Zobrazeno 1 - 10
of 58
pro vyhledávání: '"D E Griffin"'
Publikováno v:
The Journal of Immunology. 158:2318-2326
The unique immunologic environment of the central nervous system (CNS) regulates most local inflammatory responses. In some circumstances, however, immune-mediated injury to the brain can occur. To understand how lymphocytes are regulated within the
Publikováno v:
The Journal of Immunology. 157:4333-4340
Gangliosides may regulate the activity of the immune system in vivo, particularly within tissues such as neoplasms or the central nervous system, where they are most abundant. However, the specific mechanisms by which gangliosides modulate immune fun
Autor:
D N Irani, D E Griffin
Publikováno v:
The Journal of Immunology. 156:3850-3857
The passage of circulating lymphocytes into the central nervous system (CNS) during acute viral encephalitis was studied in vivo using fluorescently labeled cells inoculated into Sindbis virus (SV)-infected mice. Donor lymphocytes were detected in th
Publikováno v:
Journal of Clinical Microbiology. 31:118-122
The cytotoxic T-lymphocyte (CTL) response to measles virus (MV) was studied in blood samples from 13 acute- and early convalescent-phase patients with measles infection despite previous vaccination with the live-MV vaccine. MV CTL responses were also
Autor:
D E, Griffin, C H, Pan
Publikováno v:
Current topics in microbiology and immunology. 330
Isolation of measles virus in tissue culture by Enders and colleagues in the 1960s led to the development of the first measles vaccines. An inactivated vaccine provided only short-term protection and induced poor T cell responses and antibody that di
Autor:
D E, Griffin
Publikováno v:
Current topics in microbiology and immunology. 289
Alphaviruses are mosquito-borne, enveloped, plus-strand RNA viruses that cause a spectrum of diseases in humans that include fever, rash, arthritis, meningitis, and encephalomyelitis. Sindbis virus (SINV) is the prototype alphavirus, causes encephalo
Publikováno v:
Journal of Clinical Microbiology. 31:2799-2801
We analyzed Escherichia coli O157:H7 isolates from stool samples of five patients who had bloody diarrhea and were infected during a large food-borne outbreak of hemorrhagic colitis in Washington state. The isolates were assessed for Shiga-like toxin
Publikováno v:
Current topics in microbiology and immunology. 260
Publikováno v:
Annals of neurology. 46(3)
Pathological evidence suggests that alterations of the blood-brain barrier (BBB) may occur in association with human immunodeficiency virus (HIV) dementia (HIVD). Increased BBB permeability could contribute to the development of dementia by facilitat
Autor:
J F, Rowell, D E, Griffin
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(3)
SJL mice are susceptible to inflammatory autoimmune diseases of the central nervous system (CNS), while BALB/c mice are relatively resistant. To understand differences in immune responses that may contribute to autoimmune neurologic disease, we compa