Zobrazeno 1 - 6
of 6
pro vyhledávání: '"D E, Stein"'
Publikováno v:
Digestive Diseases and Sciences. 45:890-895
Obesity and diet affect the incidence and severity of various types of cancer, including colon cancer. It is not known whether obesity, independent of diet, is a risk factor for colon adenocarcinoma. We used azoxymethane (AOM) to induce colon cancer
Autor:
S I, Goodman, D E, Stein, S, Schlesinger, E, Christensen, M, Schwartz, C R, Greenberg, O N, Elpeleg
Publikováno v:
Human mutation. 12(3)
Glutaric acidemia type I (GA1) is caused by mutations in the gene encoding the enzyme glutaryl-CoA dehydrogenase (GCD). Sixty-three pathogenic mutations identified by several laboratories are presented, 30 of them for the first time, together with da
Publikováno v:
American journal of human genetics. 59(5)
The structure of the human glutaryl coenzyme A dehydrogenase (GCD) gene was determined to contain 11 exons and to span approximately 7 kb. Fibroblast DNA from 64 unrelated glutaric acidemia type I (GA1) patients was screened for mutations by PCR ampl
Publikováno v:
Cancer research. 50(21)
gamma-L-glutamyl-L-cysteinylglycine (GSH) has been shown to inactivate 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and quench DNA crosslink precursors of BCNU. Because of the central role of 2-chloroethyl-nitrosoureas in brain tumor chemotherapy, we
Publikováno v:
Anticancer research. 10(3)
The production of DNA interstrand crosslinks (ISC) by BCNU and other bifunctional alkylators and the effects of these drugs on the repair of radiation-induced DNA-single strand breaks (SSB) were studied in two human glioblastoma used to assess both D
Autor:
M R, Fogel, C M, Knauer, L L, Andres, A S, Mahal, D E, Stein, M J, Kemeny, M M, Rinki, J E, Walker, D, Siegmund, P B, Gregory
Publikováno v:
Annals of internal medicine. 96(5)
Sixty patients with active upper gastrointestinal bleeding were randomized to received either continuous intravenous infusions of vasopressin (29 patients) or placebo (31 patients) at a rate of 40 U/h. Six hours after beginning the study, 13 patients