Joe, Scott D. Emerson, Julio S.G. Montaner, Rolando Barrios, Kate Salters

Publikováno v: Preventive Medicine Reports, Vol 35, Iss , Pp 102305- (2023)

Accidental overdoses are now the leading cause of death among people with HIV (PWH) in British Columbia (BC). We examined the utilization and retention of opioid agonist therapy (OAT).Adult PWH (≥19 years) with ≥ 1 OAT dispensation in BC between

Externí odkaz: https://doaj.org/article/000528fba2b94a49a619661335859b81

Zobrazit plný text záznamu

Akademický článek

Identification of people with low prevalence diseases in administrative healthcare records: A case study of HIV in British Columbia, Canada.

Autor: Scott D Emerson, Taylor McLinden, Paul Sereda, Viviane D Lima, Robert S Hogg, Katherine W Kooij, Amanda M Yonkman, Kate A Salters, David Moore, Junine Toy, Jason Wong, Theodora Consolacion, Julio S G Montaner, Rolando Barrios

Publikováno v: PLoS ONE, Vol 18, Iss 8, p e0290777 (2023)

IntroductionCase-finding algorithms can be applied to administrative healthcare records to identify people with diseases, including people with HIV (PWH). When supplementing an existing registry of a low prevalence disease, near-perfect specificity h

Externí odkaz: https://doaj.org/article/454a3342c2504336bd5801c201adb407

Zobrazit plný text záznamu

Plný text ve formátu HTML