Zobrazeno 1 - 10
of 26
pro vyhledávání: '"D E, Vaughan"'
Publikováno v:
The British Medical Journal, 1950 May . 1(4662), 1140-1140.
Externí odkaz:
https://www.jstor.org/stable/25357027
Autor:
D E, Vaughan, J, Loscalzo
Publikováno v:
Trends in cardiovascular medicine. 1(1)
The currently available thrombolytic agents are widely perceived to be suboptimal in terms of both efficacy and safety. This perception has in turn stimulated efforts to design and construct novel plasminogen activators endowed with improved biochemi
Autor:
N J, Brown, D E, Vaughan
Publikováno v:
Trends in cardiovascular medicine. 6(7)
In vitro and in vivo data provide evidence for an interaction between the renin-angiotensin and fibrinolytic systems. Angiotensin-converting enzyme (ACE) is strategically poised to regulate this interaction. ACE catalyzes the conversion of angiotensi
Publikováno v:
Clinical genetics. 62(1)
The detection and characterization of epistasis or non-additive gene-gene interactions remains a statistical challenge in genetic epidemiology. The recently developed combinatorial partitioning method (CPM) may overcome some of the limitations of lin
Publikováno v:
Clinical genetics. 62(1)
Thrombus formation and degradation is partly due to a complex interplay between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1). There is accumulating evidence that plasma levels of t-PA and PAI-1 may be influen
Autor:
N J, Brown, D E, Vaughan
Publikováno v:
Advances in internal medicine. 45
In vitro and in vivo data provide compelling evidence for an interaction between the RAS and thrombosis. Furthermore, angiotensin and AT1 receptor blockers may influence platelet function. ACE is strategically poised to regulate these interactions. A
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(1)
Recent data suggest an interaction between the renin-angiotensin-aldosterone system and fibrinolysis. Although previous work has focused on the effect of angiotensin II (Ang II) on plasminogen activator inhibitor (PAI-1) expression, the present study
Publikováno v:
Thrombosis and haemostasis. 81(4)
Moderate alcohol consumption has been shown to reduce the risk of ischemic heart disease potentially through its effect on specific endothelial-derived compounds. We tested the hypothesis that ethanol increases the expression of endothelial nitric ox
Autor:
D E, Vaughan
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 46(8)
Autor:
D E, Vaughan
Publikováno v:
European heart journal. 19
The plasminogen activator or fibrinolytic system is an important determinant of vascular homeostasis. It is one of the endogenous defence mechanisms against intravascular thrombus formation, which is implicated in the pathogenesis of myocardial infar