Zobrazeno 1 - 8
of 8
pro vyhledávání: '"D E, Selley"'
Publikováno v:
Biochemical pharmacology. 62(4)
The efficacy of heroin metabolites for the stimulation of mu opioid receptor-mediated G-protein activation was investigated using agonist-stimulated [(35)S]guanosine-5'-O-(gamma-thio)-triphosphate binding. In rat thalamic membranes, heroin and its pr
Autor:
D E, Selley, W K, Rorrer, C S, Breivogel, A M, Zimmer, A, Zimmer, B R, Martin, L J, Sim-Selley
Publikováno v:
Journal of neurochemistry. 77(4)
Heterozygous CB1 receptor knockout mice were used to examine the effect of reduced CB1 receptor density on G-protein activation in membranes prepared from four brain regions: cerebellum, hippocampus, striatum/globus pallidus (striatum/GP) and cingula
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(2)
This study examined the signal transduction correlates of mu opioid agonist efficacy in two systems: mu receptor-transfected mMOR-CHO cell and rat thalamic membranes. The potency and maximal stimulation of [35S]GTP gamma S binding by various agonists
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 83
Publikováno v:
Molecular pharmacology. 44(4)
BW373U86 is a potent and highly selective nonpeptidic agonist for delta-opioid receptors. To determine its ability to couple with G protein-linked second messenger systems, this study examined the effects of BW373U86 on the inhibition of adenylyl cyc
Publikováno v:
Molecular pharmacology. 44(4)
Low-pH pretreatment increases opioid agonist efficacy in inhibiting adenylyl cyclase in brain membranes. The mechanism of this effect was examined in membranes from cultured NG108-15 cells. Pretreatment of NG108-15 membranes at pH 4.5 before assay at
Autor:
D E, Selley, J M, Bidlack
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(1)
Human beta-endorphin 1-31 (beta-END) stimulated low-Km GTPase activity in a concentration-dependent and saturable manner in membranes prepared from the delta opioid receptor-containing hybrid cell line NG108-15 and from the mu opioid receptor-enriche
Autor:
D E, Selley, J M, Bidlack
Publikováno v:
NIDA research monograph. 95