Zobrazeno 1 - 10
of 81
pro vyhledávání: '"D E Woolley"'
Autor:
D E Woolley, Lynne C Tetlow
Publikováno v:
Annals of the Rheumatic Diseases. 61:737-740
To determine the effects of histamine on matrix metalloproteinase (MMP) production by human articular chondrocytes (HAC) in vitro.Conditioned culture medium from HAC cultures incubated with and without 20 microM histamine was assayed by enzymne linke
Autor:
L C Tetlow, D E Woolley
Publikováno v:
Annals of the Rheumatic Diseases. 54:549-555
OBJECTIVE--To determine the distribution, activation, and tryptase/chymase phenotype of mast cells (MCs) in the rheumatoid lesion. METHODS--MC tryptase and chymase were studied by immunohistochemistry using monoclonal antibodies and examination by br
Publikováno v:
Scandinavian Journal of Rheumatology. 22:207-214
Serum samples from 149 patients with RA and other rheumatological diseases, and 57 non-arthritic controls have been assayed for IgE antibodies to the cartilage collagen types II, IX and XI in their native and denatured state. Using an improved ELISA
Autor:
L. C. Tetlow, D. E. Woolley
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 55
Publikováno v:
Agents and Actions. 38:C182-C184
The functional importance of mast cells in modifying tumour cell behaviour has long been recognised and recent evidence suggests that mast cell: tumour interactions contribute to the growth and development of specific cancers. We have used in vitro s
Publikováno v:
Arthritis and rheumatism. 44(3)
To examine by immunohistochemistry the relative distributions of 6 matrix metalloproteinases (MMPs 1, 2, 3, 8, 9, and 13) and the 2 proinflammatory cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor alpha (TNFalpha) in osteoarthritic (O
Publikováno v:
Folia neuropathologica. 37(3)
Mast cells (MC) are heterogenous cell population. In normal human brain they are not numerous. Increases in number of mast cells within CNS occur in certain disease states including neoplasms. In capillary hemangioblastoma several authors reported ma
Autor:
M, Jeziorska, D E, Woolley
Publikováno v:
The Journal of pathology. 188(2)
An improved immunohistochemical method has been used to assess neovascularization within the vulnerable 'shoulder' regions of atherosclerotic plaques from carotid arteries. A combination of monoclonal antibodies (CD31, CD34, +/- von Willebrand factor
Publikováno v:
Biology of reproduction. 59(3)
Endometrial matrix metalloproteinases (MMPs), which increase dramatically at menstruation, are purported to cause the focal tissue breakdown at menstruation, but how their expression or activation is locally regulated is unknown. Mast cell activation
Autor:
D E Woolley, L C Tetlow
Publikováno v:
British journal of rheumatology. 37(1)
The degradation of fibrillar type II collagen is a major feature of cartilage destruction in rheumatoid arthritis (RA). Since collagenase 3 is produced by chondrocytes and preferentially degrades type II cartilage collagen, it seemed likely that this